BMC Neuroscience, 2008 Background Lysophospholipids regulate the morphology and growth of neurons, neural cell lines, and neural progenitors. A stable human neural progenitor cell line is not currently available in which to study the role of lysophospholipids in human neural ...
Callihan Phillip +6 more
doaj +1 more source
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. [PDF]
, 2000 Acting through a number of distinct pathways, many G protein-coupled receptors (GPCRs) activate the extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) cascade.
Daaka, Y +4 more
core
Potassium channels of the K2P-family control the activity of neuronal cells - TRESK as regulator of inflammatory hyperalgesia [PDF]
, 2015 Das Empfinden von Schmerz ist für uns überlebenswichtig. Chronischer Schmerz hingegen hat seine physiologische Bedeutung verloren und wird als eigenes Krankheitsbild angesehen. Schmerzempfindung beginnt mit der Nozizeption.
Kollert, Sina
core
Lysophospholipid (LPA) receptors in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITELysophosphatidic acid (LPA) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Lysophospholipid Receptors [67, 27, 96, 151]) are activated by the endogenous phospholipid LPA. The first receptor, LPA1, was identified as ventricular zone gene-1 (vzg-1) [52], This discovery represented the beginning of the de-orphanisation of members of ...
Victoria Blaho +5 more
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Renal Cyst Fluid From Human Polycystic Kidney Disease Patients Stimulates Cl- Transport: Active Factor and Cl- Channels [PDF]
, 2011 poster abstractAutosomal dominant polycystic kidney disease (ADPKD) is characterized by the slow growth of fluid-filled cysts predominately in the kidney and in liver bile ducts.
Bacallao, Robert L. +3 more
core
The Emerging Role of LPA as an Oncometabolite
CellsLysophosphatidic acid (LPA) is a phospholipid that displays potent signalling activities that are regulated in both an autocrine and paracrine manner.
Theodoros Karalis, George Poulogiannis
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Frontiers in Bioscience-LandmarkLysophosphatidic acid (LPA), a bioactive lipid molecule, has been identified as a critical regulator of several cellular processes in the central nervous system, with significant impacts on neuronal function, synaptic plasticity, and neuroinflammatory ...
Simona Dedoni +3 more
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Uncovering unique roles of LPA receptors in the tumor microenvironment. [PDF]
Receptors Clin Investig, 2015 Lee SC, Fujiwara Y, Tigyi GJ.
europepmc +1 more source
LPA Induces Erythropoiesis Process Through Activating LPA Receptor 3
The FASEB Journal, 2011 Chi‐ling Chiang +4 more
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Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13 [PDF]
, 2017 Blumer, Kendall J +4 more
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