Results 91 to 100 of about 46,511 (209)
ChemistrySelect, Volume 11, Issue 9, 5 March 2026.ABSTRACT Monkeypox is a reemerging zoonotic disease that has been spreading worldwide. Different approaches are being conducted to find effective treatments for this disease. To accelerate therapeutic discovery, we propose telomere‐binding protein (TBP) as a potential drug target because of its important role during virus maturation.
Edinson Gervacio‐Villarreal +12 more
wiley +1 more source
Intervenciones farmacológicas para el tratamiento de la Enfermedad por Coronavirus (COVID-19)
Anales de la Facultad de Medicina, 2020 Varios fármacos han sido propuestos como alternativas terapéuticas para COVID-19. Se efectuó una búsqueda sistematica en MEDLINE (vía PubMed) hasta el 20 de marzo de 2020, con el fin de identificar la evidencia disponible sobre intervenciones ...
Fabiola Huaroto +7 more
doaj +1 more source
NanomaterialsLopinavir (LPV) and ritonavir (RTV) are two of the essential antiretroviral active pharmaceutical ingredients (APIs) characterized by poor solubility. Hence, attempts have been made to improve both their solubility and dissolution rate.
Ewelina Łyszczarz +5 more
doaj +1 more source
The glucose transporter PfHT1 is an antimalarial target of the HIV protease inhibitor lopinavir [PDF]
, 2015 Malaria and HIV infection are coendemic in a large portion of the world and remain a major cause of morbidity and mortality. Growing resistance of Plasmodium species to existing therapies has increased the need for new therapeutic approaches.
Armstrong, Christopher +4 more
core +2 more sources
Brief Summary of Potential SARS-CoV-2 Prophylactic and Treatment Drugs in the Emergency Department [PDF]
, 2020 As of March 30th, 2020 there were 161,807 total cases and 2,953 total deaths of SARS-CoV-2 in the United States, with the number of cases expected to rise.
Brown, Cortlyn +2 more
core
Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: A multicentre retrospective matched cohort study [PDF]
, 2003 Objectives. To investigate the possible benefits and adverse effects of the addition of lopinavir/ritonavir to a standard treatment protocol for the treatment of severe acute respiratory syndrome. Design. Retrospective matched cohort study. Setting. Four
Chan, KS +11 more
core
Switching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring. [PDF]
, 2009 In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring is not generally available in resource-limited settings. We examined switching from
Boulle, A +18 more
core +4 more sources
Update on therapeutic options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [PDF]
, 2016 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core +1 more source
Pharmaceutics, 2019 Nanostructured lipid carriers (NLCs) loaded with lopinavir (LPV) were prepared by the high-shear homogenization method. The LPV-NLCs formulations were freeze-dried using trehalose as a cryoprotectant.
Arshad Ali Khan +4 more
doaj +1 more source
The effect of lopinavir - ritonavir on mortality in COVID-19 pneumonia
Northwestern Medical JournalAim: COVID-19 is a lethal disease for which there is still no specific treatment. The study aims to retrospectively investigate the effect of adding lopinavir/ritonavir to the treatment of patients using favipiravir (in the ward or intensive care unit ...
Muhammed Emin Demirkol +2 more
doaj +1 more source