Results 111 to 120 of about 43,762 (300)
Nature Communications, 2020 Proteolytical processing of the growth factor VEGFC through the concerted activity of CCBE1 and ADAMTS3 is required for lymphatic development to occur.
Guangxia Wang +10 more
semanticscholar +1 more source
Lymphangiogenesis and cancer metastasis
Frontiers in Bioscience, 2011 Lymphangiogenesis remains a fascinating biological process that plays a crucial role in both normal tissue development and several lymphatic diseases. The last few years have witnessed a rapid progression in understanding the development and regulation of the lymphatic system which provided insight on several pathological processes including cancer ...
Mahir A A, Al-Rawi, Wen G, Jiang
openaire +2 more sources
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva +7 more
wiley +1 more source
Adenosine A2a receptor promotes lymphangiogenesis and lymph node metastasis
OncoImmunology, 2019 The formation of new lymphatic vessels, or lymphangiogenesis, is a critical step of the tissue repair program. In pathological conditions involving chronic inflammation or tumorigenesis, this process is often dysregulated and can contribute to disease ...
Bertrand Allard +6 more
doaj +1 more source
High Mobility Group Box-1 Promotes Inflammation-Induced Lymphangiogenesis via Toll-Like Receptor 4-Dependent Signalling Pathway. [PDF]
PLoS ONE, 2016 Lymphangiogenesis in inflammation has received considerable attention in recent years. Administration of modulating lymphangiogenesis provides more possibilities of treating inflammation-associated diseases.
Longhui Han +6 more
doaj +1 more source
The Role of VEGF family in angiogenesis, tumor growth and metastasis [PDF]
, 2014 Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most ...
Yang, Xiaojuan
core +1 more source
Mast Cells, Angiogenesis and Lymphangiogenesis in Human Gastric Cancer
International Journal of Molecular Sciences, 2019 Gastric cancer is diagnosed in nearly one million new patients each year and it remains the second leading cause of cancer-related deaths worldwide. Although gastric cancer represents a heterogeneous group of diseases, chronic inflammation has been shown
G. Sammarco +11 more
semanticscholar +1 more source
iLABMED, EarlyView.We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang +6 more
wiley +1 more source
Lymphangiogenèse et progression tumorale [PDF]
, 2007 National audienceNumerous data show a functional link between lymphangiogenesis, lymph node invasion by tumoral cells and metastasis. During the last decade, the identification of lymphatic endothelial cell-specific markers has allowed the investigation ...
Feige, Jean-Jacques, Vittet, Daniel
core +1 more source
Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling [PDF]
, 2017 Lymphangiogenesis occurs in inflammation and wound healing, yet its functional roles in these processes are not fully understood. Consequently, clinically relevant strategies for therapeutic lymphangiogenesis remain underdeveloped, particularly using ...
Achen +78 more
core +1 more source