A Novel Hyaluronidase from Brown Spider (Loxosceles intermedia) Venom (Dietrich's Hyaluronidase): From Cloning to Functional Characterization [PDF]
, 2013 Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. the venom contains several enzymatic toxins.
Chaim, Olga Meiri +9 more
core +4 more sources
The Health Status of Horses Used for at Least Six Complete Cycles of Loxoscelic Antivenom Production
Toxins, 2023 Antivenom production against Loxosceles venom relies on horses being immunized and bled for plasma harvest. One horse can partake in several cycles of antivenom production, which will require years of constant venom and adjuvant inoculation and bleeding.
Ana Luísa Soares de Miranda +7 more
doaj +1 more source
The emerging field of venom-microbiomics for exploring venom as a microenvironment, and the corresponding Initiative for Venom Associated Microbes and Parasites (iVAMP) [PDF]
, 2019 Venom is a known source of novel antimicrobial natural products. The substantial, increasing number of these discoveries have unintentionally culminated in the misconception that venom and venom-producing glands are largely sterile environments.
Adams, Rachelle M.M. +13 more
core +1 more source
Journal of Venomous Animals and Toxins including Tropical Diseases, 2018 Background Loxoscelism is a severe human envenomation caused by Loxosceles spider venom. To the best of our knowledge, no study has evaluated the presence of antibodies against Loxosceles venom in loxoscelism patients without treatment with antivenom ...
Tomás Arán-Sekul +8 more
doaj +1 more source
Biotechnological potential of Phospholipase D for Loxosceles antivenom development [PDF]
, 2020 Loxoscelism is one of the most important forms of araneism in South America. The Health Authorities from countries with the highest incidence and longer history in registering loxoscelism cases indicate that specific antivenom should be administered ...
Cascone, Osvaldo +3 more
core +1 more source
Revista Brasileira em Promoção da Saúde, 2012 The loxoscelism is the most serious form of arachnidism in Brazil. The genus Loxosceles comprises more than 100 species of spiders in African and American continents. In Brazil, they are known as brown spiders.
Ricardo Marques Frezza
doaj +1 more source
Clinical complications of G6PD deficiency in Latin American and Caribbean populations : systematic review and implications for malaria elimination programmes [PDF]
, 2014 Background: Although G6PDd individuals are generally asymptomatic throughout their life, the clinical burden of this genetic condition includes a range of haematological conditions, including acute haemolytic anaemia (AHA), neonatal jaundice (NNJ) and ...
Bassat, Quique +9 more
core +2 more sources
Loxoscelism leading to penile necrosis
Revista da Sociedade Brasileira de Medicina Tropical, 2021 Gabriel Chahade Sibanto Simões +2 more
doaj +4 more sources
Autologous fibroblasts for the treatment of cutaneous loxoscelism: First experience
International Wound Journal, Volume 16, Issue 6, Page 1503-1505, December 2019., 2019 Abstract Several treatments have been described for cutaneous loxoscelism (CL), but the quality of available evidence is insufficient for the elaboration of a therapeutic consensus. Dapsone has shown beneficial effects on stopping the inflammatory phenomenon and accelerating the recovery. It is recommended to start dapsone once the visceral involvement
Antonio Guglielmetti +2 more
wiley +1 more source
Forty Years of the Description of Brown Spider Venom Phospholipases-D
Toxins, 2020 Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a serious public health issue, especially in regions of hot or temperate climates, such as parts of North and South America.
Luiza Helena Gremski +9 more
doaj +1 more source