Results 41 to 50 of about 33,152 (158)

Reciprocal transplantation of the heterotrophic coral Tubastraea coccinea (Scleractinia: Dendrophylliidae) between distinct habitats did not alter its venom toxin composition

Ecology and Evolution, Volume 10, Issue 4, Page 1794-1803, February 2020., 2020
Toxin complexity in the alien coral Tubastraea coccinea is conserved and co‐evolved with innovation of the venom delivery system. Morphological development of the coral and phenotypic expression of the venom and delivery system is not modulated by habitat pressures over short periods of time.
Marcelo V. Kitahara, Adrian Jaimes‐Becerra, Edgar Gamero‐Mora, Gabriel Padilla, Liam B. Doonan, Malcolm Ward, Antonio C. Marques, André C. Morandini, Paul F. Long   +8 more
wiley   +1 more source

Loxosceles deserta Spider Venom Induces the Expression of Vascular Endothelial Growth Factor (VEGF) in Keratinocytes [PDF]

, 2000
Evenomation by arachnids of the genus Loxosceles frequently results in disfiguring necrotic skin lesions. The cellular and molecular mechanisms which contribute to lesion development are incompletely defined but appear to involve participation of several
Warren, Jeffrey S., Desai, Anjali, Lankford, Heather A.   +2 more
core   +1 more source

Recombinant Protein Containing B-Cell Epitopes of Different Loxosceles Spider Toxins Generates Neutralizing Antibodies in Immunized Rabbits

Frontiers in Immunology, 2018
Loxoscelism is the most important form of araneism in South America. The treatment of these accidents uses heterologous antivenoms obtained from immunization of production animals with crude loxoscelic venom.
Sabrina de Almeida Lima, Clara Guerra-Duarte, Fernanda Costal-Oliveira, Thais Melo Mendes, Luís F. M. Figueiredo, Daysiane Oliveira, Ricardo A. Machado de Avila, Valéria Pereira Ferrer, Dilza Trevisan-Silva, Silvio S. Veiga, João C. Minozzo, Evanguedes Kalapothakis, Carlos Chávez-Olórtegui   +12 more
doaj   +1 more source

Toxicological Characterization and Phospholipase D Activity of the Venom of the Spider Sicarius thomisoides

Toxins, 2020
Envenomation by Loxosceles spiders (Sicariidae family) has been thoroughly documented. However, little is known about the potential toxicity of members from the Sicarius genus.
Tomás Arán-Sekul, Ivanka Perčić-Sarmiento, Verónica Valencia, Nelly Olivero, José M. Rojas, Jorge E. Araya, Andrés Taucare-Ríos, Alejandro Catalán   +7 more
doaj   +1 more source

Extracellular matrix molecules as targets for brown spider venom toxins

Brazilian Journal of Medical and Biological Research, 2001
Loxoscelism, the term used to describe lesions and clinical manifestations induced by brown spider's venom (Loxosceles genus), has attracted much attention over the last years. Brown spider bites have been reported to cause a local and acute inflammatory
S.S. Veiga, V.C. Zanetti, A. Braz, O.C. Mangili, W. Gremski   +4 more
doaj   +1 more source

Highlights in the knowledge of brown spider toxins

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematological abnormalities and impaired renal function.
Daniele Chaves-Moreira, Andrea Senff-Ribeiro, Ana Carolina Martins Wille, Luiza Helena Gremski, Olga Meiri Chaim, Silvio Sanches Veiga   +5 more
doaj   +1 more source

Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Loxosceles spiders’ venoms consist of a mixture of proteins, including the sphingomyelinases D (SMases D), which are the main toxic components responsible for local and systemic effects in human envenomation.
Priscila Hess Lopes, Mário T. Murakami, Fernanda C. V. Portaro, Kerly Fernanda Mesquita Pasqualoto, Carmen van den Berg, Denise V. Tambourgi   +5 more
doaj   +1 more source

Identification of a common epitope in knottins and phospholipases D present in Loxosceles sp venom by a monoclonal antibody

, 2023
International audienceIn the Americas and specially in Brazil, the Loxosceles intermedia, Loxosceles gaucho and Loxosceles laeta are the three most medically relevant brown spider species, and whose bites can lead to the condition known as loxoscelism ...
de Moura, Juliana, Aubrey, Nicolas, Machado-De-Ávila, Ricardo, Andrez, Alvarenga, Larissa, M, Alessandra Becker-Finco, Ricardo Andrez Machado-de-Ávila, Larissa M. Alvarenga, Billiald, Philippe, Camila Alves-Mondini, Isabella Gizzi Jiacomini, dos Santos Antunes, Nicolle, Martina Beltramino, Nicolas Aubrey, Becker-Finco, Alessandra, Beltramino, Martina, Sabrina Karim-Silva, Alves-Mondini, Camila, Jiacomini, Isabella, Gizzi, Nicolle dos Santos Antunes, Juliana de Moura, Karim-Silva, Sabrina, Philippe Billiald   +21 more
core   +1 more source

Anti-loxoscelic horse serum produced against a recombinant dermonecrotic protein of Brazilian Loxosceles intermedia spider neutralize lethal effects of Loxosceles laeta venom from Peru [PDF]

, 2015
In this work, an anti-loxoscelic serum was produced by immunizing horses with a recombinant dermonecrotic protein from Loxosceles intermedia (rLiD1). Anti-rLiD1 antibodies were able to recognize different species of Loxosceles venoms by Western Blot and ...
Yarleque, A., Bonilla, C., Tintaya, B., Chávez-Olórtegui, C., Machado de Avila, R.A., Duarte, C.G., Mendes, T.M., Guimarães, G., Silva, W.   +8 more
core   +1 more source

Methemoglobinemia associated with loxoscelism Meta-hemoglobinemia associada ao loxoscelismo

Revista do Instituto de Medicina Tropical de São Paulo, 1990
In twenty five patients who presented the cutaneous form of loxoscelism, serum haptoglobin and lactic dehydrogenase, erythrocyte glucose-6-phosphate dehydrogenase, glutathione reductase, glutathione peroxidase, methemoglobin, bilirubin and reticulocytes ...
Orlando C. de O. Barreto, Domingos M. de Cillo, Kimiyo Nonoyama, Luci C. Antonio, Pasquale Morena, João Luis C. Cardoso   +5 more
doaj   +1 more source