Results 71 to 80 of about 323,060 (314)
The nature of pre beta (very low density) lipoproteins. [PDF]
R. I. Levy+2 more
openalex +1 more source
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac+7 more
wiley +1 more source
Naturally occurring mutant forms of apolipoprotein B (apoB)-100 may be able to provide valuable information on the structure-function relationships of apoB with the low density lipoprotein (LDL) receptor.
F.K. Welty, L. Seman, F.T. Yen
doaj
Identification and Genetic Control of Two New Low-Density Lipoprotein Allotypes: Phenogroups at the Lpq Locus [PDF]
John J. Albers, Sheldon Dray
openalex +1 more source
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen+2 more
wiley +1 more source
The oxidative modification of low density lipoproteins (LDL) by arterial wall cells is thought to contribute to atherogenesis. Monocyte/macrophages, among other arterial wall cells, oxidatively modify LDL to a form that is recognized by scavenger ...
R K Tangirala, M J Mol, D Steinberg
doaj
This study introduces a reliable technique for the large‐scale production of bacterial vesicles that maintain their immune‐modulating potential, enabling industrial manufacturing and clinical applications. Although other cancer immunotherapies are available, this research presents an advanced bacterial vesicle‐based therapeutic option, with scalable ...
Negar Ordouzadeh+6 more
wiley +1 more source
Phospholipid transfer protein (PLTP), hepatic lipase (HL), and lipoprotein lipase (LPL) have all been reported to be intricately involved in HDL metabolism but the effect of PLTP on the apolipoprotein B-containing lipoproteins relative to that of HL and ...
Susan J. Murdoch+4 more
doaj
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar+7 more
wiley +1 more source
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao+14 more
wiley +1 more source