Results 131 to 140 of about 43,762 (300)

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Future Needs in Mast Cell Biology. [PDF]

, 2019
The pathophysiological roles of mast cells are still not fully understood, over 140 years since their description by Paul Ehrlich in 1878. Initial studies have attempted to identify distinct "subpopulations" of mast cells based on a relatively small ...
de Paulis, Amato, Galli, Stephen J, Marone, Gianni, Varricchi, Gilda   +3 more
core   +2 more sources

Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications

Advanced Materials, Volume 38, Issue 2, 8 January 2026.
Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi, Chunyao Wang, Xuan Mei, Ben Zhang, Junxi Wu, Rylie A. Green, Yu Shrike Zhang, Wenmiao Shu   +7 more
wiley   +1 more source

Apelin promotes lymphangiogenesis and lymph node metastasis [PDF]

, 2015
Whereas the role of the G-protein-coupled APJ receptor and its ligand, apelin, in angiogenesis has been well documented, the ability of the apelin/APJ system to induce lymphangiogenesis and lymphatic metastasis has been largely unexplored.
Berger W, Berta, Judit, Döme, Balázs, Garay, Tamás, Groger M, Grusch M, Hegedűs, Balázs, Hoda MA, Klepetko W, Laszlo, Viktoria, Masri B, Paku, Sándor, Rozsas A, Rényi-Vámos, Ferenc István, Torok S, Tóvári, József   +15 more
core  

High-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection [PDF]

, 2016
Acknowledgments The authors thank M. Robertson and R. Fordyce for technical support during the duration of the study. The work performed in Aberdeen was supported by grant from Action Medical Research UK (SP4328; London, England, UK), NHS Grampian ...
Amescua, Guillermo, Forrester, John V., Hendricks, Robert L., Knickelbein, Jared E., Kuffova, Lucia, Medina, Carlos, Rowe, Alexander M., Yu, Tian   +7 more
core   +1 more source

Conjugated Bile Acids Promote Lymphangiogenesis by Modulation of the Reactive Oxygen Species–p90RSK–Vascular Endothelial Growth Factor Receptor 3 Pathway [PDF]

, 2023
Priyanka Banerjee, Subhashree Kumaravel, Sukanya Roy, Niyanshi Gaddam, Johnny Odeh, Kayla J. Bayless, Shannon Glaser, Sanjukta Chakraborty   +7 more
openalex   +1 more source

S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1β

Journal of Experimental Medicine, 2017
Metastasis is the primary cause of cancer death. The inflammatory tumor microenvironment contributes to metastasis, for instance, by recruiting blood and lymph vessels.
Benjamin Weichand, R. Popp, Sarah Dziumbla, Javier Mora, E. Strack, Eiman Elwakeel, Ann-Christin Frank, K. Scholich, Sandra C. Pierre, S. Syed, Catherine Olesch, Julia Ringleb, Bilge Ören, C. Döring, R. Savai, M. Jung, A. von Knethen, B. Levkau, I. Fleming, A. Weigert, B. Brüne   +20 more
semanticscholar   +1 more source

Astrocyte–vascular interplay in Alzheimer's disease pathology: Novel insights into stage‐specific biomarkers and therapeutic targets

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION We examined how neurovascular and astrocytic response alter cognition in Alzheimer's disease (AD). METHODS Cognitive scores, biomarkers of AD and astrocytic activation, vascular factors, and brain structure data from 693 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants were analyzed using analysis of covariance ...
Zehu Sheng, Yuhao Chen, Ming Chen, Shuyu Liang, Jingyi Wang, Yingxi Chen, Rengui Li, Boyuan Xia, Kangjinyuan Gou, Siyuan Liu, Alzheimer's Disease Neuroimaging Initiative, Weihua Yu, Yang Lü   +12 more
wiley   +1 more source

Reprogramming lymphatic endothelial glucose metabolism for the treatment of lymphangiogenesis-related disease

Pharmacological Research
Lymphangiogenesis plays important roles in the pathogenesis of several human diseases, including keratitis, transplant rejection, and cancers. Dysregulated glucose metabolism has emerged as a critical driver of pathological lymphangiogenesis.
Ziran Zhang, Fan Ye, Huiying Zhang, Xiumiao Li, Wan Mu, Keran Li, Biao Yan   +6 more
doaj   +1 more source

Role of Lymphatic Vessels in Tumor Immunity: Passive Conduits or Active Participants? [PDF]

, 2018
Research in lymphatic biology and cancer immunology may soon intersect as emerging evidence implicates the lymphatics in the progression of chronic inflammation and autoimmunity as well as in tumor metastasis and immune escape. Like the blood vasculature,
Lund, Amanda, Swartz, Melody
core