Results 21 to 30 of about 273,871 (338)

GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma

BMC Cancer, 2018
Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei, Kun Zhang, Haifeng Qin, Jinlong Zhu, Qiaoxi Qin, Yang Yu, Hong Wang   +6 more
doaj   +1 more source

MEK5 promotes lung adenocarcinoma [PDF]

European Respiratory Journal, 2018
MEK5 acts as an oncogenic driver in mice lung cancer and is pivotal for human lung adenocarcinoma http://ow.ly ...
Sánchez Fernández, Adrián, Ortíz Ruíz, María Jesús, Re-Louhau, María Florencia, Ramos, Isabel, Blanco-Múñez, Óscar, Ludeña de la Cruz, María Dolores, Abad Hernández, María Mar, Sánchez Martín, Manuel Adolfo, Pandiella Alonso, Atanasio, Esparís Ogando, Azucena   +9 more
openaire   +4 more sources

Feasibility of radical cardiac‐sparing, treatment planning strategies for patients with locally advanced, non‐small cell lung cancer

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose A set of treatment planning strategies were designed and retrospectively implemented for locally advanced, non‐small cell lung cancer (NSCLC) patients in order to minimize cardiac dose without compromising target coverage goals. Methods Retrospective analysis was performed for 20 NSCLC patients prescribed to 60–66 Gy that received a ...
Joshua P. Kim, Jake Dewalt, Aharon Feldman, Khaled Adil, Benjamin Movsas, Indrin J. Chetty   +5 more
wiley   +1 more source

Hepatoid adenocarcinoma of the lung

Autopsy and Case Reports, 2013
Lung adenocarcinomas with a mixture of tubular or papillary pattern, sheet-like or trabecular architecture, eosinophilic cytoplasm with centrally located nuclei and alpha-fetoprotein-producing cells have been described as hepatoid adenocarcinomas.
João Augusto dos Santos Martines, Fernando Peixoto Ferraz de Campos, Lívia Barreira Cavalcante, Aloísio Felipe-Silva   +3 more
openaire   +3 more sources

Progesterone/Org inhibits lung adenocarcinoma cell growth via membrane progesterone receptor alpha

Thoracic Cancer, 2020
Background The aim of this study was to determine whether progesterone could inhibit the growth of lung adenocarcinoma cells via membrane progesterone receptor alpha (mPRα) and elucidate its potential mechanism.
Jian Xiao, Xi Chen, Xiaoxiao Lu, Mingxuan Xie, Bixiu He, Shuya He, Shaojin You, Qiong Chen   +7 more
doaj   +1 more source

Long noncoding RNA expression profiles of lung adenocarcinoma ascertained by microarray analysis. [PDF]

PLoS ONE, 2014
BACKGROUND:Long noncoding RNAs (lncRNAs) have been shown to be involved in the development and progression of lung cancer. However, the roles of lncRNAs in lung cancer are not well understood.
Gang Xu, Jie Chen, Qinshi Pan, Keta Huang, Jingye Pan, Wenhui Zhang, Jian Chen, Fangyou Yu, Tieli Zhou, Yumin Wang   +9 more
doaj   +1 more source

XXYLT1 methylation contributes to the occurrence of lung adenocarcinoma

Medicine, 2021
Abstract Background: There is evidence that DNA methylation play major roles in lung cancer. In our previously study, C3 or f21 , also referred to as XXYLT1, rs2131877 polymorphism is associated with a reduced risk of lung adenocarcinoma. So, we explored the role of XXYLT1 methylation in lung adenocarcinoma.
Zeng, Hui, Wang, Ying, Wang, Ying, Zhang, Yongjun   +3 more
openaire   +3 more sources

DEPDC1 is Highly Expressed in Lung Adenocarcinoma and Promotes Tumor Cell Proliferation

Chinese Journal of Lung Cancer, 2021
Background and objective Lung cancer is the leading cause of death worldwide, and lung adenocarcinoma is the main subtype of lung cancer. DEP domain-containing 1 (DEPDC1) has been proved to be closely related to the occurrence and development of most ...
Jian SHEN, Mengmeng XI
doaj   +1 more source

Overexpression of RhoV Promotes the Progression and EGFR-TKI Resistance of Lung Adenocarcinoma

Frontiers in Oncology, 2021
BackgroundThe Rho GTPase family with ~20 member genes play central roles in a wide variety of cellular processes and tumor cell migration and metastasis.
Hongjin Chen, Ruixue Xia, Long Jiang, Yong Zhou, Haojun Xu, Weiwei Peng, Chengyun Yao, Guoren Zhou, Yijie Zhang, Hongping Xia, Hongping Xia, Hongping Xia, Yongsheng Wang   +12 more
doaj   +1 more source

H&E-based Computational Biomarker Enables Universal EGFR Screening for Lung Adenocarcinoma [PDF]

arXiv, 2022
Lung cancer is the leading cause of cancer death worldwide, with lung adenocarcinoma being the most prevalent form of lung cancer. EGFR positive lung adenocarcinomas have been shown to have high response rates to TKI therapy, underlying the essential nature of molecular testing for lung cancers.
arxiv