Results 21 to 30 of about 34,716 (147)

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna, Kim, Kyoungmi, Litwin, Tomasz, Mazi, Tagreed A, Medici, Valentina, Sarode, Gaurav V, Shibata, Noreene M   +6 more
core   +2 more sources

Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice. [PDF]

PLoS ONE, 2014
Although increased serum histamine levels and H1R expression in the plaque are seen in atherosclerosis, it is not known whether H1R activation is a causative factor in the development of the disease, or is a host defense response to atherogenic signals ...
Vineesh V Raveendran, Donald D Smith, Xiaoyu Tan, Matthew E Sweeney, Gregory A Reed, Colleen A Flynn, Ossama W Tawfik, Ginger Milne, Kottarappat N Dileepan   +8 more
doaj   +1 more source

Perivascular mast cells regulate vein graft neointimal formation and remodeling [PDF]

, 2015
Objective. Emerging evidence suggests an important role for mast cells in vein graft failure. This study addressed the hypothesis that perivascular mast cells regulate in situ vascular inflammatory and proliferative responses and subsequent vein graft ...
Cambrook, Helen, Carberry, Jaclyn, Grassia, Gianluca, Ialenti, Armando, Kennedy, Simon, Lawrence, Catherine, MacRitchie, Neil, Maffia, Pasquale, Wadsworth, Roger M., Wu, Junxi   +9 more
core   +3 more sources

Yeast Products Mediated Ruminal Subenvironmental Microbiota, and Abnormal Metabolites and Digestive Enzymes Regulated Rumen Fermentation Function in Sheep

Animals, 2022
Yeast products (YP) are commonly used as rumen regulators, but their mechanisms of action are still unclear. Based on our previous studies, we questioned whether yeast products would have an impact on rumen solid-associated (SA) and liquid-associated (LA)
Manchun Su, Huihui Wang, Huibin Shi, Qiao Li, Yong Zhang, Taotao Li, Youji Ma   +6 more
doaj   +1 more source

Consensus on the Clinical Approach to Moderate-to-Severe Atopic Dermatitis in Spain: A Delphi Survey [PDF]

, 2020
Background. The purpose of this study was to gather information on the current assessment and management of patients with moderate-to-severe AD in routine daily practice. Methods.
Armario Hita, José Carlos, Baldrich, Esther Serra, Herráez, L., Jáuregui, Ignacio, Martín-Santiago, Ana, Ortiz de Frutos, Javier, Sastre, Joaquin, Silvestre, Juan Francisco, Universitat Autònoma de Barcelona, Valero, Antonio   +9 more
core   +3 more sources

Histamine activates inflammatory response and depresses casein synthesis in mammary gland of dairy cows during SARA

BMC Veterinary Research, 2018
Background Mounting evidences observed that subacute ruminal acidosis (SARA) induced by high concentration (HC) diet increases the translocation of histamine from digestive tract into circulation causing a diverse of diseases in dairy cows.
Guangjun Chang, Lailai Wang, Nana Ma, Wenwen Zhang, Huanmin Zhang, Hongyu Dai, Xiangzhen Shen   +6 more
doaj   +1 more source

Bioactive Amines in Wines. The Assessment of Quality Descriptors by Flow Injection Analysis with Tandem Mass Spectrometry

Molecules, 2022
Biogenic amines (BAs) occur in a wide variety of foodstuffs, mainly from the decomposition of proteins by the action of microorganisms. They are involved in several cellular functions but may become toxic when ingested in high amounts through the diet ...
Aina Mir-Cerdà, Javier Saurina, Sònia Sentellas   +2 more
doaj   +1 more source

Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian Hamster [PDF]

, 2009
Nonhibernating seasonal mammals have adapted to temporal changes in food availability through behavioral and physiological mechanisms to store food and energy during times of predictable plenty and conserve energy during predicted shortage.
Bamshad, Barrett, Barrett, Brown, C. K. Song, D. Spanswick, D. Wilson, Doi, Enriori, Franklin, Franklin, Garcia, Gottsch, Inagaki, J. G. Mercer, Jamali, Jamali, Leurs, Liu, M. van den Top, Malmlöf, Morgan, Morgan, Morton, Nakamura, Nilaweera, Ookuma, P. Barrett, P. J. Morgan, Panula, Pillot, Prendergast, Revel, Ross, Sakata, Sallmen, Sallmen, Schneider, Song, Spanswick, Spanswick, T. J. Bartness, Top, Tups, Viguié, Yoshimoto, Yoshimura   +46 more
core   +1 more source

Ketogenic diet protects MPTP‐induced mouse model of Parkinson's disease via altering gut microbiota and metabolites

MedComm, 2023
The ketogenic diet (KD) is a low‐carbohydrate, high‐fat regime that is protective against neurodegenerative diseases. However, the impact of KD on Parkinson's disease (PD) and its mechanisms remains unclear.
Ziying Jiang, Xinyu Wang, Haoqiang Zhang, Jian Yin, Peiqing Zhao, Qingqing Yin, Zhenfu Wang   +6 more
doaj   +1 more source

The intestinal lymphatic system: Functions and metabolic implications [PDF]

, 2019
The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Cifarelli, Vincenza, Eichmann, Anne
core   +2 more sources