Results 1 to 10 of about 18,393 (195)

Longer leukocyte telomere length increases the odds of premature rupture of membranes: a cross-sectional study based on UK Biobank [PDF]

Scientific Reports
This study aimed to explore the association between leukocyte telomere length (LTL) and premature rupture of membranes (PROM). This cross-sectional study included a total of 170,841 participants from the UK Biobank.
Chunting Xiao, Yan Su, Chuan Peng, Weike Li, Zhenyin Chen, Jing Long, Qianyan Shen, Yuquan Ran, Yingxiong Wang, Jinbo Hu, Rufei Gao   +10 more
doaj   +2 more sources

Leukocyte Telomere Length and Its Polygenic Risk Score in Post‐Stroke Cognitive Impairment: Evidence From a Multicenter Cohort Study [PDF]

Brain and Behavior
Background Post‐stroke cognitive impairment (PSCI) is a frequent and disabling consequence of ischemic stroke. Leukocyte telomere length (LTL), a biomarker of systemic biological aging, has been implicated in cognitive outcomes, but evidence in stroke ...
Kunying Zhao, Yanfeng Shi, Hongyi Yan, Hongyu Zhou, Jiejie Li, Si Cheng, Zhe Xu, Yuesong Pan, Zixiao Li, Xia Meng, Hao Li, Xiaoling Liao, Jing Jing, Yongjun Wang   +13 more
doaj   +2 more sources

Arginase 2 deficiency mitigates sepsis-associated acute kidney injury by alleviating lipid accumulation. [PDF]

Clin Transl Med
1. Spatiotemporal multi‐omics atlas reveals regional metabolic and proteomic specificity during sepsis‐to‐S‐AKI progression. 2. Arginine metabolism is central to S‐AKI pathogenesis, with declining arginine levels correlating with worsening renal function. 3. ARG2 upregulation in renal tubules and macrophages drives tubular lipid accumulation and kidney
Xin Y, Liu Y, Zhang N, Huang P, Zhang Q, Luo Y, Wang X, Zhang X, Wu T, Liu F, Xiao Y, Shen L, Zhang W, Wang X, Meng X, Bai Y, Wang X, Zhang N, Xu Q, Meng H, Zheng X, Cheng L, Yu K, Wang C.   +23 more
europepmc   +2 more sources

Verification of the Bully Election Algorithm for Distributed Systems Using TLA+ and PlusCal

Современные информационные технологии и IT-образование, 2022
This article is devoted to verification of the bully election algorithm for distributed systems with TLA+ and PlusCal. In this work, we show an overview of the basic information about distributed systems, then we show definition of election algorithms ...
Aleksey Polyakov, Elisey Nigodin, Elena Polupanova, Pavel Usov   +3 more
doaj   +1 more source

The causal relationship between genetically determined telomere length and meningiomas risk

Frontiers in Neurology, 2023
BackgroundStudies have shown that longer leukocyte telomere length (LTL) is significantly associated with increased risk of meningioma. However, there is limited evidence concerning the causal association of LTL with benign and malignant meningiomas or ...
Weijie Yu, Weijie Yu, Yunyun Mei, Zhenwei Lu, Zhenwei Lu, Liwei Zhou, Fang Jia, Fang Jia, Sifang Chen, Sifang Chen, Zhanxiang Wang, Zhanxiang Wang   +11 more
doaj   +1 more source

Genetic and clinical determinants of telomere length

HGG Advances, 2023
Summary: Many epidemiologic studies have identified important relationships between leukocyte telomere length (LTL) with genetics and health. Most of these studies have been significantly limited in scope by focusing predominantly on individual diseases ...
Patrick Allaire, Jing He, John Mayer, Luke Moat, Peter Gerstenberger, Reynor Wilhorn, Sierra Strutz, David S.L. Kim, Chenjie Zeng, Nancy Cox, Jerry W. Shay, Joshua Denny, Lisa Bastarache, Scott Hebbring   +13 more
doaj   +1 more source

Longitudinal telomere length and body composition in healthy term-born infants during the first two years of life.

PLoS ONE, 2021
ObjectiveLeukocyte telomere length (LTL) is one of the markers of biological aging as shortening occurs over time. Shorter LTL has been associated with adiposity and a higher risk of cardiovascular diseases.
Kirsten S de Fluiter, Veryan Codd, Matthew Denniff, Gerthe F Kerkhof, Inge A L P van Beijsterveldt, Laura M Breij, Nilesh J Samani, Marieke Abrahamse-Berkeveld, Anita C S Hokken-Koelega   +8 more
doaj   +1 more source

Sub-optimal maternal gestational gain is associated with shorter leukocyte telomere length at birth in a predominantly Latinx cohort of newborns

Maternal Health, Neonatology and Perinatology, 2023
Objective To assess in utero exposures associated with leukocyte telomere length (LTL) at birth and maternal LTL in a primarily Latinx birth cohort. Study design Mothers and newborns were recruited postnatally before 24 h of life.
Apurva Prasad, Jue Lin, Laura Jelliffe-Pawlowski, Kimberley Coleman-Phox, Larry Rand, Janet M Wojcicki   +5 more
doaj   +1 more source

TERC Variants Associated with Short Leukocyte Telomeres: Implication of Higher Early Life Leukocyte Telomere Attrition as Assessed by the Blood-and-Muscle Model

Cells, 2020
Short leukocyte telomere length (LTL) is associated with atherosclerotic cardiovascular disease (ASCVD). Mendelian randomisation studies, using single nucleotide polymorphisms (SNPs) associated with short LTL, infer a causal role of LTL in ASCVD.
Simon Toupance, Maria G. Stathopoulou, Alexandros M. Petrelis, Vesna Gorenjak, Carlos Labat, Tsung-Po Lai, Sophie Visvikis-Siest, Athanase Benetos   +7 more
doaj   +1 more source

Shorter leukocyte telomere length protects against NAFLD progression in children

Scientific Reports, 2023
Leukocyte telomere length (LTL) gets shorter with each cell division and is also sensitive to reactive oxygen species damage and inflammatory processes.
Janet M. Wojcicki, Ryan M. Gill, Laura Wilson, Jue Lin, Philip Rosenthal   +4 more
doaj   +1 more source