Results 11 to 20 of about 418,602 (269)

Research Progress of Epigenetics in Pathogenesis and Treatment of Malignant Tumors

open access: yesChinese Journal of Lung Cancer, 2020
Epigenetic modification is closely related to the occurrence and development of tumors. It mainly regulates gene function and expression level through DNA methylation, histone modification, regulation of non-coding RNA and chromatin structure ...
Pan WANG   +10 more
doaj   +1 more source

MiR-192 Confers Cisplatin Resistance by Targeting Bim in Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2014
Background and objective Cisplatin is the first-line drug for the chemotherapy of non-small cell lung cancer (NSCLC), but the acquired chemoresistance restricted the effect of its treatment.
Fang ZHANG   +13 more
doaj   +1 more source

MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancer

open access: yesBMC Cancer, 2021
Background MicroRNAs (miRNAs) have been reported to play significant roles in non-small-cell lung cancer (NSCLC). However, the roles of microRNA (miR)-1915-3p in NSCLC remain unclear.
Hongli Pan   +13 more
doaj   +1 more source

Pancreatic metastasis from lung adenocarcinoma

open access: yesJournal of General and Family Medicine, 2023
TTF-1 is a highly useful marker to assist in differentiating between pulmonary and nonpulmonary, nonthyroid adenocarcinomas. Our case shows that TTF-1 is highly useful in differentiating between pancreatic metastasis from lung adenocarcinoma and primary pancreatic cancer, especially when the clinical course and imaging findings are not helpful for ...
Naoki Aoyama   +3 more
openaire   +3 more sources

Nicotine Induced Lung Cancer Cells Epithelial-mesenchymal Transition 
and Promote Its Vitro Invasion Potential

open access: yesChinese Journal of Lung Cancer, 2016
Background and objective Our previous study found that nicotine could induce lung cancer cell epithelial-mesenchymal transition (EMT). The aim of this study is to explore the relationship between nicotine-induced EMT and lung cancer invasion and ...
Yanxu HOU   +10 more
doaj   +1 more source

EML4-ALK-mediated activation of the JAK2-STAT pathway is critical for non-small cell lung cancer transformation

open access: yesBMC Pulmonary Medicine, 2021
Background The echinoderm microtubule-associated protein-like-4 anaplastic lymphoma kinase (EML4-ALK) fusion gene was identified in a subset of non-small cell lung cancer (NSCLC) patients. They responded positively to ALK inhibitors.
Ying Li   +6 more
doaj   +1 more source

Primary chondroma of posterior mediastinum with Horner’s syndrome: a case report

open access: yesWorld Journal of Surgical Oncology, 2018
Background Chondroma is a slowly growing, benign cartilaginous tumor which predominantly occurs in long bones of the hands and feet. Primary mediastinal chondroma is rare, especially with Horner’s syndrome.
Xiaoqian Xu   +5 more
doaj   +1 more source

Identification of a novel oxidative stress-related prognostic model in lung adenocarcinoma

open access: yesFrontiers in Pharmacology, 2022
Background: Oxidative stress (OxS) participates in a variety of biological processes, and is considered to be related to the occurrence and progression of many tumors; however, the potential diagnostic value of OxS in lung cancer remains unclear.Methods:
Yifan Zhu   +15 more
doaj   +1 more source

Primary Endobronchial Plasmacytoma Involving Local Lymph Nodes and Presenting with Rare Immunoglobulin G Lambda Monoclonal Gammopathy

open access: yesCanadian Respiratory Journal, 2012
Extramedullary plasmacytoma occurring as a primary pulmonary lesion is rare. The present report describes a 42-year-old Chinese man diagnosed with primary pulmonary plasmacytoma following left lower lobectomy.
Sen Wei   +7 more
doaj   +1 more source

A retrospective stenting study on superior vena cava syndrome caused by lung cancer

open access: yesThoracic Cancer, 2020
Background Superior vena cava syndrome (SVCS) is a common condition predominantly caused by lung cancer. The presence of symptoms of SVCS, such as elevated intracranial pressure and laryngeal edema, indicates an unfavorable prognosis for lung cancer ...
Sen Wei   +8 more
doaj   +1 more source

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