Results 71 to 80 of about 35,088 (264)

Involvement of LPA Receptor 3 in LPA-induced BGC-803 Cell Migration

Mongolian Journal of Biological Sciences, 2013
Lysophosphatidic acid ˄ LPA ˅ is a bioactive phospholipid mediator, which elicits a variety of biological functions mainly through G-protein coupled receptors. Although LPA is shown to stimulate proliferation and motility via LPA receptors, LPAR1 and LPAR3 in several cancer cell lines, but the role of LPA receptors in gastric cancer cells is still ...
Erdene Oyungerel, Tserennadmid Tseveensuren, Oyun Gansukh, Li Rui Juan, Alatangaole Damirin   +4 more
openaire   +2 more sources

Are All “Good” Employees Susceptible to Moral Biases? Exceptional (Versus Intermediate) Moral Character Shapes Resilience to Daily “DIAMONDS” Situations That Trigger Moral Disengagement

Journal of Organizational Behavior, EarlyView.
ABSTRACT The non‐rationalist view of morality holds that all employees—including “good” apples—are liable to do bad because they are susceptible to moral biases in everyday situational encounters. In contrast, the rationalist or trait view suggests that employees with strong moral character should be resilient against moral biases across situations and
Babatunde Ogunfowora, Varun Sharma, Mohammad Khalilinejad, Kimberly Weston Moore   +3 more
wiley   +1 more source

Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines

Journal of Lipid Research, 2005
It is generally thought that the large heterogeneity of human HDL confers antiatherogenic properties; however, the mechanisms governing HDL biogenesis and speciation are complex and poorly understood.
Larbi Krimbou, Houssein Hajj Hassan, Sacha Blain, Shirya Rashid, Maxime Denis, Michel Marcil, Jacques Genest   +6 more
doaj   +1 more source

Exploring stressor exposure and mental health symptom patterns among forcibly displaced people: A latent profile analysis

Journal of Traumatic Stress, EarlyView.
Abstract The association between trauma exposure and mental health among forcibly displaced people (FDP) is well‐documented. However, prior research has largely employed variable‐centered approaches, which may obscure heterogeneity in individual experiences.
Lisa Dasen, Jennifer Kurath, Béatrice Strock, Karl Juri Weinreich, Julia Spaaij, Matthis Schick, Angela Nickerson, Richard A. Bryant, Naser Morina   +8 more
wiley   +1 more source

Second ACL injuries in football players after ACL reconstruction: A systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To determine the incidence of second anterior cruciate ligament (ACL) injuries in football players after index ACL reconstruction (ACLR). Secondary objectives were to assess second ACL injury rates across subgroups (laterality, sex, age, playing level, graft type, return to play [RTP] and follow‐up duration) and to review factors ...
Adolfo López Personat, Gonzalo Mariscal, Anders Stålman, Riccardo Cristiani, Christoffer Von Essen, Bruno Capurro‐Soler, Jorge Chahla, Alexander Sandon   +7 more
wiley   +1 more source

LPA₃: Pharmacodynamic Differences Between Lysophosphatidic Acid and Oleoyl-Methoxy Glycerophosphothionate: Biased Agonism, Two Sites

Receptors
Background: Lysophosphatidic acid (LPA) receptor 3 (LPA3) is involved in many physiological and pathophysiological actions of this bioactive lipid, particularly in cancer.
K. Helivier Solís, M. Teresa Romero-Ávila, Ruth Rincón-Heredia, Juan Carlos Martínez-Morales, J. Adolfo García-Sáinz   +4 more
doaj   +1 more source

Convergent Regulation of Neuronal Differentiation and Erk and Akt Kinases in Human Neural Progenitor Cells by Lysophosphatidic Acid, Sphingosine 1-Phosphate, and LIF: Specific Roles for the LPA1 Receptor

ASN Neuro, 2014
The bioactive lysophospholipids lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have diverse effects on the developing nervous system and neural progenitors, but the molecular basis for their pleiotropic effects is poorly understood.
Phillip Callihan, Mourad W. Ali, Hector Salazar, Nhat Quach, Xian Wu, Steven L. Stice, Shelley B. Hooks   +6 more
doaj   +1 more source

Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice

Journal of Lipid Research, 2013
Lysophosphatidic acid (LPA) is a bioactive lipid mediator. Concentrations of the major LPA species in mouse plasma decreased uniformly following administration of a potent selective inhibitor of the LPA-generating lysophospholipase D autotaxin ...
Abdel K. Salous, Manikandan Panchatcharam, Manjula Sunkara, Paul Mueller, Anping Dong, Yuhuan Wang, Gregory A. Graf, Susan S. Smyth, Andrew J. Morris   +8 more
doaj   +1 more source

Unicompartmental knee arthroplasty is associated with greater patient preference but higher revision rates than total knee arthroplasty in the same patient: A systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Despite the high prevalence of isolated knee compartment disease, unicompartmental knee arthroplasty (UKA) is often avoided in patients with a contralateral total knee arthroplasty (TKA). The present study aimed to evaluate the impact of a contralateral TKA on functional outcomes, patient preference and long‐term survivorship following
Randa Elsheikh, Nina Burgert, Arthur Kievit, Peter A. J. de Leeuw, Michael T. Hirschmann, Jari Dahmen   +5 more
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source