Results 11 to 20 of about 585,431 (288)

Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease [PDF]

, 2018
OBJECTIVE: To determine the percentage of children with nonalcoholic fatty liver disease (NAFLD) in whom intervention for low-density lipoprotein cholesterol or triglycerides was indicated based on National Heart, Lung, and Blood Institute guidelines.
Adina Alazraki, Ajay K. Jain, Alan Wells, Albert Hernandez, Alex Towbin, Ali Mencin, Alice Sternberg, Ann Klipsch, Ann Scheimann, April Carr, Averell Sherker, Bradley Aouizerat, Camille Langlois, Claude Sirlin, Craig Bross, Cynthia A. Behling, Cynthia Rigsby, Daniel Podberesky, David E. Kleiner, Debra King, Diana Lopez-Graham, Edward C. Doo, Elena Reynoso, Elizabeth M. Brunt, Emily Ragozzino, Emily Rothbaum Perito, Erin Hallinan, Evelyn Hsu, Gerald Behr, Girish Subbarao, Hannah Awai, James Tonascia, Janet Freebersyser, Janis Durelle, Jay H. Hoofnagle, Jay H. Lefkowitch, Jean P. Molleston, Jeanne M. Clark, Jeffrey B. Schwimmer, Jennifer Collins, Jesse Courtier, Jessica Cruz Munos, Jinping Lai, Joan Siegner, Joel E. Lavine, Jonathan A. Africa, Jose Derdoy, Joy Ito, Kara Cooper, Karen Murray, Katherine Yates, Kathleen Lake, Kathryn E. Harlow, Kathryn Fowler, Kevin P. May, Kim Cecil, Kimberlee Bernstein, Kimberly Kafka, Kimberly P. Newton, Kristin Bramlage, Kristina Wriston, Kumar Sandrasegaran, Laura Miriel, Laura Walker, Laura Wilson, Leanel Maldonado, Linda D. Ferrell, Lisa Sharda, Lixin Zhu, Maria Cordero, Mariana Dominguez Villarreal, Mark H. Fishbein, Mark Van Natta, Matthew Yeh, Melissa Paiz, Melissa Young, Michael Middleton, Michele Donithan, Milana Isaacson, Miriam B. Vos, Molly Bozic, Natasha Feier, Nicholas Raviele, Oscar W. Cummings, Pat Osmack, Patricia H. Belt, Patricia R. Robuck, Patricia Ugalde-Nicalo, Patrika Tsai, Peter F. Whitington, Philip Rosenthal, Rajesh Krisnamurthy, Randolph Otto, Rebecca Cleeton, Rebecca Torrance, Rohit Kohli, Rory Mahabir, Ryan Gill, Ryan Himes, Saeed Mohammad, Sarah Barlow, Sarah Barlow, Saul Karpen, Sherry Brown, Simon Horslen, Sonja Williams, Stavra A. Xanthakos, Stephanie DeVore, Stephanie H. Abrams, Susan S. Baker, Susan Stewart, Susan Torretta, Theresa Cattoor   +112 more
core   +2 more sources

Low-Density Lipoproteins Oxidation and Endometriosis [PDF]

Mediators of Inflammation, 2013
The etiopathogenesis of endometriosis still remains unknown. Recent data provide new valuable information concerning the role of oxidative stress in the pathophysiology of the disease. It has been proved that levels of different lipid peroxidation end products are increased in both peritoneal fluid (PF) and serum of endometriotic patients.
Grzegorz Polak, Bartłomiej Barczyński, Wojciech Kwaśniewski, Wiesława Bednarek, Iwona Wertel, Magdalena Derewianka-Polak, Jan Kotarski   +6 more
openaire   +3 more sources

Non-oxidative modification of native low-density lipoprotein by oxidized low-density lipoprotein [PDF]

Biochemical Journal, 1996
The oxidative modification of low-density lipoprotein (LDL) has been implicated in the pathogenesis of atherosclerosis, although little is known as yet about the precise mechanism of oxidation in vivo. The studies presented here demonstrate that, in the absence of cells or transition metals, oxidized LDL can modify native LDL through co-incubation in ...
M, Yang, D S, Leake, C A, Rice-Evans
openaire   +2 more sources

Low-Density Lipoprotein Receptors

, 1991
The origins of the receptor theory are based on the work of Paul Ehrlich (1854–1915) and John Newport Langley (1852–1925) (Parascandola 1981), who were the first to postulate that specific cellular reactions to drugs must be based on so-called receptive substances.
Niendorf, A., Beisiegel, Ulrike, Seifert, G.   +2 more
openaire   +3 more sources

Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]

, 2013
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A., Caslake, M.J., Cooney, J., Freeman, D.J., Griffin, B.A., Meyer, B.J., Nilsson, S., Olivecrona, G., Ramsay, J.E., Stewart, F.M.   +9 more
core   +2 more sources

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. [PDF]

, 2018
Large-scale deep-coverage whole-genome sequencing (WGS) is now feasible and offers potential advantages for locus discovery. We perform WGS in 16,324 participants from four ancestries at mean depth >29X and analyze genotypes with four quantitative ...
Abecasis, Goncalo, Alver, Maris, Bloom, Jonathan M, Chaffin, Mark, Correa, Adolfo, Cupples, L Adrienne, Engreitz, Jesse M, Ernst, Jason, Esko, Tonu, Ganna, Andrea, Johnson, W Craig, Kathiresan, Sekar, Kellis, Manolis, Khera, Amit V, Lander, Eric S, Manichaikul, Ani, Mitchell, Braxton, Montasser, May, Natarajan, Pradeep, Neale, Benjamin M, NHLBI TOPMed Lipids Working Group, O'Connell, Jeffrey R, Peloso, Gina M, Perry, James A, Poterba, Timothy, Rich, Stephen S, Ripatti, Samuli, Rotter, Jerome I, Ruotsalainen, Sanni E, Salomaa, Veikko, Seed, Cotton, Surakka, Ida L, Vasan, Ramachandran S, Willer, Cristen J, Wilson, James G, Zekavat, Seyedeh Maryam, Zhou, Wei   +36 more
core   +2 more sources

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin, Amento, Edward P, Kong, Raymond, Liu, David, Lundry, Jason, Madasamy, Shanmugavel, Robinson, J Paul, Wu, Alan HB   +7 more
core   +1 more source

Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]

, 2017
BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia, Bernini, Franco, Ferri, Nicola, Izzo, Raffaele, Marchiano, Silvia, Rozza, Francesco, Trimarco, Valentina, Zimetti, Francesca   +7 more
core   +3 more sources

Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice [PDF]

, 2006
OBJECTIVE - The role of cholesteryl ester transfer protein (CETP) in the development of atherosclerosis is still undergoing debate. Therefore, we evaluated the effect of human CETP expression on atherosclerosis in APOE*3-Leiden (E3L) mice with a ...
Dallinga-Thie, G.M. (Geesje), Haan, W. (Willeke) de, Havekes, L.M. (Louis), Hoogt, C.C. (Caroline) van der, Jukema, J.W. (Jan Wouter), Offerman, E. (Erik), Rensen, P.C.N. (Patrick), Westerterp, M. (Marit)   +7 more
core   +2 more sources

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source