Results 81 to 90 of about 35,088 (264)

Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells

Journal of Lipid Research, 2003
Lysophosphatidic acid (LPA) is a receptor-active lipid mediator with a broad range of biological effects. Ovarian cancer cells synthesize LPA, which promotes their motility, growth, and survival.
Céline Luquain, Anurag Singh, Lixin Wang, Vishwanathan Natarajan, Andrew J. Morris   +4 more
doaj   +1 more source

Eating Behavior Latent Profiles and Their Associations With Body Composition in Early Childhood: The CORALS Cohort

Obesity, EarlyView.
ABSTRACT Objective This study aimed to identify sex‐specific eating behavior profiles and assess the associations between eating behaviors subscales and profiles and body composition indices in Spanish preschoolers from the CORALS cohort. Methods We conducted a cross‐sectional analysis of baseline data from 1208 children aged 3–6 years (50.1% girls ...
Andrea Jimeno‐Martínez, María L. Miguel‐Berges, Ivie Maneschy, Mercedes Gil‐Campos, Rosaura Leis, Nancy Babio, Pilar De Miguel‐Etayo, Santiago Navas‐Carretero, Olga Portolés, Montserrat Fitó Colomer, Cristina Castro‐Collado, Rosaura Picáns‐Leis, Natalia Farré, Miguel Seral‐Cortés, J. Alfredo Martínez, José Jurado‐Castro, Rocío Vázquez‐Cobela, Cristina Rey‐Reñones, Belén Pastor‐Villaescusa, Francisco Llorente‐Cantarero, Karla‐Alejandra Pérez‐Vega, Jordi Salas‐Salvadó, Luis A. Moreno, Guiomar Masip, on behalf of CORALS group   +24 more
wiley   +1 more source

Gender effects on the distribution of the cholesteryl ester transfer protein in apolipoprotein A-I-defined lipoprotein subpopulations.

Journal of Lipid Research, 1994
Two subpopulations of apolipoprotein A-I-containing lipoproteins, those containing only apoA-I (LpA-I) and those containing both apoA-I and apoA-II (LpA-I/A-II), were isolated by immunoaffinity chromatography of plasma from 44 subjects, comprising four ...
P Moulin, M C Cheung, C Bruce, S Zhong, T Cocke, H Richardson, A R Tall   +6 more
doaj   +1 more source

3D‐Printed Crosslinked Nanocellulose‐MXene Hydrogels and Aerogels with High Strength and Conductivity

Small, EarlyView.
This study presents a robust strategy for 3D printing conductive, mechanically resilient MXene–CNF composite structures using a single‐step freeze‐induced crosslinking method. The printed architectures remain stable in both wet and dry states, exhibit high electrical conductivity and mechanical strength, and demonstrate practical application in fully ...
Nuzhet Inci Kilic, Kyle Matthews, Giovanni Marco Saladino, Yury Gogotsi, Per A. Larsson, Mahiar Max Hamedi   +5 more
wiley   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Gender‐Sensitive Resilience in Kyrgyz Households: Latent Profile and Cross‐Lagged Dynamic Panel Approaches

Australian Journal of Agricultural and Resource Economics, EarlyView.
ABSTRACT Resilience is still conceptualised as gender‐neutral in research and policy discussions. However, a gendered resilience framework suggests that gender roles and intra‐household dynamics are intricately linked with household resilience. This manuscript aims to analyse the effect of gender role attitudes on climate change resilience.
Bekhzod Egamberdiev, Lena Kuhn, Ihtiyor Bobojonov, Thomas Glauben   +3 more
wiley   +1 more source

Autotaxin and LPA receptors represent potential molecular targets for the radiosensitization of murine glioma through effects on tumor vasculature.

PLoS ONE, 2011
Despite wide margins and high dose irradiation, unresectable malignant glioma (MG) is less responsive to radiation and is uniformly fatal. We previously found that cytosolic phospholipase A2 (cPLA(2)) is a molecular target for radiosensitizing cancer ...
Stephen M Schleicher, Dinesh K Thotala, Amanda G Linkous, Rong Hu, Kathleen M Leahy, Eugenia M Yazlovitskaya, Dennis E Hallahan   +6 more
doaj   +1 more source

Translational research on autotaxin-LPA-LPA receptors and drug discovery

Clinical Lipidology, 2015
The discovery that lysophosphatidic acid (LPA) acts as a signaling molecule via its G protein-coupled receptors motivated studies on the signaling and pathophysiology of LPA. Furthermore, the subsequent identification of the LPA-producing plasma phosphodiesterase, autotaxin, led to structural and mouse genetic studies of this lysophospholipase D ...
openaire   +1 more source

Building in the Right Places: Can Labour Build Two Million New Homes?

The Political Quarterly, EarlyView.
Abstract Britain's housing crisis reflects not only insufficient supply but also the persistent tendency of new homes to be delivered in suboptimal locations. Even where excess demand is most acute—typically in the cores and fringes of major cities—planning constraints, political pressures and land‐use designations often limit development, while ...
Nikhil Datta, Amrita Kulka
wiley   +1 more source

HOUSING RETROFIT AND THE JUST TRANSITION IN THE METROPOLIS: Governance, Redistribution, and Inequality in London and Barcelona

International Journal of Urban and Regional Research, EarlyView.
Abstract Metropolises are rapidly becoming spaces of stark inequalities. While much literature has emphasized the metropolitan scale as a driver of agglomeration economies, recent scholarship highlights either the ungovernable nature of large metropolises or the weak redistributive capacity of their governments as key causes of increasingly unequal ...
Lucía Cerrada Morato, Marc Martí‐Costa, Cecilia Conde López   +2 more
wiley   +1 more source