Results 1 to 10 of about 431,005 (268)
MicroRNA in Lung Cancer Metastasis [PDF]
Cancers, 2019 Tumor metastasis is a hallmark of cancer, with distant metastasis frequently developing in lung cancer, even at initial diagnosis, resulting in poor prognosis and high mortality. However, available biomarkers cannot reliably predict cancer spreading sites.
Shang-Gin Wu +2 more
exaly +3 more sources
Leiomyosarcoma: Lung Metastasis
Cureus, 2023 Uterine leiomyosarcoma distant metastasis is common, and lung metastasis has been reported. However, unique cases have been identified either with late onset of metastatic disease or with large size of lung metastasis. A typical approach to avoid metastasis would be a hysterectomy. Nonetheless, metastatic recurrence is common.
Makhoul, Karim +4 more
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Cell Death and Disease, 2023 Metastasis remains major cause of treatment failure in non-small cell lung cancer (NSCLC). A comprehensive characterization of the transcriptomic landscape of NSCLC-cells with organ-specific metastatic potentials would advance our understanding of NSCLC ...
Lingling Zu +5 more
doaj +1 more source
Cell Death and Disease, 2021 Tumor progression requires the communication between tumor cells and tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) are major components of stromal cells.
Yinghui Ren +11 more
doaj +1 more source
Selectins as Mediators of Lung Metastasis [PDF]
Cancer Microenvironment, 2010 Lung metastasis remains the major cause of cancer related mortality in patients with breast, gastrointestinal, sarcoma, melanoma and kidney cancer. Here we characterize the expression of selectins during metastatic lung colonization and analyzed their function in the formation of pulmonary metastasis. E-selectin, together with VCAM-1, were detected 6 h
Läubli, H, Borsig, L
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Lung Cancer Stem-like Cells and Drug Resistance
Chinese Journal of Lung Cancer, 2022 Lung cancer remains the leading cause of cancer-related death world-wide. Therapy resistance and relapse are considered major reasons contributing to the poor survival rates of lung cancer.
Zhenhua PAN, Hongyu LIU, Jun CHEN
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MiR‐192/NKRF axis confers lung cancer cell chemoresistance to cisplatin via the NF‐κB pathway
Thoracic Cancer, 2022 Background Chemoresistance influences the therapeutic effect of cisplatin and remains a major obstacle to its clinical use. MicroRNAs are associated with drug resistance of various tumors.
Yang Li +8 more
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Breast metastasis of a lung carcinoma
BJR|case reports, 2022 Breast metastasis is a rare phenomenon (0.2–1.3%) 1 compared to primary breast lesions. Several neoplasms have been reported to metastasize to the breast such as melanoma, lymphoma and lung cancer. In this article, we report a case of breast metastasis of lung cancer confirmed by biopsy and immunohistochemistry with CT and ultrasound imaging.
Khoury, Ralph +3 more
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Research Progress of Epigenetics in Pathogenesis and Treatment of Malignant Tumors
Chinese Journal of Lung Cancer, 2020 Epigenetic modification is closely related to the occurrence and development of tumors. It mainly regulates gene function and expression level through DNA methylation, histone modification, regulation of non-coding RNA and chromatin structure ...
Pan WANG +10 more
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Thoracic Cancer, 2021 Background Lung cancer, mainly non‐small cell lung cancer (NSCLC), is one of the leading causes of death worldwide. Currently, chemotherapy is still the most significant treatment strategy for NSCLC.
Jinghao Liu +11 more
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