Defining the complex phenotype of severe systemic loxoscelism using a large electronic health record cohort. [PDF]
PLoS ONE, 2017 Systemic loxoscelism is a rare illness resulting from the bite of the recluse spider and, in its most severe form, can lead to widespread hemolysis, coagulopathy, and death.
Jamie R Robinson +5 more
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Clinical Spectrum of Hemolytic Anemia in Loxoscelism: Report of Two Cases Highlighting Variable Severity and Management [PDF]
Case Reports in HematologyLoxoscelism can cause local as well as systemic manifestations. Hematologic complications of brown recluse spider venom can be life-threatening.
Anas Al-Sadi +4 more
doaj +5 more sources
Systemic Loxoscelism, Less Frequent but More Deadly: The Involvement of Phospholipases D in the Pathophysiology of Envenomation [PDF]
Toxins, 2022 Bites of Loxosceles spiders can lead to a set of clinical manifestations called loxoscelism, and are considered a public health problem in many regions. The signs and symptoms of loxoscelism are divided into cutaneous and systemic forms.
Luiza Helena Gremski +7 more
doaj +3 more sources
Loxoscelism: Cutaneous and Hematologic Manifestations
Advances in Hematology, 2019 Background. Brown recluse spider (BRS) envenomation can lead to significant morbidity through severe local reaction and systemic illness including acute hemolytic anemia, rhabdomyolysis, disseminated intravascular coagulopathy (DIC), and even death.
Ngan Nguyen, Manjari Pandey
doaj +3 more sources
Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Spiders of the Loxosceles genus, known as violin spiders, produce venom with dermonecrotic and systemic effects, as it is a species widely distributed in the world, its study represents a high medical relevance.
Mireille Toledo-Blas +9 more
doaj +2 more sources
Systemic loxoscelism induced warm autoimmune hemolytic anemia: clinical series and review
Hematology, 2022 Objectives Describe the development of warm autoimmune hemolytic anemia warm (AIHA) secondary to a brown recluse spider (Loxosceles reclusa) bite is known as systemic loxoscelism; and review epidemiology, clinical manifestations, diagnostic work-up ...
Brandon Calhoun +3 more
doaj +3 more sources
Tetracycline reprograms inflammatory and regenerative signaling pathways in human keratinocytes exposed to Loxosceles spider venoms and sphingomyelinases [PDF]
Frontiers in PharmacologyIntroductionLoxosceles spider envenomation, or loxoscelism, constitutes the most severe form of araneism and frequently progresses to dermonecrosis with significant tissue damage.
Bruna Fernandes Pinto +6 more
doaj +2 more sources
Novel therapeutic approach for loxoscelism: efficacy of cefixime and netilmicin sulfate combination therapy [PDF]
Dermatology ReportsDear Editor, Loxoscelism, caused by bites from Loxosceles spiders, notably Loxosceles reclusa, presents with necrotic skin lesions and, in severe cases, systemic symptoms such as hemolysis, acute renal failure, and disseminated intravascular ...
Caterina Mariarosaria Giorgio +6 more
doaj +2 more sources
Utilization of dapsone and hemoglobin in the epithelial skin regeneration therapy of cutaneous loxoscelism: A case report and integrative literature review [PDF]
São Paulo Medical JournalBACKGROUND: Loxosceles spp are arthropods found worldwide. Its bite may produce cutaneous loxoscelism (necrotic or edematous) or cutaneous-visceral loxoscelism.
Omar Azuara-Antonio +5 more
doaj +2 more sources
Impact of antivenom administration on the evolution of cutaneous lesions in loxoscelism: A prospective observational study. [PDF]
PLoS Neglected Tropical Diseases, 2022 BackgroundSpiders of the genus Loxosceles are distributed throughout tropical and temperate regions worldwide. Loxosceles spp. bites may evolve to necrosis, with or without intravascular hemolysis.
Ceila M S Malaque +8 more
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