Results 31 to 40 of about 22,601 (285)
European Heart Journal: Case Reports, 2023 Background Loperamide at supratherapeutic doses can cause cardiac toxicity, presenting as cardiogenic shock, prolonged QT, malignant arrhythmias, or in severe cases sudden cardiac death. Surreptitious loperamide use is difficult to diagnose.
V. Hegde +4 more
semanticscholar +1 more source
Local loperamide injection reduces mechanosensitivity of rat cutaneous, nociceptive C-fibers. [PDF]
PLoS ONE, 2012 Loperamide reverses signs of mechanical hypersensitivity in an animal model of neuropathic pain suggesting that peripheral opioid receptors may be suitable targets for the treatment of neuropathic pain.
Matthias Ringkamp +8 more
doaj +1 more source
Nutrients, 2022 Although Ligilactobacillus salivarius Li01 (Li01) has shown much promise in preventing multiple gastrointestinal diseases, the potential of the probiotic in alleviating constipation and the related mechanisms remain unclear. In this study, the effects of
Bo-Chen Qiu +8 more
semanticscholar +1 more source
Frontiers in Microbiology, 2022 Slow transit constipation (STC) is the most common type of functional constipation. Drugs with good effects and few side effects are urgently needed form the treatment of STC.
Xiaoyu Gao +9 more
semanticscholar +1 more source
Frontiers in Nutrition, 2022 Probiotics have received widespread attention as a healthy ingredient. The preventive effect of Bifidobacterium lactis TY-S01 on loperamide-induced constipation in mice was investigated in this study.
Tian Tang +8 more
semanticscholar +1 more source
Is there such a thing as a 'lope' dope? Analysis of loperamide-related European Medicines Agency (EMA) pharmacovigilance database reports. [PDF]
PLoS ONE, 2018 BACKGROUND:Among over-the-counter (OTC) drugs, loperamide has recently emerged for its potential of misuse and cardiotoxicity issues. Hence, we aimed here at assessing the loperamide-related cases being reported to the EMA's EudraVigilance (EV) database.
Fabrizio Schifano, Stefania Chiappini
doaj +1 more source
Case Reports in Oncology, 2021 Irinotecan hydrochloride (irinotecan) is a chemotherapeutic agent used in the treatment of solid tumors. In addition to severe neutropenia and delayed diarrhea, irinotecan causes cholinergic syndrome, characterized by abdominal pain and acute diarrhea ...
Kazuki Uchiyama +4 more
doaj +1 more source
Effects of loperamide on the human hypothalamo-pituitary-adrenal axis in vivo and in vitro. [PDF]
, 1992 Loperamide, an opiate agonist of high specificity for p-receptors, was recently reported to suppress ACTH and cortisol levels in normal subjects, but not in patients with proven ACTH-dependent Cushing’s disease. However, there is little information on
Auernhammer, Christoph J. +4 more
core +1 more source
Frontiers in Nutrition, 2022 In this study, the laxative effect of Bacillus coagulans BC01 (BC01) in mice was investigated using a functional constipation mouse model. Six-week-old male specific pathogen-free (SPF) Kunming mice were randomly divided into five groups: normal control ...
Xu Zhou +6 more
semanticscholar +1 more source
Effects of Loperamide on Mechanical Allodynia Induced by Herpes Simplex Virus Type-1 in Mice
Journal of Pharmacological Sciences, 2007 In the present study, we investigated whether the peripherally acting µ-opioid receptor agonist loperamide would inhibit allodynia in the non-inflamed dermatome of mice with herpetic pain.
Atsushi Sasaki +5 more
doaj +1 more source