Diagnosis and surgical management of septic peritonitis in small animals: A review
Veterinary Surgery, EarlyView.Abstract Background Septic peritonitis (SP) is a complex disease with significant morbidity and mortality. Diagnosis can be challenging, and lack of a timely diagnosis may impact survival. Aim The aim of this review was to synthesize current knowledge on the diagnosis and surgical management of SP in dogs and cats.
Bonnie G. Campbell, Shana K. O'Marra
wiley +1 more source
Targeting glycolytic reprogramming by tsRNA-0032 for treating pathological lymphangiogenesis
Cell Death and DiseaseLymphangiogenesis is vital for tissue fluid homeostasis, immune function, and lipid absorption. Abnormal lymphangiogenesis has been implicated in several diseases such as cancers, inflammatory, and autoimmune diseases.
Fan Ye +7 more
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Atypical E2fs control lymphangiogenesis through transcriptional regulation of Ccbe1 and Flt4. [PDF]
PLoS ONE, 2013 Lymphatic vessels are derived from venous endothelial cells and their formation is governed by the Vascular endothelial growth factor C (VegfC)/Vegf receptor 3 (Vegfr3; Flt4) signaling pathway.
Bart G M W Weijts +3 more
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Transcriptomic Profiles of Monocyte-Derived Macrophages in Response to Escherichia coli is Associated with the Host Genetics. [PDF]
, 2020 Reactive Nitrogen Species (RNS) are a group of bactericidal molecules produced by macrophages in response to pathogens in a process called oxidative burst.
Cánovas, Angela +5 more
core
The Role of VEGF family in angiogenesis, tumor growth and metastasis [PDF]
, 2014 Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most ...
Yang, Xiaojuan
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Radiogenic Lymphangiogenesis in the Skin [PDF]
The American Journal of Pathology, 2007 The time course of microvascular changes in the environment of irradiated tumors was studied in a standardized human protocol. Eighty skin biopsies from 40 patients with previously treated primary breast cancer were taken from irradiated skin and corresponding contralateral unirradiated control areas 2 to 8 weeks, 11 to 14 months, or 17+ months after ...
Susanne, Jackowski +8 more
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High Phosphate Load Induces De Novo Formation of Tertiary Lymphoid Structures in the Kidney
The FASEB Journal, Volume 39, Issue 24, 31 December 2025.Graphical illustration of renal alterations under varying phosphate load: High phosphate load induces fibrosis, tubular injury, impaired renal function, and de novo formation of perivascular tertiary lymphoid structures. Under normal phosphate load, fibrosis, functional decline, and tubular injury are absent, while T‐ and B‐ cell aggregates are present
Nina Weingärtner +8 more
wiley +1 more source
Signal Transduction and Targeted TherapyEphrinB2 (erythropoietin-producing hepatoma interactor B2) is a key Eph/ephrin family member, promoting angiogenesis, vasculogenesis, and lymphangiogenesis during embryonic development. However, the role of EphrinB2 in cardiac lymphangiogenesis following
Yingnan Bai +19 more
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Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway [PDF]
, 2016 BACKGROUND AND PURPOSE Lymphangiogenesis is an important biological process associated with the pathogenesis of several diseases, including metastatic dissemination, graft rejection, lymphoedema and other inflammatory disorders.
Blacher, S. +5 more
core
Supplementary Figure Legends 1-5 from Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer [PDF]
, 2023 Young A. Yoo +7 more
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