Results 51 to 60 of about 73,633 (314)

Effects of losartan combined with exercise training in spontaneously hypertensive rats

Brazilian Journal of Medical and Biological Research, 2003
We investigate whether combined treatment with losartan, an angiotensin II receptor blocker, and exercise training (ET) in spontaneously hypertensive rats (SHR) would have an additive effect in reducing hypertension and improving baroreflex sensitivity ...
L.F. Azevedo, P.C. Brum, K.C. Mattos, C.M. Junqueira, M.U.P.B. Rondon, A.C.P. Barretto, C.E. Negrao   +6 more
doaj   +1 more source

Expert Approaches to the Assessment of Losartan Drugs Bioequivalence

Регуляторные исследования и экспертиза лекарственных средств, 2020
Angiotensin II receptor antagonists (ARAs) are one of the most promising classes of antihypertensive drugs. They are most widely represented on the Russian market by losartan drugs which total 24 items.
D. P. Romodanovsky, D. V. Goryachev
doaj   +1 more source

Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma. [PDF]

PLoS ONE, 2015
PURPOSE:To determine if oral losartan treatment decreases the retinal ganglion cell (RGC) death caused by experimental intraocular pressure (IOP) elevation in mice.
Harry A Quigley, Ian F Pitha, Derek S Welsbie, Cathy Nguyen, Matthew R Steinhart, Thao D Nguyen, Mary Ellen Pease, Ericka N Oglesby, Cynthia A Berlinicke, Katherine L Mitchell, Jessica Kim, Joan J Jefferys, Elizabeth C Kimball   +12 more
doaj   +1 more source

Relationship between antihypertensive medications and cognitive impairment: Part II. Review of Physiology and animal studies [PDF]

, 2016
Purpose of Review There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer’s disease; however, associations between antihypertensive medications (AHM) and dementia risk are
Carlson, MC, Peters, J, Peters, R, Schuchman, M, Yasar, S   +4 more
core   +1 more source

Changes to the gut microbiota induced by losartan contributes to its antihypertensive effects

British Journal of Pharmacology, 2019
Hypertension is associated with gut dysbiosis. Here we have evaluated the effects of the angiotensin receptor antagonist losartan on gut microbiota in spontaneously hypertensive rats (SHR) to assess their contribution to its antihypertensive effects.
Iñaki Robles-Vera, M. Toral, N. Visitación, Manuel Calderón Sánchez, M. Gómez-Guzmán, Raquel Muñoz, F. Algieri, T. Vezza, R. Jiménez, J. Gálvez, M. Romero, J. Redondo, J. Duarte   +12 more
semanticscholar   +1 more source

Different initiatives across Europe to enhance losartan utilisation post generics: impact and implications

Frontiers in Pharmacology, 2014
Introduction: There is an urgent need for health authorities across Europe to fully realise potential savings from increased use of generics to sustain their healthcare systems.
James eMoon, Brian eGodman, Brian eGodman, Max ePetzold, Samantha eAlvarez-Madrazo, Kathleen eBennett, Iain eBishop, Anna eBucsics, Ulrik eHesse, Andrew eMartin, Steven eSimoens, Corinne eZara, Rickard E Malmstrom   +12 more
doaj   +1 more source

Observational study of type of surgical training and outcome of definitive surgery for primary malignant melanoma [PDF]

, 2002
No abstract ...
Bray, C.A., Hole, D.J., Mackie, R.M.
core   +2 more sources

Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan

Arquivos Brasileiros de Cardiologia, 2000
OBJECTIVE: To compare the regression of left ventricular hypertrophy in patients with moderate hypertension treated with enalapril, losartan or a combination of the two drugs at lower doses.
Antônio Carlos Avanza Jr, Lilian Mameri El Aouar, José Geraldo Mill   +2 more
doaj   +1 more source

Angiotensin II-Type I Receptor Antagonism Does Not Influence the Chemoreceptor Reflex or Hypoxia-Induced Central Sleep Apnea in Men

Frontiers in Neuroscience, 2020
Components of the renin-angiotensin system (RAS) situated within the carotid body or central nervous system may promote hypoxia-induced chemoreceptor reflex sensitization or central sleep apnea (CSA).
Courtney V. Brown, Lindsey M. Boulet, Tyler D. Vermeulen, Scott A. Sands, Richard J. A. Wilson, Najib T. Ayas, Najib T. Ayas, John S. Floras, Glen E. Foster   +8 more
doaj   +1 more source

Pharmacological effects of raas blockade in ischemic nephropathy [PDF]

, 2016
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio, Cianci, Rosario, Coppolino, Giuseppe, Di Mario, Francesca, Farrah, Tariq E., Fuiano, Giorgio, Gigante, Antonietta, Rivoli, Laura, Rosato, Edoardo   +8 more
core   +1 more source