Results 31 to 40 of about 605,029 (256)

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor

Journal of Lipid Research, 2005
Apolipoprotein E (apoE) associates with lipoproteins and mediates their interaction with members of the LDL receptor family. ApoE exists as three common isoforms that have important distinct functional and biological properties.
Jose Ruiz, Diana Kouiavskaia, Molly Migliorini, Susan Robinson, Evgueni L. Saenko, Natalia Gorlatova, Donghua Li, Daniel Lawrence, Bradley T. Hyman, Karl H. Weisgraber, Dudley K. Strickland   +10 more
doaj   +1 more source

The inconspicuous health benefit of blood donation

Global Journal of Transfusion Medicine, 2020
Background and Objectives: Regular blood donations seem to be beneficial to the health of donors in many ways. There is evidence to suggest that blood donation lowers blood viscosity and alters lipid profile, which is an acceptable parameter for ...
Alhaji Bukar, Erhabor Amos Tosan, Osita Simon Obi, Ajibola Sikiru Akinola, Gimba Waziri, Medugu Jessy Thomas, Aghatise Kevin, Christy Chinyere Fredrick, Osareniro Eguagie Osakue, Geogina Erifeta, Humphrey B Osadolor, Mathew Folaranmi Olaniyan   +11 more
doaj   +1 more source

Low-density lipoprotein particles in atherosclerosis

Frontiers in Physiology, 2022
Among the diseases causing human death, cardiovascular disease (CVD) remains number one according to the World Health Organization report in 2021. It is known that atherosclerosis is the pathological basis of CVD.
Ya-Nan Qiao, Yan-Li Zou, Shou-Dong Guo
doaj   +1 more source

Lipoprotein separation in a novel iodixanol density gradient, for composition, density, and phenotype analysis

Journal of Lipid Research, 2008
Separation of lipoproteins by traditional sequential salt density floatation is a prolonged process (∼72 h) with variable recovery, whereas iodixanol-based, self-generating density gradients provide a rapid (∼4 h) alternative.
Michael S. Yee, Darrell V. Pavitt, Tira Tan, Soundararajan Venkatesan, Ian F. Godsland, William Richmond, Desmond G. Johnston   +6 more
doaj   +1 more source

Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease [PDF]

, 2018
OBJECTIVE: To determine the percentage of children with nonalcoholic fatty liver disease (NAFLD) in whom intervention for low-density lipoprotein cholesterol or triglycerides was indicated based on National Heart, Lung, and Blood Institute guidelines.
Adina Alazraki, Ajay K. Jain, Alan Wells, Albert Hernandez, Alex Towbin, Ali Mencin, Alice Sternberg, Ann Klipsch, Ann Scheimann, April Carr, Averell Sherker, Bradley Aouizerat, Camille Langlois, Claude Sirlin, Craig Bross, Cynthia A. Behling, Cynthia Rigsby, Daniel Podberesky, David E. Kleiner, Debra King, Diana Lopez-Graham, Edward C. Doo, Elena Reynoso, Elizabeth M. Brunt, Emily Ragozzino, Emily Rothbaum Perito, Erin Hallinan, Evelyn Hsu, Gerald Behr, Girish Subbarao, Hannah Awai, James Tonascia, Janet Freebersyser, Janis Durelle, Jay H. Hoofnagle, Jay H. Lefkowitch, Jean P. Molleston, Jeanne M. Clark, Jeffrey B. Schwimmer, Jennifer Collins, Jesse Courtier, Jessica Cruz Munos, Jinping Lai, Joan Siegner, Joel E. Lavine, Jonathan A. Africa, Jose Derdoy, Joy Ito, Kara Cooper, Karen Murray, Katherine Yates, Kathleen Lake, Kathryn E. Harlow, Kathryn Fowler, Kevin P. May, Kim Cecil, Kimberlee Bernstein, Kimberly Kafka, Kimberly P. Newton, Kristin Bramlage, Kristina Wriston, Kumar Sandrasegaran, Laura Miriel, Laura Walker, Laura Wilson, Leanel Maldonado, Linda D. Ferrell, Lisa Sharda, Lixin Zhu, Maria Cordero, Mariana Dominguez Villarreal, Mark H. Fishbein, Mark Van Natta, Matthew Yeh, Melissa Paiz, Melissa Young, Michael Middleton, Michele Donithan, Milana Isaacson, Miriam B. Vos, Molly Bozic, Natasha Feier, Nicholas Raviele, Oscar W. Cummings, Pat Osmack, Patricia H. Belt, Patricia R. Robuck, Patricia Ugalde-Nicalo, Patrika Tsai, Peter F. Whitington, Philip Rosenthal, Rajesh Krisnamurthy, Randolph Otto, Rebecca Cleeton, Rebecca Torrance, Rohit Kohli, Rory Mahabir, Ryan Gill, Ryan Himes, Saeed Mohammad, Sarah Barlow, Sarah Barlow, Saul Karpen, Sherry Brown, Simon Horslen, Sonja Williams, Stavra A. Xanthakos, Stephanie DeVore, Stephanie H. Abrams, Susan S. Baker, Susan Stewart, Susan Torretta, Theresa Cattoor   +112 more
core   +2 more sources

Metabolic origins and clinical significance of LDL heterogeneity

Journal of Lipid Research, 2002
LDLs in humans comprise multiple distinct subspecies that differ in their metabolic behavior and pathologic roles. Metabolic turnover studies suggest that this heterogeneity results from multiple pathways, including catabolism of different VLDL and IDL ...
Kaspar K. Berneis, Ronald M. Krauss
doaj   +1 more source

The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis[S]

Journal of Lipid Research, 2015
Perlecan is a major heparan sulfate (HS) proteoglycan in the arterial wall. Previous studies have linked it to atherosclerosis. Perlecan contains a core protein and three HS side chains. Its core protein has five domains (DI–DV) with disparate structures
Yu-Xin Xu, David Ashline, Li Liu, Carlos Tassa, Stanley Y. Shaw, Katya Ravid, Matthew D. Layne, Vernon Reinhold, Phillips W. Robbins   +8 more
doaj   +1 more source

Low-Density Lipoproteins Oxidation and Endometriosis [PDF]

Mediators of Inflammation, 2013
The etiopathogenesis of endometriosis still remains unknown. Recent data provide new valuable information concerning the role of oxidative stress in the pathophysiology of the disease. It has been proved that levels of different lipid peroxidation end products are increased in both peritoneal fluid (PF) and serum of endometriotic patients.
Grzegorz Polak, Bartłomiej Barczyński, Wojciech Kwaśniewski, Wiesława Bednarek, Iwona Wertel, Magdalena Derewianka-Polak, Jan Kotarski   +6 more
openaire   +3 more sources

Beyond HDL-cholesterol increase: phospholipid enrichment and shift from HDL3 to HDL2 in alcohol consumers

Journal of Lipid Research, 2007
The reduction of cardiovascular mortality associated with moderate alcohol consumption is chiefly thought to be mediated by an increase of high density lipoprotein cholesterol (HDL-CH).
Christian Schäfer, Alexandr Parlesak, Joachim Eckoldt, Christiane Bode, Johann Christian Bode, Winfried März, Karl Winkler   +6 more
doaj   +1 more source

Low-Density Lipoprotein Receptors

, 1991
The origins of the receptor theory are based on the work of Paul Ehrlich (1854–1915) and John Newport Langley (1852–1925) (Parascandola 1981), who were the first to postulate that specific cellular reactions to drugs must be based on so-called receptive substances.
Niendorf, A., Beisiegel, Ulrike, Seifert, G.   +2 more
openaire   +3 more sources