Results 41 to 50 of about 309,429 (287)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lipoprotein (a), as a vascular risk factor: current pharmacological therapies

, 2022
reservedL’aterosclerosi è una patologia ad eziologia multifattoriale che provoca grossi danni ai vasi arteriosi. Questi danni sono provocati da accumuli di grasso e colesterolo, detti placche ateromatose all’interno della parete arteriosa. Tali accumuli
MOROSIN, CORA
core  

On Lp-solvability of stochastic integro-differential equations [PDF]

, 2021
In this thesis, we investigate the Lp-solvability of a class of (possibly) degenerate stochastic integro-differential equations (SIDEs) of parabolic type, which includes the Zakai equation in nonlinear filtering for jump diffusions and the Kolmogorov ...
Wu, Sizhou
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Lp-functionals for change point detection in random coefficient autoregressive models

, 2023
We study a family of Lp-functionals of the weighted CUSUM test statistic to detect the presence of changepoints in the deterministic part of the autoregressive parameter in a Random Coefficient AutoRegressive sequence of order 1 (RCA(1)).
Horvath Lajos (15312355), Lorenzo Trapani (4172671)   +1 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Clinical Profile of the Third Molar Predicting the Highest Risk of the Origin of Pericoronitis

Česká Stomatologie a Praktické Zubní Lékařství, 2005
The study was aimed to provide a simple profile of the third molar, which represents the highest risk for the origin of pericoronitis.The authors present the results of their own clinical investigation performed in patients who attended the Ward of Oral,
V. Schwartzová, D. Beluš, M. Kyseľ
doaj  

Decoding calcific aortic valve disease: superior predictive power of time-weighted lipoprotein(a)

Lipids in Health and Disease
Background Calcific aortic valve disease (CAVD) is a cardiovascular disease closely associated with aging. The role of lipoprotein(a) [Lp(a)] has attracted considerable attention in recent years.
Dan Jiang, Yi-ling Liu, Jian Liu, Ping Wang, Jun-long Chen, Xue-song Wen, Jie Liu, Lei Gao, De-tao Li, Dong-ying Zhang   +9 more
doaj   +1 more source

Differential expression of Lp-PLA2 in obesity, type 2 diabetes and the influence of lipids [PDF]

, 2018
Aims/hypothesis Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a circulatory macrophage-derived factor that increases with obesity and leads to a higher risk of cardiovascular disease (CVD).
Moore, J.D., Jonathan D. Moore, Jackisch, Laura, Kyrou, Ioannis, Al-Daghri, N. M., Harpal Randeva, Barber, Thomas M., Warunee Kumsaiyai, Randeva, Harpal, Randeva, H., Al-Daghri, N, Moore, J.D, McTernan, P.G, McTernan, PG, Ioannis Kyrou, Sudhesh Kumar, Thomas M. Barber, Barber, TM, Barber, T.M, Al-Daghri, N., Tripathi, G, Jackisch, L, Kumsaiyai, W., Kumar, S., Al-Daghri, Nasser, Tripathi, G., Kumsaiyai, Warunee, McTernan, Philip G., Randeva, H, Laura Jackisch, Nasser Al-Daghri, Philip G. McTernan, Barber, T. M., Moore, Jonathan D., Gyanendra Tripathi, Kumsaiyai, W, Jackisch, L., Kumar, Sudhesh, Tripathi, Gyanendra, Kyrou, I, Randeva, Harpal S., McTernan, P. G., Kyrou, I., Kumar, S, McTernan, P.G., Moore, JD, Barber, T.M.   +46 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source