Results 101 to 110 of about 46,511 (209)

Atazanavir-Based Therapy Is Associated with Higher Hepatitis C Viral Load in HIV Type 1-Infected Subjects with Untreated Hepatitis C [PDF]

, 2013
Comunicación cortaWe assessed the relationship between atazanavir (ATV)-based antiretroviral treatment (ART) and plasma hepatitis C virus (HCV) viral load in a population of HIV/HCV-coinfected patients.
Girón-González, José-Antonio, López Cortés, Luis Fernando, Mira, Jose A., Márquez, Manuel, Rivero-Juarez, Antonio, Santos-Gil, Ignacio De Los   +5 more
core  

Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24

Journal of Lipid Research, 2012
Protein farnesyltransferase (FTase) inhibitors, generally called “FTIs,” block the farnesylation of prelamin A, inhibiting the biogenesis of mature lamin A and leading to an accumulation of prelamin A within cells.
Sandy Y. Chang, Sarah E. Hudon-Miller, Shao H. Yang, Hea-Jin Jung, John M. Lee, Emily Farber, Thangaiah Subramanian, Douglas A. Andres, H.Peter Spielmann, Christine A. Hrycyna, Stephen G. Young, Loren G. Fong   +11 more
doaj   +1 more source

The role of drug resistance in poor viral suppression in rural South Africa: findings from a population-based study. [PDF]

, 2020
BACKGROUND:Understanding factors driving virological failure, including the contribution of HIV drug resistance mutations (DRM), is critical to ensuring HIV treatment remains effective.
Barnhart, Scott, Gilmore, Hailey J, Grignon, Jessica S, Hunt, Gillian, Liegler, Teri, Lippman, Sheri A, Mooney, Alyssa C, Prach, Lisa M, Puren, Adrian, Truong, Hong-Ha M   +9 more
core  

Comparable Efficacy of Lopinavir/Ritonavir and Remdesivir in Reducing Viral Load and Shedding Duration in Patients with COVID-19

Microorganisms
The spread of COVID-19 has significantly increased research on antiviral drugs and measures such as case isolation and contact tracing. This study compared the effects of lopinavir/ritonavir and remdesivir on COVID-19 patients with a control group ...
Choon-Mee Kim, Jae Keun Chung, Sadia Tamanna, Mi-Seon Bang, Misbah Tariq, You Mi Lee, Jun-Won Seo, Da Young Kim, Na Ra Yun, Jinjong Seo, Yuri Kim, Min Ji Kim, Dong-Min Kim, Nam-Hyuk Cho   +13 more
doaj   +1 more source

Lopinavir [PDF]

Reactions Weekly, 2020
openaire   +2 more sources

Experience with Empirical Treatment of Severe Acute Respiratory Syndrome Due to Coronavirus, Genotype IV

Антибиотики и Химиотерапия, 2020
Foreign experience with empirical management of severe acute respiratory syndrome (SARS) due to coronavirus, genotype IV is described. It is indicated that the data on the efficacy of ribavirin with respect to SARS in the patients are contradictory.
V. N. Shchukina, S. Ya. Loginova, S. V. Borisevich, V. P. Bondarev   +3 more
doaj  

CircRNA regulates the liquid-liquid phase separation of ATG4B, a novel strategy to inhibit cancer metastasis?

Cell Stress
Anoikis is a common programmed death for most of detached cells, but cancer cells can obtain anoikis resistance to facilitate their distant metastasis through the circulation system.
Ziyuan Guo, Yang Chen, Yaran Wu, Jiqin Lian   +3 more
doaj   +1 more source

“Conditional scholarships” for HIV/AIDS health workers: educating and retaining the workforce to provide antiretroviral treatment in sub- Saharan Africa [PDF]

In spite of recent large-scale efforts to roll out ART in developing countries, millions of people who need ART currently do not receive it. Without large increases in the number of health workers to treat HIV/AIDS (HAHW) in the next few years, most ...
David E. Bloom, Till Bärnighausen
core  

Remdesivir as a possible therapeutic option for the COVID-19 [PDF]

, 2020
Al-Homoud, Ali H., Al-Tawfiq, Jaffar A., Memish, Ziad A.   +2 more
core   +1 more source

(The Lancet)red: a missed opportunity. [PDF]

, 2006
Alexandra Calmy, Donnelly, Felipe Garcia de la Vega, Fernando Pascual, Gilks, Marseille, Nathan Ford, Sheila Shettle, Williams   +8 more
core   +2 more sources