Results 11 to 20 of about 17,797 (277)

Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis.

open access: goldPLoS Medicine, 2007
BackgroundLoperamide is widely used in adults for acute diarrhea. However, its use in children has been discouraged by the World Health Organization and the American Academy of Pediatrics owing to concerns over safety and efficacy in young children ...
Su-Ting T Li   +2 more
doaj   +3 more sources

Loperamide: From antidiarrheal to analgesic

open access: bronzeJournal of Opioid Management, 2013
Loperamide, an antidiarrheal drug has been observed to produce analgesia in animal models of pain. However, the exact mechanism underlying loperamide analgesia needs further studies.
Rakesh Kumar
openaire   +5 more sources

Loperamide Inhibits Replication of Severe Fever with Thrombocytopenia Syndrome Virus

open access: yesViruses, 2021
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by the SFTS virus (SFTSV). SFTS is mainly prevalent in East Asia.
Shuzo Urata   +2 more
doaj   +1 more source

The Potential Mechanisms behind Loperamide-Induced Cardiac Arrhythmias Associated with Human Abuse and Extreme Overdose

open access: yesBiomolecules, 2023
Loperamide has been a safe and effective treatment for diarrhea for many years. However, many cases of cardiotoxicity with intentional abuse of loperamide ingestion have recently been reported.
Hua Rong Lu   +7 more
doaj   +1 more source

Autonomic effects of electroacupuncture in opioid-induced constipation in male rats. [PDF]

open access: yesPhysiol Rep
Abstract The efficacy of electroacupuncture (EA) for opioid‐induced constipation (OIC) has been reported; however, the mechanism has not been sufficiently studied, and the details have not been clarified. The aims of this study were to demonstrate the delay in rat colonic transit (CT) caused by loperamide, a peripheral μ‐opioid receptor agonist, and to
Okada M, Itoh K, Kitakoji H, Imai K.
europepmc   +2 more sources

Radiographic evaluation of the effect of diphenoxylate and loperamide on the transit time of the contrast media of gastro-intestinal tract in cat [PDF]

open access: yesĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2021
Radiography with contrast media is a diagnostic imaging technique with high-resolution that plays a prominent role in showing the transit time of gastrointestinal system.
Abdolvahed Moarabi   +3 more
doaj   +1 more source

A Heart-Wrenching Case of Loperamide Toxicity [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2019
Background: Loperamide is an insoluble meperidine analog that is commonly used for diarrhea. It is an inexpensive and frequently available over the counter drug.
Sadaf Sheikh, Muhammad Akbar Baig
doaj   +1 more source

Loperamide Overdose [PDF]

open access: yesCureus, 2019
In light of the opioid epidemic, cardiac complications following a loperamide overdose are a growing concern for patients presenting to the emergency department (ED). Here, we present the case of a 35-year-old male with long QT syndrome who presented following a loperamide overdose and was receiving multiple shocks because of the resulting arrhythmias ...
Arnold, Casey   +1 more
openaire   +2 more sources

Redetermination of loperamide monohydrate [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
The structure of the title compound {systematic name: 4-[4-(4-chloro-phen-yl)-4-hy-droxy-piperidin-1-yl]-N,N-dimethyl-2,2-di-phenyl-butanamide monohydrate}, C(29)H(33)ClN(2)O(2)·H(2)O, has been redetermined at 170 (2) K. The redetermination is of significantly higher precision than the previous structure determination at room temperature and includes ...
Jasinski, Jerry P.   +4 more
openaire   +5 more sources

Quantitative analysis of Loperamide hydrochloride in the presence its acid degradation products [PDF]

open access: yesHemijska Industrija, 2009
The aim of this work was to develop a new RP-HPLC method for the determination of loperamide hydrochloride in the presence of its acid degradation products.
Savić Ivana M.   +3 more
doaj   +1 more source

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