Results 11 to 20 of about 2,211,257 (305)

Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival [PDF]

, 2017
LDL receptor-related proteins (LRPs) are transmembrane receptors involved in endocytosis, cell-signaling, and trafficking of other cellular proteins. Considerable work has focused on LRPs in the fields of vascular biology and neurobiology.
Gilder, Andrew S., Gonias, Steven L., Karimi-Mostowfi, Nicki, Mantuano, Elisabetta, Murray, Sarah S.   +4 more
core   +10 more sources

Expression of MAD2L1 in Lung Adenocarcinoma and Its Effect on Immune Microenvironment

Zhongliu Fangzhi Yanjiu, 2022
Objective To investigate the expression of MAD2L1 in lung adenocarcinoma and its effect on the prognosis and immune microenvironment of patients. Methods The difference of MAD2L1 expression in lung adenocarcinoma tissue and normal lung tissue was ...
LIU Yingbo, LIU Xiaohong, RU Meihua, LI Jianqiang   +3 more
doaj   +1 more source

Lung Adenocarcinoma Tumor Origin: A Guide for Personalized Medicine

Cancers, 2022
Simple Summary Lung cancer is the leading cause of cancer-related death worldwide, with an average 5-year survival rate of approximately 15%. Among the multiple histological type of lung cancer, adenocarcinoma is the most common.
L. Seguin, Manon Durandy, C. Féral
semanticscholar   +1 more source

Immunomodulatory Factor TIM3 of Cytolytic Active Genes Affected the Survival and Prognosis of Lung Adenocarcinoma Patients by Multi-Omics Analysis

Biomedicines, 2022
[Objective] Using multi-omics research methods to explore cytolytic activity-related genes through the immunoregulatory factors HAVCR2 (TIM3) affecting the survival and prognosis of lung adenocarcinoma.
Liusheng Wu, Yanfeng Zhong, Dingwang Wu, Pengcheng Xu, X-J Ruan, Jun Yan, Jixian Liu, Xiaoqiang Li   +7 more
semanticscholar   +1 more source

UCHL1 acts as a potential oncogene and affects sensitivity of common anti-tumor drugs in lung adenocarcinoma

World Journal of Surgical Oncology, 2022
Background Lung adenocarcinoma is the leading cause of cancer death worldwide. Recently, ubiquitin C-terminal hydrolase L1 (UCHL1) has been demonstrated to be highly expressed in many tumors and plays the role of an oncogene.
Jianbo Yao, Abdusemer Reyimu, Ao Sun, Zaxi Duoji, Wubi Zhou, Song Liang, Suxia Hu, Xiang Wang, Jingjing Dai, Xiaoguang Xu   +9 more
doaj   +1 more source

ARNTL2 is an indicator of poor prognosis, promotes epithelial-to-mesenchymal transition and inhibits ferroptosis in lung adenocarcinoma

Translational Oncology, 2022
Objectives: ARNTL2, as a circadian transcription factor, has been recently proposed to play an important role in a variety of tumors. however, the role of ARNTL2 in lung carcinogenesis and progression remains unclear.
Huan Zhang, Guangyao Shan, Xing Jin, Xiangyang Yu, GuoShu Bi, Mingxiang Feng, Hao Wang, Miao Lin, Cheng Zhan, Qun Wang, Ming Li   +10 more
doaj   +1 more source

Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma. [PDF]

, 2015
Mice in which lung epithelial cells can be induced to express an oncogenic Kras(G12D) develop lung adenocarcinomas in a manner analogous to humans. A myriad of genetic changes accompany lung adenocarcinomas, many of which are poorly understood.
Caswell, DR, Chu, K, Chuang, C-H, Kay, MA, Kim, HK, Roy-Chaudhuri, B, Sayles, LC, Sweet-Cordero, EA, Valdmanis, PN, Winslow, MM, Zhang, Y, Zheng, Y   +11 more
core   +5 more sources

Veillonella parvula promotes the proliferation of lung adenocarcinoma through the nucleotide oligomerization domain 2/cellular communication network factor 4/nuclear factor kappa B pathway

Discover Oncology, 2023
Enrichment of Veillonella parvula in the lung microbiota is strongly associated with non-small cell lung cancer (NSCLC) and induces the progression of lung adenocarcinoma in vivo, but its actual role and mechanism remain unexplored.
Wen Zeng, Yuhuan Wang, Zhe Wang, Mengge Yu, Kang Liu, Chengzhu Zhao, Yiyun Pan, Shudong Ma   +7 more
doaj   +1 more source

miR-625-5p promotes proliferation and invasion of lung adenocarcinoma by targeting PRKACA [PDF]

Zhongguo aizheng zazhi, 2021
Background and purpose: Lung adenocarcinoma is a subtype of non-small cell lung cancer. Although much progress has been made in the diagnosis and treatment of lung adenocarcinoma, the clinical prognosis and overall survival of advanced lung  ...
HU Yaqiong , BAI Jun , CHEN Lin , CHEN Xinlu , ZHANG Liping , ZHOU Dandan , WANG Yu , YIN Chonggao , LI Hongli , LIU Yuqing
doaj   +1 more source

Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma

Nature Communications, 2020
Advanced metastatic cancer poses utmost clinical challenges and may present molecular and cellular features distinct from an early-stage cancer. Herein, we present single-cell transcriptome profiling of metastatic lung adenocarcinoma, the most prevalent ...
N. Kim, H. Kim, K. Lee, Yourae Hong, J. Cho, J. Choi, Jung-Il Lee, Y. Suh, B. Ku, Hye Hyeon Eum, Soyean Choi, Yoon-La Choi, Je-Gun Joung, W. Park, H. Jung, Jong-Mu Sun, Se-Hoon Lee, J. Ahn, Keunchil Park, M. Ahn, Hae-Ock Lee   +20 more
semanticscholar   +1 more source