Results 31 to 40 of about 444,704 (269)

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Cancer-associated fibroblasts promote osimertinib resistance in non-small cell lung cancer cells via METTL1-mediated NET1 m7G modification

Cell Death and Disease
Osimertinib resistance remains a major challenge in the treatment of non-small cell lung cancer (NSCLC). Cancer-associated fibroblasts (CAFs) are the most abundant stromal cells in tumor microenvironment (TME), however, its role in osimertinib resistance
Yongmei Qian, Zhiyuan Gong, Yidan Jia, Qicheng Zhang, Limin Cao, Bingbing Li, Jiayi Zhang, Min Wang, Xiang Wu, Ke Xu   +9 more
doaj   +1 more source

A Highly Efficient In Vitro Site-directed Mutagenesis Protocol for Introducing 
Multiple-site Mutations into Target Genes

Chinese Journal of Lung Cancer, 2014
Background and objective The methods for introducing point mutations into target genes are important for dissecting the relationship of gene structure and function. Up to date, there are numbers of protocols available for the purpose.
Fanrong MENG, Chen CHEN, Yongwen LI, Haisu WAN, Qinghua ZHOU   +4 more
doaj   +1 more source

Systematic pan-cancer analysis showed that RAD51AP1 was associated with immune microenvironment, tumor stemness, and prognosis

Frontiers in Genetics, 2022
Although RAD51 associated protein 1 (RAD51AP1) is crucial in genome stability maintenance, it also promotes cancer development with an unclear mechanism.
Renwang Liu, Renwang Liu, Guangsheng Zhu, Guangsheng Zhu, Mingbiao Li, Peijun Cao, Peijun Cao, Xuanguang Li, Xuanguang Li, Xiuwen Zhang, Xiuwen Zhang, Hua Huang, Hua Huang, Zuoqing Song, Zuoqing Song, Jun Chen, Jun Chen   +16 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Construction and Expression of nm23-H1 Gene with Different Enzyme Activities and Resistant Specific shRNA in Eukaryotic Expression Vector

Chinese Journal of Lung Cancer, 2014
Background and objective It has been proven that nm23-H1 gene was a tumor metastatic suppressor gene. However, it’s molecular mechanism of suppressing metastasis remains unexplored.
Zhansheng LU, Lili GUO, Lin LI, Zhihao WU, Qinghua ZHOU   +4 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Comprehensive analyses of one-carbon metabolism related genes and their association with prognosis, tumor microenvironment, chemotherapy resistance and immunotherapy in lung adenocarcinoma

Frontiers in Molecular Biosciences, 2022
Background: Lung adenocarcinoma (LUAD) is the most common type of lung cancer and is a global public health concern. One-carbon (1C) metabolism plays a crucial role in the occurrence and development of multiple cancer types.
Ning Zhou, Ning Zhou, Quanying Tang, Quanying Tang, Haochuan Yu, Haochuan Yu, Tong Li, Tong Li, Fan Ren, Fan Ren, Lingling Zu, Lingling Zu, Gang Chen, Gang Chen, Jun Chen, Jun Chen, Song Xu, Song Xu   +17 more
doaj   +1 more source

Skin metastasis of lung carcinoma

Pan African Medical Journal, 2015
No Abstract.
Krich Sanaa, Mernissi Fatima Zahra
openaire   +4 more sources