Results 61 to 70 of about 98,340 (281)

In vivo metabolism of apolipoprotein A-I on high density lipoprotein particles LpA-I and LpA-I,A-II.

Journal of Lipid Research, 1991
Apolipoprotein (apo) A-I is the major protein in high density lipoproteins (HDL) and is found in two major subclasses of lipoproteins, those containing apolipoprotein A-II (termed LpA-I,A-II) and those without apoA-II (termed LpA-I). The in vivo kinetics
DJ Rader, G Castro, LA Zech, JC Fruchart, HB Brewer, Jr   +4 more
doaj   +1 more source

Local Edge Betweenness based Label Propagation for Community Detection in Complex Networks

, 2017
Nowadays, identification and detection community structures in complex networks is an important factor in extracting useful information from networks.
Bagheri, Alireza, Shahrivari, Hamid
core   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor.

PLoS ONE, 2011
Lysophosphatidic acid (LPA), a lipid mediator enriched in serum, stimulates cell migration, proliferation and other functions in many cell types. LPA acts on six known G protein-coupled receptors, termed LPA(1-6), showing both overlapping and distinct ...
Maikel Jongsma, Elisa Matas-Rico, Adrian Rzadkowski, Kees Jalink, Wouter H Moolenaar   +4 more
doaj   +1 more source

Lysophosphatidic Acid Receptor 5 Contributes to Imiquimod-Induced Psoriasis-Like Lesions through NLRP3 Inflammasome Activation in Macrophages

Cells, 2020
The pathogenesis of psoriasis, an immune-mediated chronic skin barrier disease, is not fully understood yet. Here, we identified lysophosphatidic acid (LPA) receptor 5 (LPA5)-mediated signaling as a novel pathogenic factor in psoriasis using an imiquimod-
Bhakta Prasad Gaire, Chi-Ho Lee, Wondong Kim, Arjun Sapkota, Do Yup Lee, Ji Woong Choi   +5 more
doaj   +1 more source

Functional renormalization group with a compactly supported smooth regulator function

, 2013
The functional renormalization group equation with a compactly supported smooth (CSS) regulator function is considered. It is demonstrated that in an appropriate limit the CSS regulator recovers the optimized one and it has derivatives of all orders. The
A Rácz, C Bervillier, C Bervillier, C Wetterich, C Wetterich, CS Fischer, DF Litim, DF Litim, DF Litim, DF Litim, DF Litim, DF Litim, F Freire, FJ Wegner, I Nándori, I Nándori, I Nándori, I. Nándori, J Alexandre, J Alexandre, J Darai, J Polchinski, JI Latorre, JM Pawlowski, K-I Aoki, L Canet, L Canet, L Canet, O Lauscher, O Lauscher, OJ Rosten, P Salamon, P Salamon, RD Ball, S Nagy, S Nagy, S Nagy, S Nagy, S-B Liao, TM Byrnes, TR Morris   +40 more
core   +1 more source

Ductaler Abgang der LPA – erfolgreiche Rekrutierung der LPA durch 2-Stufenkonzept

, 2015
Der ductale Abgang einer Pulmonalarterie führt nach neonatalem Verschluss des Ductus zu einer fehlenden Perfusion der betreffenden Pulmonalarterie. Bei Kindern ohne zusätzliche kardiovaskuläre Fehlbildungen (z.B. Fallout Tetralogie, VSD) bleibt dies klinisch meist unbemerkt, die Patienten[for full text, please go to the a.m. URL]
Wiegand, G, Sieverding, L, Froese, G, Schlensak, C, Hofbeck, M   +4 more
openaire   +1 more source

Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA‐binding proteins in activation of LPA receptors [PDF]

FEBS Letters, 2002
Lysophosphatidic acid (LPA) exerts multiple biological functions through G protein‐coupled receptors (EDG2/LPA1, EDG4/LPA2, and EDG7/LPA3) and is present in serum where it is associated with albumin. In this study we examined LPA activity in various biological fluids by measuring the LPA‐induced increase in the intracellular concentration of calcium ...
Hama, Kotaro, Bandoh, Koji, Kakehi, Yoshiyuki, Aoki, Junken, Arai, Hiroyuki   +4 more
openaire   +2 more sources

Association Between Healthy Lifestyle Behaviors and Mental Health Symptoms in Children With Autism and ADHD: A Latent Profile Analysis

Autism Research, EarlyView.
ABSTRACT Healthy lifestyle behaviors, including physical activity, screen time, sleep, and diet quality, are important determinants of mental health, yet little is known about how these behaviors cluster among children with neurodevelopmental disorders.
Matthew Bourke, Jacqueline L. Walker, George Thomas, Kathryn Fortnum, Martin O'Flaherty   +4 more
wiley   +1 more source

Lysophosphatidic acid induces integrin activation in vascular smooth muscle and alters arteriolar myogenic vasoconstriction

Frontiers in Physiology, 2014
In vascular smooth muscle cells (VSMC) increased integrin adhesion to extracellular matrix (ECM) proteins, as well as the production of reactive oxygen species (ROS) are strongly stimulated by lysophosphatidic acid (LPA). We hypothesized that LPA-induced
Marius C. Staiculescu, Francisco I. Ramirez-Perez, Francisco I. Ramirez-Perez, Jorge A. Castorena-Gonzalez, Jorge A. Castorena-Gonzalez, Zhongkui eHong, Zhe eSun, Gerald A. Meininger, Gerald A. Meininger, Gerald A. Meininger, Luis A. Martinez-Lemus, Luis A. Martinez-Lemus, Luis A. Martinez-Lemus   +12 more
doaj   +1 more source