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LPA and its Analogs-Attractive Tools for Elucidation of LPA Biology and Drug Development
Current Medicinal Chemistry, 2008Lysophosphatidic acid (LPA, 1- or 2-acyl-sn-glycerol 3-phosphate) is a simple phospholipid but displays an intriguing cell biology that is mediated via interactions with both G-protein-coupled seven transmembrane receptors (GPCRs) and nuclear hormone receptors.
Kuniyuki, Kano +3 more
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Mitogenic action of LPA in prostate
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002The lipid growth factor lysophosphatidic acid (LPA) elicits multiple cellular responses, including cell growth and survival. LPA acts upon target cells by activating its cognate receptors, which belong to the G protein-coupled endothelial differentiation gene (EDG) family.
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On the LPA model with $\mu_a$ = 1
Sarajevo Journal of MathematicsIn this article we establish conditions for the local stability of the positive fixed point for the structured population model of Dennis, Desharnais, Cushing, and Costantino (or LPA model) where no adults survive longer than a single time step and when there is a specific one-parameter bifurcation.
Jamieson, William T., Merino, Orlando
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DKS Reconstruction and LPA Size
The Annals of Thoracic Surgery, 2023Dominic, Emerson +2 more
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Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development
European Journal of Medicinal Chemistry, 2021Gurubasavaraj Pujar +2 more
exaly
Lysophosphatidic acid (LPA) receptors: Signaling properties and disease relevance
Prostaglandins and Other Lipid Mediators, 2010Deron Herr, Jerold Chun
exaly