Results 101 to 110 of about 4,566 (176)

The combination of tumor mutational burden and T‐cell receptor repertoire predicts the response to immunotherapy in patients with advanced non–small cell lung cancer

MedComm
Tumor mutational burden (TMB) and T‐cell receptor (TCR) might predict the response to immunotherapy in patients with non–small cell lung cancer (NSCLC). However, the predictive value of the combination of TMB and TCR was not clear.
Yalun Li, Liyan Ji, Yingqian Zhang, Jiexin Zhang, Alexandre Reuben, Hao Zeng, Qin Huang, Qi Wei, Sihan Tan, Xuefeng Xia, Weimin Li, Jianjun Zhang, Panwen Tian   +12 more
doaj   +1 more source

Striking differences of LDL receptor-related protein 1B expression in mouse and human

, 2005
The low density lipoprotein (LDL) receptor-related protein 1B (LRP1B) is a member of the expanding LDL receptor family, and is closely related to LRP.
Li, Yonghe, Bu, Guojun, Lu, Wenyan
core   +1 more source

Epigenetic Signatures in Ovarian Cancer to Determine Potential Diagnostic/Prognostic Biomarkers

Experimed
Objective: Identification of methylation patterns in cell-free DNA (cfDNA) provides a non-invasive methodology for discovering critical biomarkers that facilitate detection and prognostic evaluation of ovarian cancer (OC).
Tuba Gunel, Maurice Jansen, Samet Topuz, Jean Helmijr, Servet Tunoğlu, Tugce Senturk Kirmizitas   +5 more
doaj   +1 more source

Slow endocytosis of the LDL receptor-related protein 1B: Implications for a novel cytoplasmic tail conformation

, 2007
The LDL receptor-related protein 1B (LRP1B) is a putative tumor suppressor homologous to LRP1. Both LRP1 and LRP1B contain cytoplasmic tails with several potential endocytosis motifs.
Li, Yonghe, Bu, Guojun, Griffith, Janice M., Schwartz, Alan L., Knisely, Jane M., Geuze, Hans J.   +5 more
core   +1 more source

The low density lipoprotein receptor-related protein 1B retains β-amyloid precursor protein at the cell surface and reduces amyloid-β peptide production

, 2004
The low density lipoprotein (LDL) receptor-related protein 1B (LRP1B) is a newly identified member of the LDL receptor family that shares high homology with the LDL receptor-related protein (LRP).
Li, Yonghe, Bu, Guojun, Hecimovic, Silva, Cam, Judy A., Knisely, Jane M., Zerbinatti, Celina V.   +5 more
core   +1 more source

LRP1b and LRP8 function in lineage commitment in the human embryo.

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of LRP1b and LRP8 as lineage commitment markers or lineage commitment cooperating factor in embryonic stem cells of the human embryo. 
openaire   +1 more source

LRP1B Gene [PDF]

, 2020
openaire   +1 more source

LRP1B wt Allele [PDF]

, 2020
openaire   +1 more source

Image_5_Association of LRP1B Mutation With Tumor Mutation Burden and Outcomes in Melanoma and Non-small Cell Lung Cancer Patients Treated With Immune Check-Point Blockades.TIFF

, 2019
Background: Tumor mutation burden (TMB) have been served as the most prevalent biomarkers to predict immunotherapy response. LRP1B (low-density lipoprotein receptor-related protein 1B) is frequently mutated in melanoma, non-small cell lung cancer (NSCLC)
Qian Wu (209382), Hao Chen (5190), Yueliang Yao (2153293), Xin Wang (91924), Min Mao (646400), Wei Chong (782416)   +5 more
core   +1 more source

Clinical Utility of Broad-Panel Profiling in Non-Small Cell Lung Cancer: Pairwise Co-Mutational Gene Patterns and PD-L1 Associations Define Stage-Specific Prognosis. [PDF]

Genes (Basel)
Sassorossi C, De Paolis E, Evangelista J, Dalfovo D, Cancellieri A, Carriero I, Campanella A, Troost EGC, Löck S, Ádány R, Farré N, Öztürk E, Trisolini R, Boldrini L, Stefani A, Urbani A, Bria E, Margaritora S, Minucci A, Lococo F.   +19 more
europepmc   +1 more source