Results 71 to 80 of about 1,617,704 (264)
Serum low density lipoprotein subclasses in asthma [PDF]
Background: The levels of serum low-density lipoproteins (LDL) have been implicated in the inflammatory cascade in a murine model of asthma. Recent findings suggest that LDL may modulate the inflammatory state of the asthmatic airways in humans ...
Bellia, V.+7 more
core +1 more source
High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice1[S]
The LDL receptor (LDLR) and scavenger receptor class B type I (SR-BI) play physiological roles in LDL and HDL metabolism in vivo. In this study, we explored HDL metabolism in LDLR-deficient mice in comparison with WT littermates.
Franz Rinninger+6 more
doaj
Self-Organization and Chaos in the Metabolism of Hemostasis in a Blood Vessel [PDF]
A mathematical model of the metabolic process of formation of the hemostasis in a blood-carrying vessel is constructed. As distinct from the earlier developed model of the multienzyme prostacyclin-thromboxane system of blood, this model includes, for the first time, the influence of the level of "bad cholesterol", i.e., low-density lipoproteins (LDLs),
arxiv +1 more source
The formation of cholesterol-loaded macrophage foam cells in arterial tissue may occur by the uptake of modified lipoproteins via the scavenger receptor pathway. The macrophage scavenger receptor, also called the acetylated low density lipoprotein (Ac-LDL) receptor, has been reported to recognize Ac-LDL as well as oxidized LDL species such as ...
Carl P. Sparrow+2 more
openaire +3 more sources
Combined data from LDL composition and size measurement are compatible with a discoid particle shape
The size of LDL is usually reported as particle diameter, with the implicit assumption that it is a spherical particle. On the other hand, data obtained by cryoelectron microscopy and crystallographic analysis suggest that LDL shape may be discoid.
Tom Teerlink+3 more
doaj
IMPORTANCE In clinical and research settings worldwide, low-density lipoprotein cholesterol (LDL-C) is typically estimated using the Friedewald equation.
S. Martin+6 more
semanticscholar +1 more source
Interactions of high density lipoproteins (HDL) with very low (VLDL) and low (LDL) density lipoproteins were investigated during in vitro lipolysis in the presence of limited free fatty acid acceptor. Previous studies had shown that lipid products accumulating on lipoproteins under these conditions promote the formation of physical complexes between ...
R M Krauss+2 more
openaire +4 more sources
Relationship between subclasses low-density lipoprotein and carotid plaque
Low-density lipoprotein (LDL) cholesterol can lead to the occurrence of atherosclerotic plaques, but patients with normal LDL still have atherosclerotic plaques in clinical practice.
Pan Zhanhai+6 more
doaj +1 more source
Low density lipoprotein undergoes oxidative modification in vivo.
It has been proposed that low density lipoprotein (LDL) must undergo oxidative modification before it can give rise to foam cells, the key component of the fatty streak lesion of atherosclerosis.
W. Palinski+9 more
semanticscholar +1 more source
NMR-based quantification of human lipoprotein (sub)classes is a powerful high-throughput method for medical diagnostics. We evaluated select proton NMR signals of serum lipoproteins for elucidating the physicochemical features and the absolute NMR ...
Daniela Baumstark+8 more
doaj