Results 101 to 110 of about 31,541 (206)

Pharmacokinetics of lopinavir determined with an ELISA test in youths with perinatally acquired HIV [PDF]

, 2013
Objective: To investigate the plasma levels of lopinavir by enzyme-linked immunosorbent assay (ELISA) in a cohort of patients who were vertically infected with human immunodeficiency virus 1 (HIV).
Sormani, Maria Pia, Viscoli, Claudio, Francesca Ginocchio, Nulvesu, L, Prinapori, Roberta, Lucia Taramasso, Schiavetti, Irene, Franca Miletich, Di Biagio, Antonio, Maria Pia Sormani, Claudio Viscoli, Loredana Nulvesu, Di Biagio, A, Raffaella Rosso, Ginocchio, Francesca, Miletich, F, Rosso, Raffaella, Roberta Prinapori, Vania Giacomet, Nulvesu, Loredana, Alessio Signori, Giacomet, Vania, Antonio Di Biagio, De Hoffer, Laura, Giacomet, V, Laura De Hoffer, Miletich, Franca, Elisa Furfaro, Taramasso, Lucia, Ginocchio, F, Irene Schiavetti, Signori, Alessio, Furfaro, Elisa   +32 more
core   +1 more source

Lopinavir [PDF]

Reactions Weekly, 2020
openaire   +2 more sources

The effect of lopinavir - ritonavir on mortality in COVID-19 pneumonia

Northwestern Medical Journal
Aim: COVID-19 is a lethal disease for which there is still no specific treatment. The study aims to retrospectively investigate the effect of adding lopinavir/ritonavir to the treatment of patients using favipiravir (in the ward or intensive care unit ...
Muhammed Emin Demirkol, Emine Afşin, Mehmet Balcı   +2 more
doaj   +1 more source

Comparable Efficacy of Lopinavir/Ritonavir and Remdesivir in Reducing Viral Load and Shedding Duration in Patients with COVID-19

Microorganisms
The spread of COVID-19 has significantly increased research on antiviral drugs and measures such as case isolation and contact tracing. This study compared the effects of lopinavir/ritonavir and remdesivir on COVID-19 patients with a control group ...
Choon-Mee Kim, Jae Keun Chung, Sadia Tamanna, Mi-Seon Bang, Misbah Tariq, You Mi Lee, Jun-Won Seo, Da Young Kim, Na Ra Yun, Jinjong Seo, Yuri Kim, Min Ji Kim, Dong-Min Kim, Nam-Hyuk Cho   +13 more
doaj   +1 more source

Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24

Journal of Lipid Research, 2012
Protein farnesyltransferase (FTase) inhibitors, generally called “FTIs,” block the farnesylation of prelamin A, inhibiting the biogenesis of mature lamin A and leading to an accumulation of prelamin A within cells.
Sandy Y. Chang, Sarah E. Hudon-Miller, Shao H. Yang, Hea-Jin Jung, John M. Lee, Emily Farber, Thangaiah Subramanian, Douglas A. Andres, H.Peter Spielmann, Christine A. Hrycyna, Stephen G. Young, Loren G. Fong   +11 more
doaj   +1 more source

Synthesis and Characterization of Impurities in the Production Process of Lopinavir [PDF]

, 2014
Lopinavir is an antiretroviral drug used for the inhibition of HIV protease. Four related substances of lopinavir were observed during the manufacturing process of lopinavir in the laboratory and they were identified.
Srinivas GARAGA, Chandiran TAKSHINAMOORTHY, Ambati RAGHAVA REDDY, Andra NAIDU   +3 more
core   +1 more source

Experience with Empirical Treatment of Severe Acute Respiratory Syndrome Due to Coronavirus, Genotype IV

Антибиотики и Химиотерапия, 2020
Foreign experience with empirical management of severe acute respiratory syndrome (SARS) due to coronavirus, genotype IV is described. It is indicated that the data on the efficacy of ribavirin with respect to SARS in the patients are contradictory.
V. N. Shchukina, S. Ya. Loginova, S. V. Borisevich, V. P. Bondarev   +3 more
doaj  

Pharmacokinetics of adjusted-dose 8-hourly lopinavir/ritonavir in HIV-infected children co-treated with rifampicin [PDF]

, 2019
: Objectives: To evaluate the proportion of children with lopinavir C-min >= 1 mg/L when receiving a novel 8-hourly lopinavir/ritonavir dosing strategy during rifampicin co-treatment.
Van Rie, Annelies, Rabie, Helena, McIlleron, Helen, Rawizza, Holly, Zar, Heather, Wiesner, Lubbe, Zuidewind, Peter, Winckler, Jana   +7 more
core  

CircRNA regulates the liquid-liquid phase separation of ATG4B, a novel strategy to inhibit cancer metastasis?

Cell Stress
Anoikis is a common programmed death for most of detached cells, but cancer cells can obtain anoikis resistance to facilitate their distant metastasis through the circulation system.
Ziyuan Guo, Yang Chen, Yaran Wu, Jiqin Lian   +3 more
doaj   +1 more source

Repurposing anti-retroviral drugs to treat NF2-related tumours: a protocol for a phase 0 trial (RETREAT). [PDF]

BMJ Open
Campbell S, Beaney K, Hosking J, Sorrell L, Allgar V, Aspinall PJ, Ammoun S, Evans DG, Hanemann CO, Kingdon S.   +9 more
europepmc   +1 more source