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Adenocarcinoma of the lung [PDF]
Thorax, 1969 The clinical and histological features of 53 cases of adenocarcinoma of the lung are presented. In more than one-third of the patients the tumour was a solitary nodule, raising the possibility that it might be a metastatic focus. Although histological features may suggest an origin from such sources as the kidney, uterus, ovary or bowel, nearly all ...
J. R. Hinds, G. C. Hitchcock
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Immune Resistance in Lung Adenocarcinoma [PDF]
Cancers, 2021 Lung cancer is the leading cancer killer worldwide, imposing grievous challenges for patients and clinicians. The incidence of lung adenocarcinoma (LUAD), the main histologic subtype of lung cancer, is still increasing in current-, ex-, and even non-smokers, whereas its five-year survival rate is approximately 15% as the vast majority of patients ...
Magda Spella, Georgios T. Stathopoulos
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Lung adenocarcinoma promotion by air pollutants
Nature, 2023 A complete understanding of how exposure to environmental substances promotes cancer formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-step process: an initiating step that induces mutations in healthy cells, followed by a promoter step that triggers cancer development1.
William Hill +211 more
openaire +8 more sources
KLF5 facilitates lung adenocarcinoma metastasis by regulating the epithelial-mesenchymal transition pathway through RHPN2 [PDF]
Journal of Translational MedicineBackground Distant metastasis is a primary factor contributing to the significantly shorter survival time of patients with advanced lung adenocarcinoma.
Tao Zhang +11 more
doaj +2 more sources
Hepatoid Adenocarcinoma of the Lung [PDF]
Technology in Cancer Research & Treatment, 2021 Hepatoid adenocarcinoma of the lung (HAL) is an comparatively rare malignant tumor originating from the lung with shorter survival. HAL morphologically and pathologically exhibits hepatocellular carcinoma (HCC)-like characteristics, while its clinical features resemble pulmonary adenocarcinoma.
Meihui Li, Ying Fan, Hongyang Lu
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Acta Biochimica et Biophysica Sinica, 2023 The clinical oncogenic functions and mechanisms of activating transcription factor 1 (ATF1) in the progression of lung adenocarcinoma have not been completely elucidated.
Mei Jinhong +8 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundThe main aim of the study was to determine the risk factors of lung adenocarcinoma and to analyze the variations in the incidence of lung adenocarcinoma according to time, sex, and smoking status in North China.MethodsPatients with lung cancer ...
Daojuan Li +5 more
doaj +1 more source
Biomedicines, 2023 Objective: The RNA-binding protein RBM10 can regulate apoptosis during the proliferation and migration of pancreatic cancer, endometrial cancer, and osteosarcoma cells; however, the molecular mechanism underlying lung adenocarcinoma is rarely reported ...
Liusheng Wu +7 more
semanticscholar +1 more source
High GNG4 expression is associated with poor prognosis in patients with lung adenocarcinoma
Thoracic Cancer, 2022 Background The purpose of this study was to explore the reason for guanine nucleotide binding‐protein gamma subunit‐4 (GNG4) overexpression and the relationship between GNG4 overexpression and the poor prognosis of lung adenocarcinoma (LUAD) patients ...
Bodong Zhou +7 more
doaj +1 more source
Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma
Cancer Communications, 2022 Resistance to ferroptosis, a regulated cell death caused by iron‐dependent excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma (LUAD).
Xiao Zhang +18 more
semanticscholar +1 more source