Results 31 to 40 of about 161 (74)

<i>In vitro</i>-<i>in vivo</i> discord: A preclinical study of AZD2716 and its racemate with comparison to varespladib for the development of snake venom sPLA2 inhibitors. [PDF]

Toxicon X
Hearth JL, Surovtseva Y, Karjala Z, Casewell NR, Giang K, Lewin MR.   +5 more
europepmc   +1 more source

In Vitro Efficacy of Antivenom and Varespladib in Neutralising Chinese Russell's Viper (Daboia siamensis) Venom Toxicity. [PDF]

Toxins (Basel), 2023
Lay M, Liang Q, Isbister GK, Hodgson WC.
europepmc   +1 more source

In Vitro Neutralization of the Myotoxicity of Australian Mulga Snake (Pseudechis australis) and Sri Lankan Russell's Viper (Daboia russelii) Venoms by Australian and Indian Polyvalent Antivenoms. [PDF]

Toxins (Basel), 2022
Thakshila P, Hodgson WC, Isbister GK, Silva A.   +3 more
europepmc   +1 more source

Quercitrin neutralizes sPLA2IIa activity, reduces the inflammatory IL-6 level in PC3 cell lines, and exhibits anti-tumor activity in the EAC-bearing mice model. [PDF]

Front Pharmacol, 2022
Sophiya P, Urs D, K Lone J, Giresha AS, Krishna Ram H, Manjunatha JG, El-Serehy HA, Narayanappa M, Shankar J, Bhardwaj R, Ahmad Guru S, Dharmappa KK.   +11 more
europepmc   +1 more source

Human iPSC-based disease modeling studies identify a common mechanistic defect and potential therapies for AMD and related macular dystrophies. [PDF]

Dev Cell
Dalvi S, Roll M, Chatterjee A, Kumar LK, Bhogavalli A, Foley N, Arduino C, Spencer W, Reuben-Thomas C, Ortolan D, Pébay A, Bharti K, Anand-Apte B, Singh R.   +13 more
europepmc   +1 more source

Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom. [PDF]

Toxins (Basel), 2018
Lewin MR, Gutiérrez JM, Samuel SP, Herrera M, Bryan-Quirós W, Lomonte B, Bickler PE, Bulfone TC, Williams DJ.   +8 more
europepmc   +1 more source

Sinapicacid Inhibits Group IIA Secretory Phospholipase A₂ and Its Inflammatory Response in Mice. [PDF]

Antioxidants (Basel), 2022
Giresha AS, Urs D, Pundalik S, Meti RS, Pramod SN, Supreetha BH, Somegowda M, Dharmappa KK, El-Shehawi AM, Albogami S, Elseehy MM, Alaklabi A, Elansary HO, Mehder AOA, Mahmoud EA.   +14 more
europepmc   +1 more source

Lysophosphatidylcholine induced by fat transplantation regulates hyperalgesia by affecting the dysfunction of ACC perineuronal nets. [PDF]

iScience
Li J, Li Z, Liu Y, Li Y, Wu Y, Manyande A, Li Z, Xiang H.   +7 more
europepmc   +1 more source

Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16.

Investigative Ophthalmology and Visual Science, 2005
Y. Hori, S. Spurr-Michaud, C. L. Russo, P. Argüeso, I. Gipson   +4 more
semanticscholar   +1 more source

Phospholipase A₂ Drives Tumorigenesis and Cancer Aggressiveness through Its Interaction with Annexin A1. [PDF]

Cells, 2021
Vecchi L, Araújo TG, Azevedo FVPV, Mota STS, Ávila VMR, Ribeiro MA, Goulart LR.   +6 more
europepmc   +1 more source