Results 141 to 150 of about 25,138 (263)

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Nonuremic Idiopathic Calciphylaxis in a Patient With Preceding Warfarin Use and Iron Infusions

Annals of Internal Medicine: Clinical Cases
Calciphylaxis is a rare and life-threatening illness characterized by microvessel occlusion due to calcification, fibro-intimal hyperplasia, and thrombosis in the subcutaneous adipose tissue and dermis.
Miranda Huebner, Aishwarya Kothapalli, Tyler Schwiesow   +2 more
doaj   +1 more source

Mechanism of diuretics [PDF]

This infographic provides an overview of diuretics, detailing their mechanisms including thiazide, loop, potassium-sparing, carbonic anhydrase inhibitors, and osmotic diuretics, along with discussions on their side effects, site of action, prototype drug,
Wisco, Jonathan J., Cengiz, Kayra
core  

Assessing Real-World Spot Urine Sodium Values During Continuous Intravenous Infusion of Loop Diuretics

, 2021
The use of spot urine sodium (UNa)\u3e60 mmol/L as an objective measure to guide diuretic therapy in patients receiving bolus intravenous loop diuretics has been associated with increased weight loss and decreased length of stay.
Propst, Rachel, Akers, Michael
core  

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 841-858, July 2026.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique, Muhammad Muzammil Nazir, Saima Muzammil, Iqra Farzeen, Shafaq Latif, Asma Ashraf, Jorddy Neves Cruz   +6 more
wiley   +1 more source

Use of loop diuretics in patients with chronic heart failure: an observational overview. [PDF]

Open Heart, 2023
Scholte NT, Aydin D, Linssen GC, Koudstaal S, Rademaker PC, Geerlings PR, van Gent MW, Aksoy I, Oosterom L, Boersma E, Brunner-La Rocca HP, Brugts JJ.   +11 more
europepmc   +1 more source

Longer Baseline Left Ventricular Activation Time Is Associated With Lower Mortality and Lower Risk of Heart Failure Hospitalization in Cardiac Resynchronization Therapy Recipients

Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
In patients undergoing CRT implantation, a longer pre‐implant LVAT was linked to better clinical outcome (lower risk of heart failure hospitalization and all‐cause mortality), suggesting that LVAT may help refine risk stratification after CRT. ABSTRACT Introduction Many patients do not benefit from cardiac resynchronization therapy (CRT) with current ...
Sofia Marinko, Pyotr G. Platonov, Rasmus Borgquist   +2 more
wiley   +1 more source

Association of SGLT2 Inhibitor With Stroke in Type 2 Diabetes With Diabetic Retinopathy: A Multicenter Electronic Health Record Data Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5614-5626, July 2026.
ABSTRACT Aims Diabetic retinopathy (DR) is linked to elevated risks of cerebrovascular diseases. Whether sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) reduce stroke risk in patients with type 2 diabetes (T2D) and DR remains uncertain. Materials and Methods We conducted a retrospective cohort study using the TriNetX Research Network.
Kuo‐En Chen, Po‐Chun Wang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

Dapagliflozin vs. metolazone in heart failure resistant to loop diuretics. [PDF]

Eur Heart J, 2023
Yeoh SE, Osmanska J, Petrie MC, Brooksbank KJM, Clark AL, Docherty KF, Foley PWX, Guha K, Halliday CA, Jhund PS, Kalra PR, McKinley G, Lang NN, Lee MMY, McConnachie A, McDermott JJ, Platz E, Sartipy P, Seed A, Stanley B, Weir RAP, Welsh P, McMurray JJV, Campbell RT.   +23 more
europepmc   +1 more source