Clinical Effects of the Immunization Protocol Using Loxosceles Venom in Naïve Horses [PDF]
Toxins, 2022 Bites of brown spiders (Loxosceles spp.) are responsible for dermonecrotic lesions and potentially systemic envenoming that can lead to death. The only effective therapy is the use of the antivenom, usually produced in horses.
Ana Luísa Soares de Miranda +7 more
doaj +3 more sources
Tetracycline Reduces Kidney Damage Induced by Loxosceles Spider Venom [PDF]
Toxins, 2017 Envenomation by Loxosceles spider can result in two clinical manifestations: cutaneous and systemic loxoscelism, the latter of which includes renal failure.
Rute Maria Gonçalves-De-Andrade +2 more
exaly +4 more sources
Venom from Loxosceles Spiders Collected in Southeastern and Northeastern Brazilian Regions Cause Hemotoxic Effects on Human Blood Components [PDF]
ToxinsSpiders of the genus Loxosceles represent a public health problem in Brazil due to the severity of the cutaneous and systemic effects that may result from their bite.
Rafaela Silva-Magalhães +10 more
doaj +3 more sources
Brown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes
Toxins, 2011 Venomous animals use their venoms as tools for defense or predation. These venoms are complex mixtures, mainly enriched of proteic toxins or peptides with several, and different, biological activities.
Fernando Matsubara +2 more
exaly +4 more sources
Predictive analysis of B-cell antigenic epitopes in phospholipase D toxins from Loxosceles spiders [PDF]
Toxicon: XThe Phospholipase D (PLD) toxin family, a major component of the Loxosceles spider venom, is a valuable biotechnological tool for developing antivenom treatment and diagnostic assays to overcome and prevent loxoscelism.
Alejandro Catalán +10 more
doaj +2 more sources
Renal Autotransplantation After Yang-Monti Neoureter Procedure: Surgical Case Report and Brief Literature Review. [PDF]
Case Rep UrolPurpose Ureteral strictures are a well‐documented pathology in urology, commonly resulting from congenital anomalies, iatrogenic injury, or other acquired conditions such as infection, trauma, or radiation. While ischemic and nonischemic strictures are recognized, bilateral idiopathic ureteral strictures remain rare, particularly when associated with ...
Anderson RM, Chang A, Baas W.
europepmc +2 more sources
Tetracycline reprograms inflammatory and regenerative signaling pathways in human keratinocytes exposed to Loxosceles spider venoms and sphingomyelinases [PDF]
Frontiers in PharmacologyIntroductionLoxosceles spider envenomation, or loxoscelism, constitutes the most severe form of araneism and frequently progresses to dermonecrosis with significant tissue damage.
Bruna Fernandes Pinto +6 more
doaj +2 more sources
Pyoderma gangrenosum and spider bites: a case series. [PDF]
J Dtsch Dermatol GesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 8, Page 997-999, August 2025.
Rapparini L +6 more
europepmc +2 more sources
Prospects and challenges of recombinant spider venom enzymes: insights from Loxosceles and Phoneutria venom protease expressions [PDF]
Frontiers in Bioengineering and BiotechnologySpiders use chemically complex venoms to overpower prey. Such venoms are primarily composed of neurotoxic disulfide-rich peptides, linear peptides, and enzymes.
Josephine Dresler +11 more
doaj +2 more sources
Structural and Energetic Evidence Supports the Non-Covalent Phosphate Cyclization by the Class II Phospholipase D from Loxosceles intermedia [PDF]
ToxinsPhospholipase D (PLD) enzymes from Loxosceles spider venom mediate envenomation pathology by cleaving phospholipid headgroups. We revisited the crystal structure of Loxosceles intermedia PLD (PDB: 3RLH) to evaluate two alternative mechanisms—covalent and
Carolina Gismene +5 more
doaj +2 more sources