Results 11 to 20 of about 28,228 (226)
ChemInform, 2004 The title compound (systematic name: [2-butyl-4-chloro-1-[2'-(2-trityl-2H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-imidazol-5-yl]methanol), C(41)H(37)ClN(6)O, crystallizes in the centrosymmetric space group P-1 with two independent molecules in the asymmetric unit.
Sieron, L. +6 more
openaire +2 more sources
Losartan Inhibits SARS-CoV-2 Replication in Vitro
Journal of Pharmacy & Pharmaceutical Sciences, 2021 Purpose: SARS-CoV-2 infection is associated with substantial mortality and high morbidity. This study tested the effect of angiotensin II type I receptor blocker, losartan, on SARS-CoV-2 replication and inhibition of the papain-like protease of the virus.
Reza Nejat +6 more
doaj +1 more source
Artery Research, 2020 Purpose/Background/Objectives: Hypertension (HAS) represents 9.4 million deaths from all the cases of cardiovascular disease worldwide [1]. The pulse wave velocity (PWV) and some hemodynamic parameters have been associated with this outcome [2,3 ...
Mayra Jimenez +7 more
doaj +1 more source
Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan. [PDF]
PLoS ONE, 2015 Exposure of platelets to collagen triggers the formation of a platelet clot. Pharmacological agents capable of inhibiting platelet activation by collagen are thus of potential therapeutic interest.
Peng Jiang +5 more
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Fenofibrate and losartan [PDF]
Annals of the Rheumatic Diseases, 2003 Should we take advantage of their uricosuric properties in clinical practice? The interesting study published in this issue of the journal by Takahashi et al sheds light on two drugs, losartan and fenofibrate, which have hypouricaemic properties, in addition to their main therapeutic effects.1 Losartan potassium is an orally active angiotensin II ...
openaire +2 more sources
Pharmaceutical Biology, 2018 Context: Ginkgo leaf tablets (GLTs) and losartan are often simultaneously used for the treatment of hypertension in Chinese clinics. However, the herb–drug interaction between GLT and losartan is still unknown.
Baiping Dong +3 more
doaj +1 more source
Comparison of Higher Dose of Losartan Treatment with Losartan Plus Carvedilol and Losartan Plus Ramipril in Patients with Glomerulonephritis and Proteinuria [PDF]
Renal Failure, 2007 Proteinuria may cause a worsening of accompanying renal disease or even lead to glomerulosclerosis. There is no data about the effect of carvedilol on patients with proteinuric (>0.5 g/day) glomerulonephritis. This study aimed to compare the effects of carvedilol with ramipril and losartan in patients with proteinuric glomerulonephritis.Twenty-one ...
Ersoy, ALPARSLAN +7 more
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Losartan-induced Pancreatitis [PDF]
Cureus, 2019 Drug-induced acute pancreatitis (DIAP) is a rare gastrointestinal condition but well-known in the medical literature. The medications have been classified into four subgroups (Classes I-IV) depending upon the propensity of the cases discussed in the literature, interval time period between drug initiation to pancreatitis, and reaction to the drug with ...
Rameez Shaukat +2 more
openaire +2 more sources
Contemporary Clinical Trials Communications, 2022 Objectives: To assess the efficacy and safety of losartan for COVID-19 patients. Methods: COVIDMED was a double-blinded, placebo-controlled platform RCT.
Daniel Freilich +3 more
doaj
Neuroprotective Effect of Losartan after Traumatic Brain Injury in Male Rats Based on Marmarou Model
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022 Background and Objective: Traumatic brain injury is the most important cause of death among young people in the world. Considering the neuroprotective effect of losartan on the recovery of brain damage, the present study was conducted to investigate the ...
Sh Shadi +2 more
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