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Lupus nephritis [PDF]

open access: yesNature Reviews Disease Primers, 2020
Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most patients with SLE who develop LN do so within 5 years of an SLE diagnosis and, in many cases, LN is the presenting manifestation resulting in the diagnosis of SLE ...
Hans-Joachim Anders   +2 more
exaly   +5 more sources

A study on the relationship between morphological lesions of lupus nephritis with demographic and biochemical findings [PDF]

open access: yesJournal of Preventive Epidemiology, 2022
Introduction: Lupus nephritis is one of the important aspects of systemic lupus erythematosus (SLE). Objectives: This study aimed to investigate possible relationship between pathological lesions of lupus nephritis classes and demographic and biochemical
Nasrin Tavassoli   +2 more
doaj   +1 more source

Increase in direct costs for health systems due to lupus nephritis: the case of Colombia

open access: yesEinstein (São Paulo), 2022
Objective Lupus nephritis is one of the most severe complications of systemic lupus erythematosus and it has been estimated that can occur in up to 60% of patients. Direct costs of lupus nephritis have not been studied in developing countries.
Sergio I Prada   +3 more
doaj   +1 more source

Novel Therapeutics for Management of Lupus Nephritis: What Is Next?

open access: yesKidney Medicine, 2023
Lupus nephritis is a severe, organ-threatening manifestation of systemic lupus erythematosus. The current standard of care in the treatment of lupus nephritis is limited to broad-spectrum immunosuppressants, which have significant concerns of short- and ...
Sayali B. Thakare   +5 more
doaj   +1 more source

Interleukin-17 expression positively correlates with disease severity of lupus nephritis by increasing anti-double-stranded DNA antibody production in a lupus model induced by activated lymphocyte derived DNA. [PDF]

open access: yesPLoS ONE, 2013
Lupus nephritis is one of the most serious manifestations and one of the strongest predictors of a poor outcome in systemic lupus erythematosus (SLE).
Zhenke Wen   +5 more
doaj   +1 more source

Dissecting signalling pathways associated with intrarenal synthesis of complement components in lupus nephritis

open access: yesRMD Open, 2022
Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus, attributed to increased morbidity and mortality. The in situ deposition of intrarenal immune complexes promote the accumulation of inflammatory cells and
Samy Hakroush   +2 more
doaj   +1 more source

Lupus Nephritis [PDF]

open access: yesSeminars in Nephrology, 2006
Lupus nephritis is one of the more serious manifestations of the systemic autoimmune disease, systemic lupus erythematosus, and is associated with considerable morbidity and even mortality. Treatment remains problematic, particularly in terms of controlling the underlying disease process while at the same time preventing unacceptable side effects of ...
Neerja, Agrawal   +2 more
openaire   +4 more sources

Comparison of clinical features and outcomes between patients with early and delayed lupus nephritis

open access: yesBMC Nephrology, 2020
Background Lupus nephritis is associated with increased risk of end-stage renal disease (ESRD) and all-cause mortality. We evaluated the clinical features and outcomes of patients with early and delayed lupus nephritis. Methods The medical records of 171
Sung Soo Ahn   +5 more
doaj   +1 more source

Molecular signatures of intrarenal complement receptors C3AR1 and C5AR1 correlate with renal outcome in human lupus nephritis

open access: yesLupus Science and Medicine, 2022
Objective Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE). Lupus nephritis is a major cause of kidney failure in patients with SLE, attributed to increased morbidity and mortality.
Samy Hakroush   +2 more
doaj   +1 more source

The Role of Anti-mCRP Autoantibodies in Lupus Nephritis

open access: yesKidney Diseases, 2023
Background: Lupus nephritis is characterized by multiple autoantibodies production. However, there are few autoantibodies associated with disease activity and prognosis.
Mo Yuan, Ying Tan, Ming-hui Zhao
doaj   +1 more source

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