Results 61 to 70 of about 25,138 (263)

Cardiac dysfunction, congestion and loop diuretics: their relationship to prognosis in heart failure [PDF]

, 2016
Background: Diuretics are the mainstay of treatment for congestion but concerns exist that they adversely affect prognosis. We explored whether the relationship between loop diuretic use and outcome is explained by the underlying severity of ...
Cleland, JG, Shah, P, Kazmi, Syed, Kazmi, S, Zhang, Jufen, Clark, Andrew L., Pellicori, Pierpaolo, Urbinati, Alessia, Shah, Parin, Cleland, John G.F., Kallvikbacka-Bennett, A, Clark, AL, Pellicori, P, Urbinati, A, Kallvikbacka-Bennett, Anna, Zhang, J   +15 more
core   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Diuretics — a review of the current knowledge

, 2023
Diuretics are drugs that increase diuresis and natriuresis. Diuretics reduce sodium reabsorption in the proximal tubule (SGLT2 inhibitors, carbonic anhydrase inhibitors), the loop of Henle (loop diuretics), the distal tubule (thiazide and thiazide-like ...
Więcek, Andrzej; Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia in Katowice, Surma, Stanisław; Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia in Katowice, Adamczak, Marcin; Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia in Katowice   +2 more
core   +1 more source

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

British Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Laura M. Dember, Todd A. Miano, Tat‐Thang Vo, Allison W. Willis, Charles E. Leonard   +8 more
wiley   +1 more source

External validation of the BAN‐ADHF diuretic‐resistance score in the DAPA‐RESIST clinical trial

British Journal of Clinical Pharmacology, EarlyView.
Diuretic resistance in worsening heart failure (HF) is associated with poorer outcomes and, although common, can be challenging to identify. The recently developed BAN‐ADHF score can potentially identify patients with worsening HF at risk of diuretic resistance.
Dominic M. Alfonso, Kieran F. Docherty, Matthew M. Y. Lee, Patrick B. Mark, Alex McConnachie, Joanna Osmanska, Bethany Stanley, Atefeh Talebi, Mark C. Petrie, John J. V. McMurray, Ross T. Campbell   +10 more
wiley   +1 more source

Reward Processing in Binge Eating and Harmful Drinking: A Systematic Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating and harmful drinking commonly co‐occur, which worsens the physical and psychological consequences associated with either behavior alone. Reward processing alterations have been demonstrated among individuals who engage in binge eating or harmful drinking alone; however, there is limited understanding of how different ...
Taylor N. Breddy, Kendall M. Schmidt, Lindsay P. Bodell   +2 more
wiley   +1 more source

Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide

Nature Communications, 2022
Loop diuretics including bumetanide inhibit Na+-K+-Cl−-cotransporters (NKCCs) and are used for the treatment of edema and hypertension. Here, Zhao et. al.
Yongxiang Zhao, Kasturi Roy, Pietro Vidossich, Laura Cancedda, Marco De Vivo, Biff Forbush, Erhu Cao   +6 more
doaj   +1 more source

Use of diuretics and risk of incident gout : Population-based case-control study

, 2014
Objective: Use of diuretics has been associated with an increased risk of gout. Data for different types of diuretics are scarce. This study investigated the association between use of loop diuretics, thiazide or thiazide-like diuretics, and potassium ...
Meier, Christoph R., Jick, Susan S, Christoph R. Meier, Bodmer, Michael, Meier, Christoph R, Saskia Bruderer, Michael Bodmer, Susan S. Jick, Jick, Susan S., Bruderer, Saskia   +9 more
core   +1 more source

Magnitude, Patterns and Factors Associated With Sensorineural Hearing Loss Among Hypertensive Adults at a Tertiary Hospital in Northern Tanzania

Eye &ENT Research, EarlyView.
ABSTRACT Background Hearing loss affects 1.5 billion people globally, with sensorineural hearing loss (SNHL) linked to hypertension. Hypertension affects 1.39 billion people worldwide and its prevalence is rising sharply in Sub‐Saharan Africa. While 12% of Tanzanian population has cardiovascular diseases, including hypertension and recent studies ...
Johnson Shayo, Denis Katundu, Abdallah Jonas, Peter Shija   +3 more
wiley   +1 more source

Role of Diuretics and Ultrafiltration in Congestive Heart Failure

Pharmaceuticals, 2013
Volume overload in heart failure (HF) results from neurohumoral activation causing renal sodium and water retention secondary to arterial underfilling. Volume overload not only causes signs and symptoms of congestion, but can impact myocardial remodeling
Jo Ann Lindenfeld, Robert Schrier, Fawaz Al Ammary, Dmitry Shchekochikhin   +3 more
doaj   +1 more source