Results 91 to 100 of about 32,499 (205)

Clinical experience with the combined use of lopinavir/ritonavir and rifampicin. [PDF]

, 2009
Contains fulltext : 79592.pdf (Publisher’s version ) (Open Access)Thirty-four patients treated concomitantly with lopinavir/ritonavir and rifampicin were evaluated.
van Crevel, Reinout, Burger, David M., Boeree, M.J., Gras, Luuk, Nijland, H.M.J., Brinkman, K., Prins, J.M., Crevel, R. van, Aarnoutse, Rob E., Juttmann, J.R., L'homme, R.F.A., Juttmann, Job R., Burger, D.M., Nijland, Hanneke M. J., Boeree, Martin, Prins, Jan M., Aarnoutse, R.E., Brinkman, Kees, Gras, L., L'homme, Rafaëlla Fa   +19 more
core   +1 more source

Lipid disorders in antiretroviral-naive patients treated with lopinavir/ritonavir-based HAART: frequency, characterization and risk factors

, 2005
Objectives: The aim of this study was to evaluate the frequency, characteristics and risk factors of lipid changes associated with lopinavir/ritonavir treatment in antiretroviral-naive patients.
Arribas, José R., Rubio García, Rafael, Montes, María Luisa   +2 more
core   +1 more source

Tinjauan Keamanan Penggunaan Lopinavir dan Ritonavir Untuk Terapi Covid-19 Pada Anak

, 2021
Kombinasi Lopinavir dan Ritonavir merupakan salah satu obat yang golongan antiviral yang digunakan sebagai terapi potensial untuk pengobatan pada pasien COVID-19. Efektivitas penggunaan Lopinavir dan Ritonavir pada pasien COVID-19 masih dalam uji klinis.
Suyasa, Agus Baratha, Lewar, Emanuel Ileatan   +1 more
core   +1 more source

Freeze-Dried Lopinavir-Loaded Nanostructured Lipid Carriers for Enhanced Cellular Uptake and Bioavailability: Statistical Optimization, in Vitro and in Vivo Evaluations

Pharmaceutics, 2019
Nanostructured lipid carriers (NLCs) loaded with lopinavir (LPV) were prepared by the high-shear homogenization method. The LPV-NLCs formulations were freeze-dried using trehalose as a cryoprotectant.
Arshad Ali Khan, Jahanzeb Mudassir, Safia Akhtar, Vikneswaran Murugaiyah, Yusrida Darwis   +4 more
doaj   +1 more source

Lopinavir/ritonavir reduces lamotrigine plasma concentrations in healthy subjects. [PDF]

, 2006
Contains fulltext : 50676.pdf (Publisher’s version ) (Open Access)BACKGROUND: Limited data are available about the effect of lopinavir and low-dose ritonavir on glucuronidation. Lamotrigine undergoes glucuronidation.
Burger, D.M., Hofstede, H.J.M. ter, Caliskan-Yassen, N., Lee, M.J. van der, Graaff, M.J.A. de, Ewijk-Beneken Kolmer, E.W.J. van, Koopmans †, P.P., Dawood, L.   +7 more
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In Vitro Antiviral Interaction of Lopinavir with Other Protease Inhibitors

, 2002
The in vitro inhibition of wild-type human immunodeficiency virus (HIV) by combinations of lopinavir and six other protease inhibitors over a range of two-drug combination ratios was evaluated.
Dale J. Kempf, Hongmei Mo, Lixin Han, Akhteruzzaman Molla, Ann Hsu, C. Thomas Lin, Sudthida Vasavanonda   +6 more
core   +1 more source

Lopinavir/ritonavir for the treatment of SARS, MERS and COVID-19: a systematic review

, 2020
OBJECTIVE: Lopinavir/ritonavir has been used for the treatment of Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) coronavirus infections.
Servillo G., Vargas M., Einav S.
core   +1 more source

Pharmacokinetics of lopinavir determined with an ELISA test in youths with perinatally acquired HIV [PDF]

, 2013
Objective: To investigate the plasma levels of lopinavir by enzyme-linked immunosorbent assay (ELISA) in a cohort of patients who were vertically infected with human immunodeficiency virus 1 (HIV).
Sormani, Maria Pia, Viscoli, Claudio, Francesca Ginocchio, Nulvesu, L, Prinapori, Roberta, Lucia Taramasso, Schiavetti, Irene, Franca Miletich, Di Biagio, Antonio, Maria Pia Sormani, Claudio Viscoli, Loredana Nulvesu, Di Biagio, A, Raffaella Rosso, Ginocchio, Francesca, Miletich, F, Rosso, Raffaella, Roberta Prinapori, Vania Giacomet, Nulvesu, Loredana, Alessio Signori, Giacomet, Vania, Antonio Di Biagio, De Hoffer, Laura, Giacomet, V, Laura De Hoffer, Miletich, Franca, Elisa Furfaro, Taramasso, Lucia, Ginocchio, F, Irene Schiavetti, Signori, Alessio, Furfaro, Elisa   +32 more
core   +1 more source

The effect of lopinavir - ritonavir on mortality in COVID-19 pneumonia

Northwestern Medical Journal
Aim: COVID-19 is a lethal disease for which there is still no specific treatment. The study aims to retrospectively investigate the effect of adding lopinavir/ritonavir to the treatment of patients using favipiravir (in the ward or intensive care unit ...
Muhammed Emin Demirkol, Emine Afşin, Mehmet Balcı   +2 more
doaj   +1 more source

Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24

Journal of Lipid Research, 2012
Protein farnesyltransferase (FTase) inhibitors, generally called “FTIs,” block the farnesylation of prelamin A, inhibiting the biogenesis of mature lamin A and leading to an accumulation of prelamin A within cells.
Sandy Y. Chang, Sarah E. Hudon-Miller, Shao H. Yang, Hea-Jin Jung, John M. Lee, Emily Farber, Thangaiah Subramanian, Douglas A. Andres, H.Peter Spielmann, Christine A. Hrycyna, Stephen G. Young, Loren G. Fong   +11 more
doaj   +1 more source