Results 11 to 20 of about 33,152 (158)

Loxosceles gaucho venom-induced acute kidney injury--in vivo and in vitro studies. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
BACKGROUND: Accidents caused by Loxosceles spider may cause severe systemic reactions, including acute kidney injury (AKI). There are few experimental studies assessing Loxosceles venom effects on kidney function in vivo.
Rui V Lucato   +10 more
doaj   +3 more sources

Heterophilic antibodies in sera from individuals without loxoscelism cross-react with phospholipase D from the venom of Loxosceles and Sicarius spiders

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2018
Background Loxoscelism is a severe human envenomation caused by Loxosceles spider venom. To the best of our knowledge, no study has evaluated the presence of antibodies against Loxosceles venom in loxoscelism patients without treatment with antivenom ...
Tomás Arán-Sekul   +8 more
doaj   +3 more sources

Sphingomyelinase D from Loxosceles laeta Venom Induces the Expression of MMP7 in Human Keratinocytes: Contribution to Dermonecrosis. [PDF]

open access: yesPLoS ONE, 2016
Envenomation by Loxosceles spider is characterized by the development of dermonecrosis. In previous studies, we have demonstrated that increased expression/secretion of matrix metalloproteinases 2 and 9, induced by Loxosceles intermedia venom Class 2 ...
Mara A Corrêa   +4 more
doaj   +3 more sources

Effects of copaiba oil on dermonecrosis induced by Loxosceles intermedia venom

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2019
Background: Accidents caused by spiders of the genus Loxosceles constitute an important public health problem in Brazil. The venom of Loxosceles sp induces dermonecrosis at the bite site and systemic disease in severe cases. Traditional medicine based on
Mara Fernandes Ribeiro   +8 more
doaj   +2 more sources

Histopathological characterization of experimentally induced cutaneous loxoscelism in rabbits inoculated with Loxosceles similis venom [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2012
Envenomation by Loxosceles bites is characterized by dermonecrotic and/or systemic features that lead to several clinical signs and symptoms called loxoscelism. Dermonecrotic lesions are preceded by thrombosis of the dermal plexus.
NB Pereira   +9 more
doaj   +2 more sources

Design and Production of a Recombinant Hybrid Toxin to Raise Protective Antibodies against Loxosceles Spider Venom

open access: yesToxins, 2019
Human accidents with spiders of the genus Loxosceles are an important health problem affecting thousands of people worldwide. Patients evolve to severe local injuries and, in many cases, to systemic disturbances as acute renal failure, in which cases ...
Paula A. L. Calabria   +6 more
doaj   +2 more sources

Protective effects of mesenchymal stromal cell-derived secretome on dermonecrosis induced in rabbits by Loxosceles intermedia spider venom [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases
Background: Loxoscelism refers to a set of clinical manifestations caused by the bite of spiders from the Loxosceles genus. The classic clinical symptoms are characterized by an intense inflammatory reaction at the bite site followed by local necrosis ...
Gabriela Marques Rodrigues   +16 more
doaj   +2 more sources

Utilization of dapsone and hemoglobin in the epithelial skin regeneration therapy of cutaneous loxoscelism: A case report and integrative literature review [PDF]

open access: yesSão Paulo Medical Journal
BACKGROUND: Loxosceles spp are arthropods found worldwide. Its bite may produce cutaneous loxoscelism (necrotic or edematous) or cutaneous-visceral loxoscelism.
Omar Azuara-Antonio   +5 more
doaj   +2 more sources

Protective Effectiveness of an Immunization Protocol Against the Toxic Effects of Loxosceles intermedia Venom in Rabbits

open access: yesFrontiers in Veterinary Science, 2022
Loxosceles spp. (brown spiders) bites are responsible for the development of a syndrome consisting mainly of dermonecrotic lesions, and also systemic effects.
Ana Luísa Soares de Miranda   +7 more
doaj   +1 more source

Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): Spiders of the Loxosceles genus, known as violin spiders, produce venom with dermonecrotic and systemic effects, as it is a species widely distributed in the world, its study represents a high medical relevance.
Mireille Toledo-Blas   +9 more
doaj   +1 more source

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