Results 51 to 60 of about 613,665 (308)

Metastatic Uterine Leiomyosarcoma in the Upper Buccal Gingiva Misdiagnosed as an Epulis [PDF]

, 2014
Uterine leiomyosarcoma (LMS) is a rare tumor constituting 1% of all uterine malignancies. This sarcoma demonstrates an aggressive growth pattern with an high rate of recurrence with hematologic dissemination; the most common sites are lung, liver, and ...
Alesini F, Bartoli D, Battisti A, Bosco S, Cassoni A, Conte D, Lembo A, Pagnoni M, Terenzi V, Valentini V, Zadeh OR   +10 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Characteristics of the immune microenvironment and their clinical significance in non-small cell lung cancer patients with ALK-rearranged mutation

Frontiers in Immunology, 2022
BackgroundAlthough immune checkpoint inhibitors (ICIs) are one of the most important treatments for advanced-stage non-small-cell lung cancer (NSCLC), NSCLC patients with ALK-rearranged usually don’t obtain a clinical benefit.
Bo Zhang, Bo Zhang, Jingtong Zeng, Jingtong Zeng, Hao Zhang, Hao Zhang, Shuai Zhu, Shuai Zhu, Hanqing Wang, Hanqing Wang, Jinling He, Jinling He, Lingqi Yang, Lingqi Yang, Ning Zhou, Ning Zhou, Lingling Zu, Lingling Zu, Xiaohong Xu, Zuoqing Song, Zuoqing Song, Song Xu, Song Xu   +22 more
doaj   +1 more source

Thymic metastasis from lung carcinoma [PDF]

Interactive CardioVascular and Thoracic Surgery, 2011
Primary thymic carcinomas are well known but thymic metastases are very rare. To our knowledge a thymic metastasis from lung carcinoma has never been reported. We report the case of a metastatic lung cancer to the thymus, five years after a lobectomy for a stage I lung adenocarcinoma.
Pierre, Demondion, Pierre, Validire, Jean, Trédaniel, Dominique, Gossot   +3 more
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The Expression of RTN1 in Lung Adenocarcinoma and 
Its Effect on Immune Microenvironment

Chinese Journal of Lung Cancer, 2022
Background and objective Reticulosome family gene 1 (RTN1) is a reticulosome-encoding gene associated with the endoplasmic reticulum. RTN1 plays a key role in membrane trafficking or neuroendocrine secretion of neuroendocrine cells, while RTN1 serves as ...
Shuai ZHU, Lingling ZU, Song XU
doaj   +1 more source

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]

, 2014
Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C, Chaturvedi, Aashi, Grossmann, Allie H, Hoffman, Laura M, Jensen, Christopher C, Lessnick, Stephen L, Lin, Yi-Chun, Randall, R Lor, Welm, Alana L   +8 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Meta-analysis of the Association between RASSF1A Gene 
Promoter Methylation and Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2015
Background and objective The CpG island aberrant promoter methylation in the tumor suppressor gene region plays an important role in the process of tumorigenesis.
Huijun WEI, Nianzhen FANG, Lili GUO, Zhihao WU, Qinghua ZHOU   +4 more
doaj   +1 more source

ORGAN SPECIFIC VASCULAR RESPONSE TO FIBROSIS AFFECTS BREAST CANCER METASTATIC ORGANOTROPISM [PDF]

, 2016
The solid tumor microenvironment, pre-metastatic niche, and fibrotic environment are known to have significant biochemical and biomechanical similarities to the fibrotic environment. All have significantly increased levels of factors such as TGFβ, HIF1α,
Fletcher, Eliot S, Fletcher, Eliot S
core   +1 more source