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Lumacaftor/Ivacaftor: A Review in Cystic Fibrosis
Drugs, 2016Lumacaftor/ivacaftor (Orkambi™) is a fixed-dose tablet containing a corrector (lumacaftor) and potentiator (ivacaftor) of the cystic fibrosis transmembrane conductance regulator (CFTR) and is the first therapy approved to treat the underlying cause of cystic fibrosis in patients (aged ≥12 years) homozygous for the most common CFTR mutation, F508del ...
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Brivaracetam, lumacaftor/ivacaftor, and deoxycholic acid
Journal of the American Pharmacists Association, 2016Daniel A, Hussar, Jerry Rachel, George
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