Results 51 to 60 of about 23,058 (301)

The potential of Quercetin to protect against loperamide‐induced constipation in rats

open access: yesFood Science & Nutrition, 2021
Constipation is the most common gastrointestinal complaint all over the world, and it is a risk factor of colorectal cancer. In this study, the protective of Quercetin against loperamide‐induced constipation and its potential mechanism in a rat model ...
Wenhui Liu, A. Zhi
semanticscholar   +1 more source

Causes and assessment of faecal incontinence [PDF]

open access: yes, 1999
Faecal incontinence remains a taboo subject and patients frequently conceal their symptoms, because of fear and embarrassment. Sensitive and appropriate assessment will encourage people to seek advice and treatment if required. This article discusses the
Chelvanayagam, Sonya
core   +1 more source

Antioxidant activity and laxative effects of tannin-enriched extract of Ecklonia cava in loperamide-induced constipation of SD rats

open access: yesPLoS ONE, 2021
To investigate the role of tannin-enriched extracts of Ecklonia cava (TEE) on the regulation of oxidative balance and laxative activity in chronic constipation, we investigated alterations after exposure to TEE, on constipation phenotypes, muscarinic ...
J. Kim   +9 more
semanticscholar   +1 more source

Fecal incontinence: the quality of reported randomized, controlled trials in the last ten years. [PDF]

open access: yes, 2008
This study was designed to analyze the characteristics and the quality of reporting of randomized, controlled trials published during the last ten years on fecal ...
Chelvanayagam, Sonya   +2 more
core   +1 more source

Loperamide Induced Life Threatening Ventricular Arrhythmia

open access: yesCase Reports in Cardiology, 2016
Loperamide is over-the-counter antidiarrheal agent acting on peripherally located μ opioid receptors. It is gaining popularity among drug abusers as opioid substitute. We report a case of a 46-year-old male that was presented after cardiac arrest.
Ankit Upadhyay   +6 more
doaj   +1 more source

Loperamide Inhibits Tachykinin NK3-Receptor-Triggered Serotonin Release Without Affecting NK2-Receptor-Triggered Serotonin Release From Guinea Pig Colonic Mucosa

open access: yesJournal of Pharmacological Sciences, 2005
The effect of loperamide on tachykinin NK2- and NK3-receptor-mediated 5-HT outflow from guinea pig colonic mucosa was investigated in vitro. The selective tachykinin NK2-receptor agonist [β-Ala8]-neurokinin A4–10 (βAla-NKA) or the selective NK3-receptor ...
Shu-ichi Kojima   +2 more
doaj   +1 more source

Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

open access: yesbioRxiv, 2020
Increasing evidence suggests that induction of lethal autophagy carries potential significance for the treatment of glioblastoma (GBM). In continuation of previous work, we demonstrate that pimozide and loperamide trigger an ATG5- and ATG7-dependent type
Nina Meyer   +10 more
semanticscholar   +1 more source

Antidiarrheal action of Zataria multiflora hydroalcoholic and hexane extracts in mice [PDF]

open access: yes, 2017
Introduction: Zataria multiflora Boiss. is an indigenous herbal plant found in many parts of Iran. This herb is traditionally used as a remedy for treating gastrointestinal disorders including diarrhea.
Asghari, Gholamreza.   +2 more
core   +2 more sources

Xiao Cheng Qi Decoction, an Ancient Chinese Herbal Mixture, Relieves Loperamide-Induced Slow-Transit Constipation in Mice: An Action Mediated by Gut Microbiota

open access: yesPharmaceuticals
Xiao Cheng Qi (XCQ) decoction, an ancient Chinese herbal mixture, has been used in treating slow-transit constipation (STC) for years. The underlying action mechanism in relieving the clinical symptoms is unclear.
Amanguli Tuohongerbieke   +8 more
semanticscholar   +1 more source

Lacticaseibacillus paracasei NCU-04 relieves constipation and the depressive-like behaviors induced by loperamide in mice through the microbiome-gut-brain axis

open access: yesCurrent Research in Food Science
Constipation is a prevalent gastrointestinal condition that significantly affects patients' physical and mental well-being, yet current treatments often lack safety and efficacy.
Shengjie Li   +7 more
semanticscholar   +1 more source

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