Results 211 to 220 of about 35,088 (264)

Cytosine base editing of LPA in transgenic mice averts large deletions. [PDF]

Mol Ther
Chuecos MA, Park SH, Bhakta MM, Too-Chiobi U, Betancourth D, Cao M, De Giorgi M, Walkey CJ, Tiwari A, Godin B, Assini JM, Palmer DJ, Ng P, Boffa MB, Koschinsky ML, Bao G, Lagor WR.   +16 more
europepmc   +1 more source

Asymptomatic Abnormalities in the Knee, Shoulder, and Ankle Joints of Collegiate Athletes: A Cross-Sectional MRI-Based Comparative Study. [PDF]

Diagnostics (Basel)
Jiang N, Wang H, Zhang X, Chen J, Wei G, Yan F, Li X, Lu Y.   +7 more
europepmc   +1 more source

Exploring the associations between physical activity, sleep, sedentary behaviour, and mental health in young German children. [PDF]

J Act Sedentary Sleep Behav
Osojnicki K, Brandes B, Brandes M, Zeeb H, Vallis LA, Buck C.   +5 more
europepmc   +1 more source

Correction to: Poster Session II - A258 THE ROLE OF BACTERIAL LPC AND LPA IN CHRONIC ABDOMINAL PAIN: A LONGITUDINAL STUDY IN PATIENTS WITH IBD. [PDF]

J Can Assoc Gastroenterol
europepmc   +1 more source

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LPA receptor 2 mediates LPA-induced endometrial cancer invasion

Gynecologic Oncology, 2009
We have previously shown that lysophosphatidic acid (LPA) promotes the ovarian cancer metastatic cascade. In this study, we evaluated the role of LPA on endometrial cancer invasion.Transient mRNA knockdown was accomplished using pre-designed siRNA duplexes against LPA receptor 2 (LPA2) and human matrix metalloproteinase-7 (MMP-7).
David A Fishman, Feng-Qiang Wang, Kara Long   +2 more
exaly   +3 more sources

LPA in neural cell development

Journal of Cellular Biochemistry, 2004
AbstractLysophosphatidic acid (LPA) elicits diverse cellular responses through cell surface LPA receptors in nervous system‐derived cells and cell lines. The developing nervous system is one of the major loci for LPA receptor expression. Recent studies have also revealed that metabolic pathways of LPA are present in the nervous system.
exaly   +3 more sources

The LPA receptors

Prostaglandins & Other Lipid Mediators, 2001
Lysophosphatidic acid (LPA) is a growth factor-like lipid that produces many cellular responses. These responses, including actin cytoskeletal rearrangements, cell proliferation and inhibition of gap junction communication, have been documented in many cell types over the last 2 decades.
N, Fukushima, J, Chun
openaire   +2 more sources

Tangier disease: isolation and characterization of LpA-I, LpA-II, LpA-I:A-II and LpA-IV particles from plasma

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1993
Tangier disease (TD) is characterized by extremely low plasma levels of HDL, apoA-I and apoA-II due to very rapid catabolism. However, the risk of premature coronary heart disease (CHD) is not markedly increased in TD. In order to gain insight into reverse cholesterol transport in TD, we isolated LpA-I, LpA-I:A-II, LpA-II and LpA-IV particles from ...
P, Duchateau, D, Rader, N, Duverger, N, Theret, C, De Geitere, H B, Brewer, J C, Fruchart, G R, Castro   +7 more
openaire   +2 more sources

Biology of LPA in health and disease

Seminars in Cell & Developmental Biology, 2004
The functions of lysophosphatidic acid (LPA) can be broadly divided into two classes: (1) physiological and (2) pathological roles. The role of LPA in embryonic development can be seen as early as oocyte formation. It continues in postnatal homeostasis, through its ability to impart a level of protection from both stress and local injury, by regulating
Saubhik, Sengupta, Zeneng, Wang, Russell, Tipps, Yan, Xu   +3 more
openaire   +2 more sources

LPA modulates monocyte migration directly and via LPA-stimulated endothelial cells

American Journal of Physiology-Cell Physiology, 2008
Lysophosphatidic acid (LPA) is a bioactive lysophospholipid ligand present in oxidized low-density lipoprotein. The effects of LPA were investigated, first separately on endothelial cells (EC) and monocytes. Using Ki16425 (an LPA1 and LPA3 receptor antagonist), GW9662 [a peroxisome proliferator-activator receptor (PPARγ) antagonist], and pertussis ...
Gustin, Cindy, Van Steenbrugge, Martine, Raes, Martine   +2 more
openaire   +3 more sources