Results 31 to 40 of about 613,665 (308)
Frontiers in Cell and Developmental Biology, 2021 Cancer-associated fibroblasts (CAFs) are major component of tumor microenvironment (TME), which plays crucial roles in tumor growth, invasion and metastasis; however, the underling mechanism is not fully elucidated.
Xueru Guo +9 more
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MicroRNAs in non-small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential. [PDF]
, 2019 Lung cancer remains the most lethal cancer among men and women in the United States and worldwide. The majority of lung cancer cases are classified as non-small cell lung cancer (NSCLC). Developing new therapeutics on the basis of better understanding of
Petrek, Hannah, Yu, Ai-Ming
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Research Advances of m6A RNA Methylation in Non-small Cell Lung Cancer
Chinese Journal of Lung Cancer, 2020 N6-methyladenosine is one of the most prevalent mRNA modification in eukaryotes. The regulation of this pervasive mark is a dynamic and reversible process.
Hongli PAN +4 more
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Thoracic Cancer, 2021 Background: Acquired resistance of chemotherapy, especially cisplatin, is a major challenge in lung cancer treatment. We conducted this study to examine whether a cyclin D kinase 4/6 (CDK4/6) inhibitor, PD 0332991, could reverse cisplatin resistance in ...
Minghui Liu +8 more
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Endotracheal Metastasis Causing Airway Obstruction [PDF]
, 2020 Endotracheal metastasis, a critical complication of primary lung cancer, is an extremely rare lesion. A 73-year-old woman who had previously received treatment for lung cancer presented to our emergency department with dyspnea.
Fujiwara, Takashi +2 more
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Evaluating Modelling Approaches for Medical Image Annotations [PDF]
, 2010 Information system designers face many challenges with regards to selecting appropriate semantic technologies and deciding on a modeling approach for their system.
Bijan Parsia +2 more
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BACH1 Orchestrates Lung Cancer Metastasis [PDF]
Cell, 2019 Two studies in this issue position the stabilization of the transcription factor BACH1 as a critical node in the metastasis of lung cancer and propose two new therapeutic approaches for this leading cause of cancer-related deaths (Lignitto et al., 2019; Wiel et al., 2019).
Nicole M, Anderson, M Celeste, Simon
openaire +3 more sources
Cancer Medicine, 2019 Squamous cell carcinoma (SCC) is a unique clinical and histological category that accounts for about 30% of total lung cancer. To identify risk factors for lymph node metastasis and analyze the molecular features of these metastases in lung SCC, a ...
Ming Dong +9 more
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Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid metabolism act inversely on tumor progression. [PDF]
, 2020 The Western diet contains a high ratio of omega-6 (ω6) to omega-3 (ω3) polyunsaturated fatty acids (PUFA). The prototypical aryl hydrocarbon receptor (AHR) ligand, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), induces CYP1 family enzymes, which can ...
Hammock, Bruce D +5 more
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Clinical Significance and Next-Generation Sequencing of Chinese Pulmonary Sarcomatoid Carcinoma
Scientific Reports, 2017 Pulmonary Sarcomatoid Carcinoma (PSC) constitutes a heterogeneous group of non-small-cell lung carcinomas (NSCLCs) with a poor prognosis. In this study, a group of 7 patients with PSC was studied. Microscope analysis of all 7 cases revealed a pleomorphic
Xin Li +7 more
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