Results 31 to 40 of about 28,228 (226)

Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma. [PDF]

PLoS ONE, 2015
PURPOSE:To determine if oral losartan treatment decreases the retinal ganglion cell (RGC) death caused by experimental intraocular pressure (IOP) elevation in mice.
Harry A Quigley, Ian F Pitha, Derek S Welsbie, Cathy Nguyen, Matthew R Steinhart, Thao D Nguyen, Mary Ellen Pease, Ericka N Oglesby, Cynthia A Berlinicke, Katherine L Mitchell, Jessica Kim, Joan J Jefferys, Elizabeth C Kimball   +12 more
doaj   +1 more source

Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan

Arquivos Brasileiros de Cardiologia, 2000
OBJECTIVE: To compare the regression of left ventricular hypertrophy in patients with moderate hypertension treated with enalapril, losartan or a combination of the two drugs at lower doses.
Antônio Carlos Avanza Jr, Lilian Mameri El Aouar, José Geraldo Mill   +2 more
doaj   +1 more source

CYTOCHROME P450 (CYP2C9) ACTIVENESS, EVALUATED VIA LOSARTAN TEST, AS PREDICTION MARKER FOR THE WARFARIN TREATMENT DOSAGE CHOICE IN PATIENTS WITH DELAYED OUTCOMES AFTER HEART VALVES REPLACEMENT

Российский кардиологический журнал, 2015
Aim. To evaluate the influence of gene СYP2C9 activeness via losartan test on the warfarin dosage management in earlier and long-term post-operational periods.Material and methods. Totally 33 patients included with artificial heart valves.
S. M. Arslanbekova, D. A. Sychev, K. B. Mirzaev, R. E. Kazakov, V. V. Smirnov, N. M. Magomedova, E. Z. Golukhova   +6 more
doaj   +1 more source

Machine learning approach to identify phenotypes in patients with ischaemic heart failure with reduced ejection fraction

European Journal of Heart Failure, EarlyView.
Summary of the machine learning clustering methodology and results of the study. Clusters are identified using machine learning approach in the learning set population evaluating specific combinations of multiple characteristics. Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes.
Luca Monzo, Emmanuel Bresso, Kenneth Dickstein, Bertram Pitt, John G.F. Cleland, Stefan D. Anker, Carolyn S.P. Lam, Mandeep R. Mehra, Dirk J. van Veldhuisen, Barry Greenberg, Faiez Zannad, Nicolas Girerd   +11 more
wiley   +1 more source

Degradation kinetics and characterization of degradation products of losartan potassium by LC-MS/MS method [PDF]

Arhiv za farmaciju, 2019
This paper presents study of losartan potassium stability evaluation by liquid chromatography with UV/VIS and MS-MS detection and its degradation profile. A solution of losartan potassium was exposed to the following stress agents: 0.1 M HCl, 0.1 M NaOH,
Dobričić Vladimir, Marković Bojan
doaj   +1 more source

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

ELECTROPHORESIS, EarlyView.
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley   +1 more source

Nephroprotective effect of losartan in IgA model rat

Journal of International Medical Research, 2019
Objective This study was performed to investigate the possible nephroprotective effects of losartan in a rat model of experimental IgA nephropathy (IgAN). Methods Thirty male Sprague–Dawley rats were randomly divided into three groups.
Li Xing, Er Lin Song, Xi Bei Jia, Jing Ma, Bing Li, Xu Gao   +5 more
doaj   +1 more source

Data on the effects of losartan on protein expression, vascular reactivity and antioxidant capacity in the aorta of ethanol-treated rats

Data in Brief, 2017
We describe the effects of losartan, a selective AT1 receptor antagonist on the alterations induced by treatment with ethanol in the rat aorta. The data shown here are related to the article entitled “Angiotensin type 1 receptor mediates chronic ethanol ...
Carla S. Ceron, Gabriel T. do Vale, Janaina A. Simplicio, Patrícia Passaglia, Sthefany T. Ricci, Carlos R. Tirapelli   +5 more
doaj   +1 more source

Losartan and magnesium sulfate administration reduce gentamicin-induced nephrotoxicity in rat model [PDF]

Journal of Nephropathology, 2019
Background: Nephrotoxicity is the most known side effect of gentamicin. In addition, renin angiotensin system (RAS) plays an important role in the pathogenesis of renal injury and nephrotoxicity.
Fatemeh Kourkinejad Gharaei, Tahereh Safari, Abbass Ali Niazi, Meysam Zeynali Bujani   +3 more
doaj   +1 more source

Lower time‐averaged serum uric acid was associated with increased mortality in peritoneal dialysis patients

Therapeutic Apheresis and Dialysis, EarlyView.
Abstract Background The relationship between time‐averaged serum uric acid (TA‐SUA) levels and prognosis in peritoneal dialysis (PD) patients are rarely discussed. Methods This was a retrospective cohort study. PD patients recruited from January 1, 2011, to December 31, 2020, were included.
Lu Li, Hongxia Zhang, Botao Zhang, Fangyuan Yang, Mengting Wang, Wenlong Qiu, Lina Fu, Menghua Chen, Na Tian   +8 more
wiley   +1 more source