Results 71 to 80 of about 17,864 (198)
VirusesReporter viruses are valuable tools for studying infections at the cellular level and in living animals. They also enable rapid, high-throughput antiviral drug screening and serological studies.
Po-Ling Chen +4 more
doaj +1 more source
Viruses, 2016 Rabies is a highly fatal zoonotic disease which is primarily caused by rabies virus (RABV) although other members of the genus Lyssavirus can cause rabies as well. As yet, 14 serologically and genetically diverse lyssaviruses have been identified, mostly
Sarah Moeschler +4 more
doaj +1 more source
Substrate Cooperativity in Marine Luciferases
PLoS ONE, 2012 Marine luciferases are increasingly used as reporters to study gene regulation. These luciferases have utility in bioluminescent assay development, although little has been reported on their catalytic properties in response to substrate concentration.
George Tzertzinis +2 more
openaire +4 more sources
An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light
Advanced Functional Materials, EarlyView.NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee +4 more
wiley +1 more source
A cost-effective dual reporter system in Nicotiana benthamiana
Frontiers in Plant ScienceDual reporter assay has been widely used for quantification of gene expression in various model systems. However, the assay is dependent on commercial kits, which may be inhibitory for many low-budget academic laboratories or high throughput screening ...
Zeru Zhang +11 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold +9 more
wiley +1 more source
From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function
Advanced Healthcare Materials, EarlyView.The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini +2 more
wiley +1 more source
Regulation of WDFY1 Expression by miRNAs, Transcription Factors, and IL-6 in Murine Mesangial Cells
CellsWD40 repeat and FYVE containing protein 1 (WDFY1) functions in membrane trafficking and protein complex scaffolding. WDFY1 has been studied in the immune system and in different oncogenic conditions.
David E. Adams +6 more
doaj +1 more source
Advanced Materials, EarlyView.An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang +5 more
wiley +1 more source
Visualization of Leishmania tropica Infection in BALB/c Mice by Bioluminescence Imaging
Iranian Biomedical Journal, 2020 Background: Leishmania tropica is the cause of more than one form of leishmaniasis and lacks a known reservoir animal. This study compares the potential infectivity of recombinant and wild-type L. tropica in BALB/c mice.
Mahdieh Eskandar +6 more
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