Results 1 to 10 of about 105,340 (191)
Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development [PDF]
The lymphatic system controls fluid homeostasis and the clearance of macromolecules from interstitial compartments. In mammals brain lymphatics were only recently discovered, with significant implications for physiology and disease. We examined zebrafish
Max van Lessen+5 more
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Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment (176.25) [PDF]
Peripheral self-tolerance eliminates lymphocytes specific for tissue-specific antigens not encountered in the thymus. Recently, we demonstrated that lymphatic endothelial cells in mice directly express peripheral tissue antigens, including tyrosinase ...
Jarish Cohen+2 more
openalex +3 more sources
TGF-β signaling in lymphatic vascular vessel formation and maintenance
Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
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Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
doaj +1 more source
At present, only a few reports have addressed the possible contribution of the lymphatic vascular system to the pathogenesis of systemic sclerosis (SSc).
Irene Rosa+6 more
doaj +1 more source
Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker+16 more
core +10 more sources
In our previous study, we found that lymphatic vessels stimulate hair follicle growth through paracrine effects on dermal papilla cells. However, the paracrine factors secreted from cutaneous lymphatic vessels that can activate dermal papilla cells are ...
Sun-Young Yoon, Michael Detmar
doaj +1 more source
Aberrant lymphatic endothelial progenitors in lymphatic malformation development.
Lymphatic malformations (LMs) are vascular anomalies thought to arise from dysregulated lymphangiogenesis. These lesions impose a significant burden of disease on affected individuals.
June K Wu+10 more
doaj +1 more source
The intestinal lymphatic system: Functions and metabolic implications [PDF]
The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Cifarelli, Vincenza, Eichmann, Anne
core +2 more sources
Oral treatment with the dual-receptor tyrosine kinase inhibitor AEE788 effectively reduces the number of peritumoral lymphatic vessels and the incidence of lymph node metastasis in nude mice with human HT29 colon cancer cells growing in the cecum ...
Robert B. Rebhun+5 more
doaj +1 more source