New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites:an open resource [PDF]
, 2015 Using whole-cell phenotypic assays, the GlaxoSmithKline high-throughput screening (HTS) diversity set of 1.8 million compounds was screened against the three kinetoplastids most relevant to human disease, i.e.
Alonso-Padilla, Julio +20 more
core +2 more sources
New properties of a bioinspired pyridine benzimidazole compound as a novel differential staining agent for endoplasmic reticulum and Golgi apparatus in fluorescence live cell imaging [PDF]
, 2018 Indexación: Scopus.In this study, we explored new properties of the bioinspired pyridine benzimidazole compound B2 (2,4-di-tert-butyl-6-(3H-imidazo[4,5-c]pyridine-2-yl)phenol) regarding its potential use as a differential biomarker.
Alexander Carreño +10 more
core +8 more sources
Biocompatible NaYF4:Yb,Er upconversion nanoparticles: Colloidal stability and optical properties
Journal of Saudi Chemical Society, 2021 Currently, highly luminescent colloidal upconversion nanoparticles (UCNPs) have expanded an increasing interest of researchers because of their facilitating lability in the biomedical/clinical field.
Anees A. Ansari +2 more
doaj
Química Nova, 2005 The history of the rare earths is rich in innovation and these elements have been the object of study of a number of scientists. Rare earths are used practically in almost all aspects of life and these applications are due to their outstanding properties,
Tereza S. Martins, Paulo Celso Isolani
doaj +1 more source
Development of novel orthogonal genetic circuits, based on extracytoplasmic function (ECF) σ factors [PDF]
, 2019 The synthetic biology field aims to apply the engineering 'design-build-test-learn' cycle for the implementation of synthetic genetic circuits modifying the behavior of biological systems. In order to reach this goal, synthetic biology projects use a set
Vecchione, Stefano
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Engineered ferritin for lanthanide binding [PDF]
, 2018 Ferritin H-homopolymers have been extensively used as nanocarriers for diverse applications in the targeted delivery of drugs and imaging agents, due to their unique ability to bind the transferrin receptor (CD71), highly overexpressed in most tumor ...
Baiocco, Paola +13 more
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Rare earth based nanostructured materials: Synthesis, functionalization, properties and bioimaging and biosensing applications [PDF]
, 2017 Rare earth based nanostructures constitute a type of functional materials widely used and studied in the recent literature. The purpose of this review is to provide a general and comprehensive overview of the current state of the art, with special focus ...
Becerro Nieto, Ana Isabel +7 more
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Micro-modulated luminescence tomography [PDF]
, 2013 Imaging depth of optical microscopy has been fundamentally limited to millimeter or sub-millimeter due to light scattering. X-ray microscopy can resolve spatial details of few microns deeply inside a sample but the contrast resolution is still inadequate to depict heterogeneous features at cellular or sub-cellular levels.
arxiv +1 more source
Super-Resolution Imaging With Lanthanide Luminescent Nanocrystals: Progress and Prospect
Frontiers in Bioengineering and Biotechnology, 2021 Stimulated emission depletion (STED) nanoscopy has overcome a serious diffraction barrier on the optical resolution and facilitated new discoveries on detailed nanostructures in cell biology.
Hongxin Zhang +3 more
doaj +1 more source
, 2016 Vibrio harveyi, a luminescent Gram-negative motile marine bacterium, is an important pathogen responsible for causing severe diseases in shrimp, finfish and molluscs leading to severe economic losses.
Baruah, Sri Kartik +3 more
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