Results 171 to 180 of about 28,054 (245)

Urinary Biomarkers in Parkinson's Disease: A Structured Integrative Review of Pathophysiological Pathways. [PDF]

Med Sci (Basel)
Santos HQP, Sumita NM, Alberto-Silva C, Echeverry MB.   +3 more
europepmc   +1 more source

Genetic Associations of Parkinson's Disease Clinical, Pathological, and Data-Driven Subtypes. [PDF]

Genes (Basel)
Negida A, Abouelmagd ME, Hamed BM, Hawas Y, Dziri A, Negida Y, Berman BD, Barrett MJ.   +7 more
europepmc   +1 more source

Role of LRRK2 in physiological activities, diseases, and therapy. [PDF]

Chin Med J (Engl)
Wang Z, Li Q, Yan L, Du M, Wei X.
europepmc   +1 more source

Inflammatory signaling differentially changes chromatin accessibility and gene expression of the PD- associated kinase LRRK2 between human and mice. [PDF]

Mol Neurodegener
Beilina A, Park JH, Landeck N, Chia R, Ding J, Reed X, Bailey H, Kim C, Kaganovich A, Acri DJ, Brooks J, Mann A, Zaghloul KA, Marsan E, Raphael Gibbs J, DeCasien A, Cookson MR.   +16 more
europepmc   +1 more source

Functional single nucleotide polymorphisms in CACNA2D3 and other autophagy-related genes are associated with leprosy among Brazilians. [PDF]

PLoS Negl Trop Dis
Espasandin I, Cardoso CC, Leal-Calvo T, Mendes MA, Latini ACP, de Castro SHM, Leturiondo AL, Bezerra OCL, Pinheiro RO, Sales AM, Moraes MO, Kehdy FSG.   +11 more
europepmc   +1 more source

Synthesis and Preclinical Evaluation of [¹¹C]GNE-0877 as a Potential PET Radioligand for Imaging Brain Leucine-Rich Repeat Kinase 2. [PDF]

ACS Omega
Jana S, Nerella SG, Samanta SS, Liow JS, Raso IM, Montero-Santamaria JA, Zoghbi SS, Wu S, Innis RB, Telu S, Pike VW, Ding YS.   +11 more
europepmc   +1 more source

Mechanistic of LRRK2-Mediated Pyroptosis Via the NLRP3/Caspase-1/GSDMD Pathway in Parkinson's Disease Progression. [PDF]

Inflammation
Li J, Zheng Z, Zhang X, Shen L, Xue C, Lu L, Xu X, Li F, Lu G.   +8 more
europepmc   +1 more source

LRRK2 kinase mediates increased GCase activity in microglia in response to IFNγ-induced proinflammatory stimulation. [PDF]

NPJ Parkinsons Dis
MacDougall EJ, Chen CX, Deneault E, You Z, Kalaydjian D, Abdian N, Durcan TM, Senkevich K, Gan-Or Z, Fon EA.   +9 more
europepmc   +1 more source

The genetic spectrum of LRRK2 variants in Parkinson's disease: findings from a large Chinese cohort. [PDF]

NPJ Parkinsons Dis
Wan J, Pan H, Chang D, Zhao Y, Xu Q, Yao L, Sun Q, Zhang X, He R, Wang C, Zhang H, Lei L, Wang Y, Li M, Wu H, Ma J, Wu Y, Xu Y, Xiong N, Wang T, Wang X, Chen L, Xu Y, Cao H, Zhang K, Liu W, Zhang Y, Mao C, Wang Q, Xue Z, Zhang Z, Cheng O, Huang W, Zhao G, Cui G, Chen T, Wang P, Di W, Liu H, Zheng H, Chen C, Guo H, Xia K, Zhang Z, Yuan K, Li J, Wang J, Guo J, Shen L, Jiang H, Liu C, Liu J, Chan P, Liu Z, Tang B, Parkinson’s Disease & Movement Disorders Multicenter Database and Collaborative Network in China (PD-MDCNC), China Essential Tremor Alliance (CETA).   +56 more
europepmc   +1 more source

Targeting leucine-rich repeat kinase 2 overcomes resistance to oncolytic herpes simplex virus-based therapies in glioblastoma. [PDF]

Nat Commun
Qin Y, Liang Z, Yu M, Lin N, Wang N, Huang X, Chen S, Peng Q, Lin Y, Wang H, Rao Y, Xu Z, Huang S, Cai J, Li Y, Zhang J, Lin C, Tan G, Xia N, Huang C.   +19 more
europepmc   +1 more source