Results 31 to 40 of about 114,889,757 (218)

Lipoproteins in Cardiovascular Calcification: Potential Targets and Challenges

open access: yesFrontiers in Cardiovascular Medicine, 2018
Previously considered a degenerative process, cardiovascular calcification is now established as an active process that is regulated in several ways by lipids, phospholipids, and lipoproteins.
Yin Tintut   +6 more
doaj   +1 more source

Serum lipoprotein (a) and lipid profile in polycystic ovarian syndrome [PDF]

open access: yesJournal of Clinical and Scientific Research, 2015
Background: Polycystic ovarian syndrome (PCOS) is associated with dyslipidaemia and may render the affected women “at risk” of developing cardiovascular disease.
Swetha R, Ravi BV, Nalini KS
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Deficient perceptions and practices concerning elevated lipoprotein(a) among specialists in Singapore

open access: yesFrontiers in Cardiovascular Medicine
BackgroundMultiple guidelines recommend detection of and early risk factor management for elevated lipoprotein(a) [Lp(a)]. Effective implementation requires assessment of knowledge and practices regarding elevated Lp(a) among medical specialists.AimTo ...
Wann Jia Loh   +7 more
doaj   +1 more source

Lipoprotein(a) – Link between Atherogenesis and Thrombosis

open access: yesPrague Medical Report, 2019
Lipoprotein(a) – Lp(a) – is an independent risk factor for cardiovascular disease (CVD). Indeed, individuals with plasma concentrations of Lp(a) > 200 mg/l carry an increased risk of developing CVD. Circulating levels of Lp(a) are remarkably resistant to
Danica Labudovic   +5 more
doaj   +1 more source

Lipoprotein (a) predicts recurrent worse outcomes in type 2 diabetes mellitus patients with prior cardiovascular events: a prospective, observational cohort study

open access: yesCardiovascular Diabetology, 2020
Background Merging studies have reported the association of lipoprotein(a) [Lp(a)] with poor outcomes of coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM).
Yan Zhang   +11 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Clinical Profile of the Third Molar Predicting the Highest Risk of the Origin of Pericoronitis

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2005
The study was aimed to provide a simple profile of the third molar, which represents the highest risk for the origin of pericoronitis.The authors present the results of their own clinical investigation performed in patients who attended the Ward of Oral,
V. Schwartzová, D. Beluš, M. Kyseľ
doaj  

Decoding calcific aortic valve disease: superior predictive power of time-weighted lipoprotein(a)

open access: yesLipids in Health and Disease
Background Calcific aortic valve disease (CAVD) is a cardiovascular disease closely associated with aging. The role of lipoprotein(a) [Lp(a)] has attracted considerable attention in recent years.
Dan Jiang   +9 more
doaj   +1 more source

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