Results 31 to 40 of about 504,468 (237)

Changes in intervertebral disc morphology persist 5 mo after 21-day bed rest [PDF]

, 2011
As part of the nutrition- countermeasures (NUC) study in Cologne, Germany in 2010, seven healthy male subjects underwent 21 days of head-down tilt bed rest and returned 153 days later to undergo a second bout of 21-day bed rest. As part of this model,
Daniel L. Belavý, Petra Frings-Meuthen, Jochen Zange, Heer, Martina, Rittweger, Jörn, Böhme, Gisela, Martina Heer, Frings-Meuthen, Petra, Gisela Böhme, Jörn Rittweger, Zange, Jochen, Bansmann, Martin, P. Martin Bansmann, Felsenberg, Dieter, Dieter Felsenberg, Belavy, Daniel Ludovic   +15 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Study and analysis of the correlation between lumbar spondylolisthesis and Modic changes

Frontiers in Surgery
BackgroundThis study aimed to explore the risk factors of Modic changes in lumbar spondylolisthesis.MethodsThe distribution of Modic changes in different types of lumbar spondylolisthesis, degree of spondylolisthesis, and degree of intervertebral disc ...
Guang-qing Li, Xiao Kang, Wei Li, Shi-shen Pei   +3 more
doaj   +1 more source

Variants of ACAN are associated with severity of lumbar disc herniation in patients with chronic low back pain. [PDF]

PLoS ONE, 2017
Disc herniation is a complex spinal disorder associated with disability and high healthcare cost. Lumbar disc herniation is strongly associated with disc degeneration.
Romain Shanil Perera, Poruwalage Harsha Dissanayake, Upul Senarath, Lalith Sirimevan Wijayaratne, Aranjan Lional Karunanayake, Vajira Harshadeva Weerabaddana Dissanayake   +5 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Implication of microglia activation and CSF1/CSF1R pathway in lumbar disc degeneration-related back pain

Molecular Pain, 2018
Back pain is common and costly. Although lumbar disc degeneration has long been regarded as a major contributor to back pain, how disc degeneration leads to back pain remains unclear.
Ge Yang, Lunhao Chen, Zhihua Gao, Yue Wang   +3 more
doaj   +1 more source

Correlation between multifidus fatty atrophy and lumbar disc degeneration in low back pain

BMC Musculoskeletal Disorders, 2019
Background Chronic low back pain (LBP) is common and associated with lumbar disc herniation. The purpose of this study was to investigate if the grade of lumbar disc degeneration correlates with the degree of lumbar multifidus muscle (LMM) fatty atrophy.
Cosmin Faur, Jenel M. Patrascu, Horia Haragus, Bogdan Anglitoiu   +3 more
doaj   +1 more source

Analysis of the Relationship between Hypertrophy of the Ligamentum Flavum and Lumbar Segmental Motion with Aging Process [PDF]

Asian Spine Journal, 2016
Study DesignRetrospective cross-sectional study.PurposeTo investigate the relationship between ligamentum flavum (LF) hypertrophy and lumbar segmental motion.Overview of LiteratureThe pathogenesis of LF thickening is unclear and whether the thickening ...
Toyomi Yoshiiwa, Masashi Miyazaki, Masanori Kawano, Shinichi Ikeda, Hiroshi Tsumura   +4 more
doaj   +1 more source

Radiological Study of Lumbar Disc Degeneration and its Clinical Significance

GAIMS Journal of Medical Sciences, 2023
Introduction: Intervertebral disc is a complex structure consisting of highly specialized connective tissue, a combination of hyaline cartilage, fibrocartilage, mucopolysaccharide & dense collagen fibers.
Mrinalini Gaikwad, Sachin Patil, Dixit Chauhan, Himanshu Joshi   +3 more
doaj   +1 more source