Results 251 to 260 of about 613,665 (308)

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

Prediction of bone or lung metastasis in prostate cancer using machine learning: a SEER-based study with external validation. [PDF]

Discov Oncol
Zhong M, Chen R.
europepmc   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source

The Ly6g^high Neutrophil Subset Dictates Breast Cancer Lung Metastasis via CD8⁺ T Cell Death. [PDF]

Cancer Commun (Lond)
Wang R, Liu X, Hou Y, Chen S, Liu Y, Lu Z, Chang C, Meng D, Chen J, Cui X, Shi Z, Wan X, Liu M.   +12 more
europepmc   +1 more source

Metabolic Crosstalk in Triple-Negative Breast Cancer Lung Metastasis: Differential Effects of Vitamin D and E in a Co-Culture System. [PDF]

Cancers (Basel)
Kanwal B, Pounraj S, Hanif R, Kovacevic Z.   +3 more
europepmc   +1 more source

Tumor neoantigen gene C7orf50 remodels the immune microenvironment by recruiting tumor-associated macrophages to promote hepatocellular carcinoma progression and lung metastasis. [PDF]

J Immunother Cancer
Li J, Ye X, Su S, Hu Z, Chen C, Gong Y, Li Z, Qi F, Li H, Mao L, Huang X.   +10 more
europepmc   +1 more source

Residual tumor cells after insufficient radiofrequency ablation promote lung metastasis by educating CD177^hiPAD4^hi neutrophils. [PDF]

Nat Commun
Huang N, Fang Y, Zheng S, Wu J, Huang G, Deng X, Guan Y, Liang B, Zeng D, Xu B, Huang Y, Rong X, Wang C, Bin J, Liao Y, Wu Z, Shi M, Liao W.   +17 more
europepmc   +1 more source

Exosome membrane-biomimetic nanomedicine targets the pre-metastatic niche <i>via</i> NF-κB inhibition to suppress breast cancer lung metastasis. [PDF]

Mater Today Bio
Tang R, Mao C, Hu C, Liu W, Bai J, Wang Y, Yang L, Qi H.   +7 more
europepmc   +1 more source

Protocol for isolation and flow cytometric analysis of interstitial macrophages in murine lung metastasis models. [PDF]

STAR Protoc
Jeong MR, Seok SH.
europepmc   +1 more source

Radiotherapy drives lung metastasis in PDAC via a RhoGTPase signaling shift towards MRCK-dependency

McLay K, Tesson M, Dutton L, Sun Y, Misquitta J, Stevenson K, Corbyn R, Lilla S, McGarry L, Maka N, Shaw R, Miller C, Carlin L, Chalmers A, Olson M, Morton J, Birch J.   +16 more
europepmc   +1 more source