Results 71 to 80 of about 23,756 (251)
Computational and Mathematical Methods in Medicine, 2003 While much effort is given to the modelling of tumour angiogenesis, little attention is paid to lymphangiogenesis and its potential role in tumour progression and metastasis. This is due at least in part to the controversy that surrounds tumour lymphangiogenesis—opinion is divided as to whether tumours actively promote the development of lymph channels
Catherine R. Tait, Pamela F. Jones
openaire +1 more source
CRIP1 Reshapes the Gastric Cancer Microenvironment to Facilitate Development of Lymphatic Metastasis
Advanced Science, 2023 Lymphangiogenesis in tumors provides an auxiliary route for cancer cell invasion to drainage lymph nodes, facilitating the development of lymphatic metastasis (LM).
Zhonghua Wu +9 more
doaj +1 more source
Biomedicines, 2021 Chondrosarcoma is a malignant bone tumor with high metastatic potential. Lymphangiogenesis is a critical biological step in cancer metastasis. WNT1-inducible signaling pathway protein 3 (WISP-3) regulates angiogenesis and facilitates chondrosarcoma ...
Chih-Yang Lin +9 more
doaj +1 more source
Oncogene, 2018 Cancer-secreted exosomal miRNAs are emerging mediators of cancer-stromal cross-talk in the tumor environment. Our previous miRNAs array of cervical squamous cell carcinoma (CSCC) clinical specimens identified upregulation of miR-221-3p.
Chenfei Zhou +11 more
semanticscholar +1 more source
Cancer Science, EarlyView.Tumor‐associated neutrophils (TANs) enhance STAT3 phosphorylation by upregulating aquaporin 9 (AQP9) to promote breast cancer (BC) progression. AQP9 may be crucial for TAN‐mediated BC progression and is a novel target for immunotherapy in patients with BC.
Wuqin Xu +5 more
wiley +1 more source
Lymphangiogenesis and cancer metastasis
Frontiers in Bioscience, 2011 Lymphangiogenesis remains a fascinating biological process that plays a crucial role in both normal tissue development and several lymphatic diseases. The last few years have witnessed a rapid progression in understanding the development and regulation of the lymphatic system which provided insight on several pathological processes including cancer ...
A. A. Mahir Al-Rawi, Wen Guo Jiang
openaire +2 more sources
Scientific Reports, 2017 Lymphangiogenesis is essential for fluid homeostasis in vascularized tissues. In the normally avascular cornea, however, pathological lymphangiogenesis mediates diseases like corneal transplant rejection, dry eye disease, and allergy.
Deniz Hos +10 more
doaj +1 more source
Mast Cells, Angiogenesis and Lymphangiogenesis in Human Gastric Cancer
International Journal of Molecular Sciences, 2019 Gastric cancer is diagnosed in nearly one million new patients each year and it remains the second leading cause of cancer-related deaths worldwide. Although gastric cancer represents a heterogeneous group of diseases, chronic inflammation has been shown
G. Sammarco +11 more
semanticscholar +1 more source
Nature Communications, 2020 Proteolytical processing of the growth factor VEGFC through the concerted activity of CCBE1 and ADAMTS3 is required for lymphatic development to occur.
Guangxia Wang +10 more
semanticscholar +1 more source
Lymphangiogenesis in the heart
The FASEB Journal, 2009 Our goal was to follow the development of the lymphatic system in the developing heart using markers that identify the lymphatics in adult tissues. The transcription factor Prox‐1 identified a branching network of vessels in the avian embryonic heart that first appeared on the outflow tract at Embryonic Day 5 (Hamburger and Hamilton Stage 25‐26).
Yong Qiu Doughman +8 more
openaire +2 more sources