Results 21 to 30 of about 1,605 (189)
Strategies and Efforts towards the Total Synthesis of Palhinine Alkaloids
The palhinine family of Lycopodium alkaloids were first reported in 2010, which feature an intriguing isotwistane carbon cage and a nine-membered azonane ring.
Yu-Yan Liang +3 more
doaj +1 more source
Highlighting the Rich Chemistry of the Allenone Moiety
Abstract Conjugated and non‐conjugated allenones appear as recurring motifs in organic synthesis, natural products and mechanistic investigations showing unique properties and applications. The ability of allenones to build cycles has provided a direct access to strained systems, medium‐sized rings, arenes, heterocycles and complex polycycles.
José M. Alonso, Pedro Almendros
wiley +1 more source
Skeletal Editing: Interconversion of Arenes and Heteroarenes
Abstract Skeletal editing involves making specific point‐changes to the core of a molecule through the selective insertion, deletion or exchange of atoms. It thus represents a potentially powerful strategy for the step‐economic modification of complex substrates and is a perfect complement to methods such as C−H functionalization that target the ...
Ben W. Joynson, Liam T. Ball
wiley +1 more source
In view of the abundant evidence that Lycopodiaceae alkaloids, including the well-known huperzine A (HupA), are among the potent acetylcholinesterase (AChE) inhibitors, an attempt was made to search for new compounds responsible for this property.
Aleksandra Dymek +5 more
doaj +1 more source
Early land plants: Plentiful but neglected nutritional resources for herbivores?
In this paper, we explore the unknown reason(s) why herbivores rarely seem to attack early land plants like mosses and ferns. Our study, in which we looked at the performance of an arthropod and a gastropod on 15 species of such plants, yields surprising results that disqualify some of the common notions about early land plants.
Audrey Duhin +3 more
wiley +1 more source
In Vitro Bioactivities of Plants Used against Skin Diseases in the Eastern Free State, South Africa
Skin diseases are a worldwide issue, accounting for approximately 34% of all occupational illnesses. The aim of this study was to investigate medicinal plants used to treat wounds and skin diseases in the eastern Free State Province of South Africa.
Valeria Makhosazana Xaba +3 more
doaj +1 more source
Alzheimer’s disease (AD) is a common neurodegenerative brain disorder that causes cellular response alterations, such as impaired cholinergic mechanism, amyloid‐beta (Aβ) AD aggregation, neuroinflammation, and several other pathways. AD is still the most prevalent form of dementia and affects many individuals across the globe.
Fahadul Islam +10 more
wiley +1 more source
Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014-2023). [PDF]
This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Sipoloni VM +5 more
europepmc +2 more sources
The incidence of obesity and over bodyweight is emerging as a major health concern. Obesity is a complex metabolic disease with multiple pathophysiological clinical conditions as comorbidities are associated with obesity such as diabetes, hypertension, cardiovascular disorders, sleep apnea, osteoarthritis, some cancers, and inflammation‐based clinical ...
Vikram Kumar +6 more
wiley +1 more source
Oxidation of cadaverine by putrescine oxidase from Rhodococcus erythropolis
Abstract BACKGROUND Putrescine oxidase (EC 1.4.3.10) is of interest for the microbial production of unsubstituted platform nitrogen (N‐)heterocycles, because it only requires inexpensive oxygen as co‐substrate. Putrescine oxidase from Rhodococcus erythropolis (Re‐PuO) was shown previously to catalyze the oxidation of cadaverine; however, there is ...
Valentine E Anyanwu +3 more
wiley +1 more source

