Results 51 to 60 of about 28,228 (226)
The interplay between heart failure and chronic kidney disease
Diabetes, Obesity and Metabolism, EarlyView.Abstract Chronic kidney disease (CKD) and heart failure (HF) are two globally prevalent, independent, long‐term conditions, which often coexist in an individual and display a bidirectional yet interconnected relationship. The presence of CKD often leads to the development of HF and vice versa, which propagates the worsening of each disease, reflecting ...
Anuradha Lala +2 more
wiley +1 more source
Bone Reports, 2022 Background and aims: Previous work has shown that oral losartan can enhance microfracture-mediated cartilage repair in a rabbit osteochondral defect injury model.
Zhenhan Deng +8 more
doaj
Cardiology and Therapy, 2019 Introduction The role of losartan in preventing aortic root dilatation in Marfan syndrome has been evaluated in many clinical trials; however, the results are conflicting.
Ayman Elbadawi +12 more
doaj +1 more source
Internal Medicine Journal, EarlyView.Abstract Background Serum uric acid (SUA) has been associated with an increased risk of cardiovascular disease (CVD) in both the general population and individuals with type 2 diabetes (T2DM). Identification of high‐risk individuals is crucial for the primary prevention of CVD.
Funda Yildirim Borazan +3 more
wiley +1 more source
Journal of Orthopaedic Translation, 2021 Objective: Losartan and activation of the peroxisome proliferator-activated receptor-γ (PPARγ) have been previously reported to alleviate the progression of osteoarthritis (OA).
Zhenhan Deng, MD, Ph.D +6 more
doaj
Bibliometric Analysis of the 50 Most Cited Publications in Epidermolysis Bullosa
Pediatric Dermatology, EarlyView.ABSTRACT Epidermolysis bullosa (EB) is a group of inherited skin disorders characterized by extreme skin fragility, leading to recurrent blistering and significant impacts on patients' quality of life. A bibliometric analysis of the 50 most‐cited EB articles from the past six decades reveals that the majority of research focuses on understanding EB ...
Evelyn F. Fagan +4 more
wiley +1 more source
Journal of Applied Toxicology, Volume 45, Issue 5, Page 841-857, May 2025.ABSTRACT N‐Nitrosodimethylamine (NDMA) is a known water disinfection byproduct (DBP) characterized as a potent hepatotoxin, promutagen, and probable human carcinogen; this is because of the metabolites associated with its biotransformation. The metabolism of NDMA produces formaldehyde, another alkylating agent and DBP. Both compounds are generated from
Oscar Eduardo Tabares‐Mosquera +3 more
wiley +1 more source
Acta Physiologica, Volume 241, Issue 5, May 2025.Abstract Aim H+ facilitates metabolic blood flow regulation while negatively impacting cardiac contractility. Cardiovascular consequences of conjugate bases accumulating alongside H+ remain unclear. Here, we evaluate the cardiovascular effects of nine prominent carboxylates—particularly lactate, 3‐hydroxybutyrate, and butyrate—linked to metabolic and ...
Casper Homilius +5 more
wiley +1 more source
Losartan Enhances the Success of Myoblast Transplantation [PDF]
Cell Transplantation, 2012 Duchenne muscular dystrophy is a recessive X-linked genetic disease caused by dystrophin gene mutations. Cell therapy can be a potential approach aiming to introduce a functional dystrophin in the dystrophic patient myofibers. However, this strategy produced so far limited results.
Yann Lamarre +3 more
openaire +4 more sources
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease
Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.ABSTRACT Cerebral small vessel disease (cSVD) is a significant global health issue, accounting for approximately 25% of ischemic strokes and 20% of all dementia cases. CADASIL, the most common monogenic form of cSVD, is caused by stereotyped mutations in the NOTCH3 receptor that alter the number of cysteine residues in its extracellular domain ...
Anne Joutel
wiley +1 more source