Results 31 to 40 of about 3,343 (218)

Lycorine weakens tamoxifen resistance of breast cancer via abrogating HAGLR‐mediated epigenetic suppression on VGLL4 by DNMT1

open access: yesKaohsiung Journal of Medical Sciences, 2023
Much is known about the significance of lycorine, a natural alkaloid, in combating various types of cancer, including breast cancer (BC), but whether it participates in regulating tamoxifen (TAM) resistance and its underlying mechanism remain to be ...
Jing Zhai, Jun‐Feng Jiang, Lei Shi
doaj   +1 more source

Lycorine inhibits angiogenesis by docking to PDGFRα

open access: yesBMC Cancer, 2022
AbstractLycorine (Lyc) is a natural alkaloid derived from medicinal plants of the Amaryllidaceae family. Lyc has been reported to inhibit the recurrence and metastasis of different kinds of tumors. However, Lyc’s effect on angiogenesis and its specific mechanism are still not clear. This study was designed to test the antiangiogenesis effect of Lyc and
Fei Lv, XiaoQi Li, Ying Wang
openaire   +3 more sources

Identification of Alkaloids from Hippeastrum aulicum (Ker Gawl.) Herb.(Amaryllidaceae) Using CGC-MS and Ambient Ionization Mass Spectrometry (PS-MS and LS-MS) [PDF]

open access: yes, 2017
Amaryllidaceae alkaloids are well-known isoquinolines which have demonstrated a wide range of biological activities such as antiviral, anticancer, acetylcholinesterase inhibition, antimalarial, among others.
Andrade, Jean Paulo de   +7 more
core   +1 more source

Apoptosis Induction of Lycorine on Lung Cancer NCI-H460 Cells and Related Mechanism

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To investigate the effect of lycorine on the proliferation inhibition and apoptosis induction in human lung cancer NCI-H460 cells, and to explore the anti-tumor mechanism of lycorine.
LI Juwei, YANG Yang
doaj   +1 more source

Alkaloid Compound Identification of Rhodomyrtus Tomentosa Stem as Biology Instructional Material for Senior High School X Grade [PDF]

open access: yes, 2016
Rhodomyrtus tomentosais one of herbs which belongs to myrtaceaefamily. This plant possessesalkaloid which is efficacious as anti diarrhea, anti diabetes, anti microbial, and anti malaria, however some alkaloid compoundsare poisonous. Thus,it is necessity
Ningrum, R. (Retno)   +2 more
core   +4 more sources

Lycorine reduces mortality of human enterovirus 71-infected mice by inhibiting virus replication

open access: yesVirology Journal, 2011
Human enterovirus 71 (EV71) infection causes hand, foot and mouth disease in children under 6 years old and this infection occasionally induces severe neurological complications. No vaccines or drugs are clinical available to control EV71 epidemics.
Qin Chuan   +5 more
doaj   +1 more source

Biological Activities of Snowdrop (Galanthus spp., Family Amaryllidaceae)

open access: yesFrontiers in Pharmacology, 2021
Snowdrop is an iconic early spring flowering plant of the genus Galanthus (Amaryllidaceae). Galanthus species (Galanthus spp.) are economically important plants as ornaments. Galanthus spp has gained significance scientific and commercial interest due to
Chee Kei Kong   +13 more
doaj   +1 more source

Toxic plants and companion animals. [PDF]

open access: yes, 2009
Poisoning by substances of plant origin is unusual in both dogs and cats, yet it is possible; as many veterinarians do not know which plants can contain toxic active principles, the possibility of intoxication by ornamental plants commonly used to ...
SEVERINO, LORELLA
core   +1 more source

Cytotoxicity and Antiviral Properties of Alkaloids Isolated from Pancratium maritimum [PDF]

open access: yes, 2022
Ten Amaryllidaceae alkaloids (AAs) were isolated for the first time from Pancratium maritimum collected in Calabria region, Italy. They belong to different subgroups of this family and were identified as lycorine, which is the main alkaloid, 9-O ...
Berthoux L.   +7 more
core   +1 more source

Lycorine inhibits MDA-MB-231 breast cancer cell proliferation, migration and invasion that are associated with Wnt/β-catenin signaling

open access: yesBangladesh Journal of Pharmacology, 2018
This study was aimed to determine the effects of lycorine, a toxic crystalline alkaloid, on MDA-MB-231 breast cancer cells proliferation, migration and invasion, and to investigate the mechanism involved.
Xia-Liang Chen
doaj   +1 more source

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