Results 21 to 30 of about 1,603 (190)
Synthesis of the Core Structure of Palhinine A
European Journal of Organic Chemistry, Volume 2021, Issue 17, Page 2549-2556, May 7, 2021., 2021 An approach to the core structure of the alkaloid palhinine A is presented. Starting with an easily available 2,5‐disubstituted cyclohexanone an allyl group was introduced into the 3‐position by a Grignard addition/oxy‐Cope sequence. A subsequent transannular aldol reaction led to a bicyclo[2.2.2]octanone derivative.
Dominik Gaugele, Martin E. Maier
wiley +1 more source
Total Synthesis of Lyconesidine B, a Lycopodium Alkaloid with an Oxygenated, Amine-Type Fawcettimine Core [PDF]
, 2021 This report describes the total synthesis of the complex, oxygenated tetracyclic alkaloid, lyconesidine B. The key synthetic challenge involves diastereoselective generation of a decahydroquinoline ring with a quaternary carbon at the angular position ...
Kurose, Tomohiro +3 more
core +1 more source
Chemical Composition of Cynanchum auriculatum Royle Ex Wight and Its Potential Role in Ameliorating Colitis. [PDF]
Food Sci NutrIn this study, the water extract of Cynanchum auriculatum Royle ex Wight root (CW) was prepared and its chemical composition was characterized using UPLC‐Q‐TOF‐MS. CW significantly alleviated DSS‐induced colitis in mice, as demonstrated by increased colon length, reduced disease activity index scores, and decreased histological damage in colon tissues.
Li S +10 more
europepmc +2 more sources
Oxidative Medicine and Cellular Longevity, Volume 2021, Issue 1, 2021., 2021 Osteoarthritis (OA), a highly prevalent chronic joint disease, involves a complex network of inflammatory mediators that not only triggers pain and cartilage degeneration but also accelerates disease progression. Traditional Chinese medicinal shenjinhuoxue mixture (SHM) shows anti‐inflammatory and analgesic effects against OA with remarkable clinical ...
Xiaoqin Ma +8 more
wiley +1 more source
Differentiation Effect of Two Alkaloid Fractions from Vietnamese Lycopodiaceae on Mouse Neural Stem Cells [PDF]
, 2022 Various Lycopodium alkaloids have been studied for their various biological activities including anti-inflammatory, antioxidant, immunomodulatory, and neuroprotective activities.
Hoang, My Hanh Thi +8 more
core +2 more sources
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
, 2016 The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D. +2 more
core +2 more sources
BMC Plant Biology, 2010 Background Plants of the Huperziaceae family, which comprise the two genera Huperzia and Phlegmariurus, produce various types of lycopodium alkaloids that are used to treat a number of human ailments, such as contusions, swellings and strains.
Steinmetz André +7 more
doaj +1 more source
N-demethyl-sauroxine, a novel Lycodine Group alkaloid from Huperzia saururus [PDF]
, 2013 The present study describes the isolation and identification of N-demethyl-sauroxine, a novel Lycopodium alkaloid obtained from Huperzia saururus (Lam.) Trevis. (Lycopodiaceae).
Agnese, Mariel +3 more
core +2 more sources
Antiprotozoal activity and cytotoxicity of Lycopodium clavatum and Lycopodium complanatum subsp. chamaecyparissus extracts [PDF]
, 2013 Objective: the aim of this study is to investigate the in vitro antioxidant activity, the total phenol and flavonoid content and the possible protective effects of commercial propolis on gentamicin-induced nephrotoxicity in rabbits.
Brun, Reto +5 more
core +1 more source
Quinolizidine alkaloid biosynthesis: recent advances and future prospects
Frontiers in Plant Science, 2012 Lys-derived alkaloids, including piperidine, quinolizidine, indolizidine, and lycopodium alkaloids, are widely distributed throughout the plant kingdom.
Somnuk eBunsupa +3 more
doaj +1 more source